Saturday |
2:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | Keynote Session: Small Proteoglycans |
| Discussion Leaders: Anthony Day (University of Manchester, United Kingdom) and Velina Bachvarova (University of Duisburg-Essen, Germany) |
3:45 pm - 4:15 pm | Marian Young (National Institutes of Health, USA) "Small Proteoglycans: Versatile Regulators of Bone Formation, Function and Repair" |
4:15 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | The Good and Bad of Proteoglycans: Effects in Developmental Processes and Disease Progression |
| Discussion Leaders: Shyam Bandari (University of Alabama at Birmingham, USA) and Rogier Reijmers (VU University Medical Center Amsterdam, The Netherlands) |
7:30 pm - 7:45 pm | Hannah Clarke (University of Liverpool, United Kingdom) "Altered Heparan Sulfate in Ageing and Dementia: A Potential Axis for the Dysregulation of BACE-1 in Alzheimer's Disease" |
7:45 pm - 7:50 pm | Discussion |
7:50 pm - 8:05 pm | Vivien Coulson-Thomas (University of Houston, USA) "Heparan Sulfate Regulates Hair Follicle Development" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:25 pm | Laura Ferreras (Institute of Cellular Medicine, Newcastle University, United Kingdom) "Investigating the Role of Heparan Sulfate 3-O Sulfotransferases in Renal Fibrosis" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:45 pm | Fengying Tang (University of New South Wales, Australia) "The Roles of CSPG4 and Perlecan in Cancer, Potential Targets for Drug Therapy" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:05 pm | Yeojung Kim (Cleveland Clinic Lerner Research Institute, USA) "Hyaluronan 35 kDa Treatment Induces Epithelial Tight Junction Protein ZO-1 In Vivo and May Be a Mechanism of Protection in Mice from Citrobacter Infection" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Aravind Sivakumar (Cornell University, USA) "Hyaluronan Synthesis Provides a Mechanism for Asymmetric Gut and Vascular Morphogenesis" |
9:25 pm - 9:30 pm | Discussion |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | How Proteoglycans Affect Cell Signaling / Structure-Function Correlations in the Extracellular
Matrix |
| Discussion Leaders: Andrew Hamilton (Uppsala University, Sweden) and Sarah Taylor (University of Liverpool, United Kingdom) |
9:00 am - 9:15 am | Oleksandr Nychyk (UCL Institute of Child Health, University College London, United Kingdom) "The Role of Proteoglycans in the Initiation of Neural Tube Closure" |
9:15 am - 9:20 am | Discussion |
9:20 am - 9:35 am | Sarvenaz Sarabipour (Johns Hopkins University, USA) "HSPG Allosterically Regulate FGF-FGFR Interactions" |
9:35 am - 9:40 am | Discussion |
9:40 am - 9:55 am | Rachel Ghadiali (University of Liverpool, United Kingdom) "Dynamic Changes in Heparan Sulfate During Muscle Differentiation and Ageing Are Associated with Regulation of Myoblast Cell Fate and FGF2 Signalling" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:15 am | Nehru Viji Sankaranarayanan (Virginia Commonwealth University, USA) "Computational Identification of Preferred Molecular Targets of Non-Saccharide Glycosaminoglycan Mimetics that Selectively Inhibit Cancer Stem Cell Growth" |
10:15 am - 10:20 am | Discussion |
10:20 am - 10:35 am | Jelena Rnjak-Kovacina (University of New South Wales, Australia) "Biomimetic Approaches Toward Silk Biomaterial Vascularisation Using Perlecan" |
10:35 am - 10:40 am | Discussion |
10:40 am - 10:55 am | Heather Davies (CNRS, France) "Cell Homing at the Blood Vessel Wall – Biomechanical vs Biochemical Controls" |
10:55 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Mentorship Component: From Bench Work to High Impact Publishing |
| Discussion Leaders: Rachel Ghadiali (University of Liverpool, United Kingdom) and Aaron Petrey (Cleveland Clinic, USA) |
1:30 pm - 1:50 pm | Jeffrey Esko (University of California, San Diego, USA) "How to Be Mensch at the Bench" |
1:50 pm - 2:00 pm | Discussion |
2:00 pm - 2:20 pm | Randy Schekman (University of California, Berkeley, USA) "How to Publish Science with Impact" |
2:20 pm - 2:30 pm | Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |