| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 4:00 pm - 6:00 pm | Reception at Posters |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | FRONTIERS IN PROTEOGLYCAN RESEARCH |
| Discussion Leader: James Kimura (University of Hawaii, Honolulu, USA) |
| 7:30 pm | Timothy Hardingham (University of Manchester, UK)
"Proteoglycans, Some Assumptions and Predictions" |
| 8:15 pm | Alana Majors (Cleveland Clinic Foundation, USA)
"Alterations of the Extracellular Matrix by Endoplasmic Reticulum Stress" |
| 8:40 pm | Kazuyuki Sugahara (Kobe University, Japan)
"Chondroitin Sulfate on Syndecan-1 and Syndecan-4:
A Novel Function to Control binding of Midkine, Pleiotrophin and bFGF" |
| 9:00 pm | John Gallagher (Paterson Institute, Manchester, UK)
"Heparan Sulphate: Imprints in the Chain" |
| 9:15 pm | Sarah Knox (University of Minnesota, USA)
"Genetics meets Biochemistry: Interactions of Dally in vivo and in vitro" |
| 9:30 pm | Reception and Discussion at Posters |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Photo |
| 9:00 am - 12:30 pm | GLYCOSAMINOGLYCAN BIOSYNTHESIS |
| Discussion Leader: Masaki Yanagishita (Tokyo Medical and Dental University, Japan) |
| 9:00 am | Osami Habuchi (Aichi University of Education, Japan)
"Sulfation Mechanisms of Chondroitin Sulfate" |
| 9:40 am | Marion Kusche-Gullberg (University of Uppsala, Sweden)
"Heparan Sulfate: Chain Elongation, O-Sulfation and O-Desulfation" |
| 10:30 am | Coffee Break |
| 11:00 am | Markku Tammi (University of Kuopio, Finland)
"Regulation of Hyaluronan Synthase Expression in Epidermal Keratinocytes" |
| 11:40 am | Robert Wilkins (University of Oxford, UK)
"Membrane Transporters - Influence on Glycosaminoglycan Synthesis" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | PROTEOGLYCAN DEGRADOMICS |
| Discussion Leader: Amanda Fosang (University of Melbourne, Australia) |
| 7:30 pm | John Sandy (Shriners Hospital for Children, USA)
"The Catabolic Complex for Aggrecan Degradation" |
| 8:05 pm | Jeremy Turnbull (University of Liverpool, UK)
"Heparan Sulfate Orchestration of APP Proteolysis by BACE: Role in Alzheimers Disease"
|
| 8:30 pm | Viji Shridhar (Mayo Clinic Cancer Center, Rochester, USA)
"Role of HSulf-1 in Heparin Binding Growth Factor Signalling" |
| 8:55 pm | Paul Weigel (University of Oklahoma, USA)
"Glycosaminoglycan Recognition, Endocytosis, and Degradation Mediated by Mammalian HARE" |
| 9:30 pm | Discussion at Posters |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | PROTEOGLYCANS IN REGULATION OF CELL DYNAMICS |
| Discussion Leader: Malcolm Davies (University of Wales, UK) |
| 9:00 am | Tom Wight (Hope Heart Insitute, USA)
"Versican or Versicant: Master Regulators of Cell Phenotype" |
| Liliana Schaefer (University of Munster, Germany)
"Decorin and Biglycan as Regulators of Renal Fibrosis" |
| 10:00 am | Coffee Break |
| 10:30 am | Deanna Beauvais (University of Wisconsin, USA)
"The Ectodomain of Syndecan-1 is Required for αVß3 Integrin Dependent Signalling in Human Mammary Carcinoma Cells" |
| 11:15 am | Lisbet Camper (University of Lund, Sweden)
"Domains of cartilage matrix proteins modulate cellular activities by interacting with cell surface heparan sulfate" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | PROTEOGLYCANS IN CANCER |
| Discussion Leader: Alan Rapraeger (University of Wisconsin, USA) |
| 7:30 pm | Carolyn Alexander (University of Wisconsin, USA)
"Syndecan-1 in Mammary Gland Tumor Formation" |
| 8:10 pm | Anna Masellis (Virginia Piper Cancer Institute, USA)
"The Bone Marrow ECM in the Development of Multiple Myeloma" |
| 8:40 pm | Israel Vlodavsky (Technion, Israel)
"Heparanase in Tumor Angiogenesis and Metastasis" |
| 9:30 pm | Discussion at Posters |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | PROTEOGLYCANS IN INFLAMMATION |
| Discussion Leader: Carol De La Motte (Cleveland Clinic Foundation, USA) |
| 9:00 am | Rashmin Savani (Children's Hospital of Philadelphia, USA)
"Glycoconjugates in Lung Inflammation - from Bench to Bedside" |
| 9:25 am | Rosanna Forteza (University of Miami, USA)
"Glycosaminoglycan/Protease Complexes in the Pathogenesis of Asthma" |
| 10:00 am | Coffee Break |
| 10:30 am | Aled Phillips (University of Wales, Cardiff, UK)
"Hyaluronan Modifies TGF-beta 1 Production and Signalling in Kidney Tubular Epithelial Cells" |
| Anthony Day (University of Oxford, UK)
"Formation of Cross-linked Hyaluronan Matrices during Inflammation" |
| 11:45 am | Katalin Mikecz (Rush Medical College, USA)
"Regulation of Inflammatory Cell Migration to the Joints in Proteoglycan (Aggrecan)-induced Murine Arthritis" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | PROTEOGLYCANS IN DEVELOPMENT AND REGENERATIVE MEDICINE |
| Discussion Leader: Cheryl Knudson (Rush Medical College, USA) |
| 7:30 pm | Pankaj Gupta (VA Hospital, U Minnesota, USA)
"The Matrix Environment and Plasticity of Stem Cells" |
| 8:00 pm | Ronald Midura (The Cleveland Clinic Foundation, USA)
"Hyaluronan, Progenitor Cell Growth and Differentiation in Bone Formation" |
| 8:25 pm | Dena Howland (University of Florida, USA)
"Chondroitin Sulfate Proteoglycans in Spinal Cord Repair" |
| 8:50 pm | Yu Yamaguchi (The Burnham Institute, USA)
"The Brain without Heparan Sulfate: Novel Insights from the EXT1 Knockout" |
| 9:30 pm | Discussion at Posters |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | STRUCTURAL GLYCAN BIOLOGY AND THERAPEUTICS |
| Discussion Leader: Barbara Mulloy (NIBSC, UK) |
| 9:00 am | Mirek Cygler (Biotechnology Research NRC, Canada)
"Structural View of Enzymatic Mechanisms of Glycosaminoglycan Lyases" |
| John Sheehan (University of North Carolina, USA)
"Epithelial Structural Glycoconjugates in the Airway" |
| 10:00 am | Coffee Break |
| 10:30 am | Akira Asari (Seikagaku Corporation, Japan)
"Novel Functions of Hyaluronan Oligosaccharides" |
| 11:45 am | Leif Dahlberg (University Hospital of Malmo, Sweden)
"Delayed Gadolinium Enhanced MRI of Cartilage Proteoglycans in Pre-Radiographic Early Stage Osteoarthritis" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | PROTEOGLYCANS - FROM BIOCHEMISTRY TO METABOLOMICS |
| Discussion Leader: Kathryn Vogel (University of New Mexico, USA) |
| 7:30 pm | Poster Awards |
| 8:00 pm | Jose Verges (Bioiberica Inc., Spain)
"Chondroitin Sulfate in Osteoarthritis: Pharmacological and Clinical Review" |
| 8:30 pm | Ulf Lindahl (University of Uppsala, Sweden)
"Heparan Sulfate Proteoglycans - Studies in Diversity" |
| 9:30 pm | Closing Remarks and Festivities |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
