| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Session: Rise of the Proteoglycans |
| Discussion Leader: Megan S. Lord (University of New South Wales, Sydney) |
| 3:45 pm - 4:15 pm | Pyong Woo Park (Children's Hospital, Harvard Medical School, Boston) |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Mechanosignaling in Development and Disease |
| Discussion Leaders: Brooke Farrugia (Graduate School of Biomedical Engineering, Australia) and Varun Krishnamurthy (Rice University, Houston, Texas) |
| 7:30 pm - 7:50 pm | Megan S. Lord (University of New South Wales, Sydney)
"Sulfation of the Chondroitin Sulfate Chain of Inter-α-Trypsin Inhibitor Controls the Formation of Hyaluronan-Heavy Chain Complexes: Implications for Functional Changes During Arthritis" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Beata Filipek-Gorniok (Uppsala University, Sweden)
"The Ndst Gene Family in Zebrafish: Role of Ndst1b in Pharyngeal Arch Formation" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Varun Krishnamurthy (Rice University, Houston, Texas)
"Inhibition of Complementary TGF-β Pathways Differentially Regulate Glycosaminoglycan Homeostasis in Mechanosensitive Aortic Valve Interstitial Cells" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Marissa Maciej (University of Manchester, United Kingdom)
"Inhibition of HS and Not CS by a Novel Competitive Inhibitor Displays Phenotype Similarities to Hereditary Multiple Exotoses in Xenopus" |
| 9:20 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 10:20 am | Signaling Through the Sugar |
| Discussion Leaders: Marissa Maciej (University of Manchester, UK) and Paul Keire (Benaroya Research Institute, Seattle, Washington) |
| 9:00 am - 9:15 am | Zehra Firat (Amkara University, Turkey)
"Global ADAMTS and TIMP Profiling in Diabetic Nephropathy Formation Reveals Deregulated Matrix Proteinaises in Diabetic Mice" |
| 9:15 am - 9:20 am | Discussion |
| 9:20 am - 9:35 am | Tabea Dierker (Uppsala University, Sweden)
"Unexpected Sulfation of Chondroitin in C. elegans" |
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 9:55 am | Brooke Farrugia (Graduate School of Biomedical Engineering, Australia)
"Glycosaminoglycans Modulate the Response of Inflammatory Cells to Implanted Materials" |
| 9:55 am - 10:10 am | Discussion |
| 10:10 am - 10:15 am | Aurijit Sarkar (Virginia Commonwealth University, Richmond, Virginia)
"Glycosaminoglycan-Protein Binding Specificity Constitutes More Than Arg/Lys-Sulfate Interactions" |
| 10:15 am - 10:20 am | Discussion |
| 10:20 am - 11:00 am | Mentorship Component: Grantsmanship and Writing Seminar |
| William C. Parks (Cedars-Sinai Medical Center, Seattle, Washington) |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:45 pm | The Instructive Matrix: Microenvironmental Cues |
| Discussion Leaders: Tabea Dierker (Uppsala University, Sweden) and Aurijit Sarkar (Virginia Commonwealth University, Richmond, Virginia) |
| 1:30 pm - 1:50 pm | Annabel Torres (Thomas Jefferson University, Philadelphia, Pennsylvania)
"Decorin Induces Autophagy in Endothelial Cells by Activating the Peg3/Beclin 1 Axis" |
| 1:50 pm - 1:55 pm | Discussion |
| 1:55 pm - 2:15 pm | Elisa Migliorini (University of Grenoble Alpes, France)
"Morphogens Crosslink Heparan Sulfate" |
| 2:15 pm - 2:20 pm | Discussion |
| 2:20 pm - 2:40 pm | Paul Keire (Benaroya Research Institute, Seattle, Washington)
"Versican and Cancer: Role in the Development of Leiomyosarcoma" |
| 2:40 pm - 2:45 pm | Discussion |
| 2:45 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
