Sunday |
4:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Genomic Architecture of Complex Traits - Uncovering Missing Heritability |
| Discussion Leader: Ed Buckler (Cornell University Institute for Genomic Diversity, USA) |
7:40 pm - 7:50 pm | Introduction by Discussion Leader |
7:50 pm - 8:20 pm | Alkes Price (Harvard School of Public Health, USA) "Functional Interpretation of Hidden Heritability of Complex Traits" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:45 pm | Vineeta Agarwala (Broad Institute, USA) "A Quantitative Population Genetic Framework to Constrain the Range of Genetic Architectures Underlying Complex Human Traits" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Jian Yang (The University of Queensland, Australia) "Estimating Dominance Variance for Human Complex Traits Using Genome-Wide SNPs" |
9:20 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | From Correlation to Causation - Identifying Causative Variants Underlying Complex Traits |
| Discussion Leader: Manolis Dermitzakis (University of Geneva Medical School, Switzerland) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:40 am | James Holland (USDA-ARS / North Carolina State University, USA) "GWAS and Genomic Prediction in Maize" |
9:40 am - 9:55 am | Discussion |
9:55 am - 10:25 am | Hailiang Huang (Massachusetts General Hospital, USA) "Fine Mapping of Inflammatory Bowel Disease Risk Loci Using Immunochip" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:35 am | Gil McVean (University of Oxford, United Kingdom) "Fine-Mapping the Genetic and Mechanistic Basis of Risk of Multiple Sclerosis" |
11:35 am - 11:50 am | Discussion |
11:50 am - 12:20 pm | Manolis Dermitzakis (University of Geneva Medical School, Switzerland) "Population and Personalized Genomics for Human Biology" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | From Correlation to Causation - Identifying Causative Genes Underlying Complex Traits |
| Discussion Leader: Manolis Dermitzakis (University of Geneva Medical School, Switzerland) |
6:00 pm - 6:10 pm | Introduction by Discussion Leader |
6:10 pm - 6:40 pm | Jonathan Pritchard (Stanford University, USA) "Effects of Regulatory Variation from Chromatin to Proteins to Complex Traits" |
6:40 pm - 6:55 pm | Discussion |
6:55 pm - 7:25 pm | Michael Calderwood (Dana Farber Cancer Institute, USA) "Interactome Networks and Human Disease" |
7:25 pm - 7:40 pm | Discussion |
7:40 pm - 8:00 pm | General Discussion |
8:00 pm | Dinner |
Tuesday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | From Correlation to Causation - Identifying Networks Underlying Complex Traits |
| Discussion Leader: Ann Stapleton (University of North Carolina at Wilmington, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:40 am | Stig Omholt (Norwegian University of Life Sciences (NMBU), Norway) "Causally Cohesive Genotype-Phenotype Modelling" |
9:40 am - 9:55 am | Discussion |
9:55 am - 10:25 am | Ines Thiele (Luxembourg Centre for Systems Biomedicine, Luxembourg) "Investigation of Host-Microbe Interactions Using Computational Modeling" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:20 am | Na Cai (Wellcome Trust Centre for Human Genetics, United Kingdom) "The Mitochondria Genome's Response to Stress" |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:45 am | Lior David (The Hebrew University of Jerusalem, Israel) "Epistatic Interactions Hide and Change the Additive Contribution of QTLs and QTGs to Growth at High Temperature of Yeast" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:20 pm | Guilherme Rosa (University of Wisconsin, USA) "Modeling Networks for Prediction and Causal Inference" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | Population Genomics of Complex Traits |
| Discussion Leader: Bruce Walsh (University of Arizona, USA) |
6:00 pm - 6:10 pm | Introduction by Discussion Leader |
6:10 pm - 6:40 pm | Piter Bijma (Wageningen University, The Netherlands) "Social Genetics: Theoretical Foundations, Empirical Results and Future Challenges" |
6:40 pm - 6:55 pm | Discussion |
6:55 pm - 7:10 pm | Mashaal Sohail (Harvard University, USA) "Synergistic Epistasis in the Human Genome" |
7:10 pm - 7:15 pm | Discussion |
7:15 pm - 7:45 pm | Molly Przeworski (Columbia University, USA) "An Evolutionary Perspective on Human Germline Mutation" |
7:45 pm - 8:00 pm | Discussion |
8:00 pm | Dinner |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Evolutionary Genomics of Complex Traits |
| Discussion Leader: Bruce Walsh (University of Arizona, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:40 am | Leif Andersson (Uppsala University, Sweden) "Population Structure and Genetic Adaptation in Atlantic Herring Explored Using Whole Genome Resequencing and Experimental Pedigrees" |
9:40 am - 9:55 am | Discussion |
9:55 am - 10:25 am | Kathleen Donohue (Duke University, USA) "Genetic Variation in Seed Dormancy and Annual Plant Life Cycles" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:35 am | Peter Andolfatto (Princeton University, USA) "Admixture Mapping Reveals Genetic Incompatibilities and Genes Underlying Sexually Selected Traits in Xiphophorus Fish" |
11:35 am - 11:50 am | Discussion |
11:50 am - 12:20 pm | David Stern (Howard Hughes Medical Institute, USA) "The Genetic Causes of Courtship Behavior Evolution in the Genus Drosophila" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | Genomics of Host Pathogen Interactions |
| Discussion Leader: Daniel Pomp (University of North Carolina, School of Medicine, USA) |
6:00 pm - 6:10 pm | Introduction by Discussion Leader |
6:10 pm - 6:40 pm | Jeroen Raes (University of Leuven, Belgium) "Studying the Human Microbiome Using Metagenomics" |
6:40 pm - 6:55 pm | Discussion |
6:55 pm - 7:10 pm | Andrea Doeschl-Wilson (Roslin Institute, United Kingdom) "Do Genetic Superspreaders of Infections Exist and How to Identify Them?" |
7:10 pm - 7:15 pm | Discussion |
7:15 pm - 7:45 pm | Ran Blekhman (University of Minnesota, USA) "Genomics of Host-Microbe Interactions in the Tumor Microenvironment" |
7:45 pm - 8:00 pm | Discussion |
8:00 pm | Dinner |
Thursday |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
9:00 am - 12:30 pm | Epigenomics of Complex Traits |
| Discussion Leader: Vincent Colot (Institut de Biologie de l'Ecole Normale Supérieure, France) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:40 am | Richard Mott (Wellcome Trust Centre for Human Genetics, United Kingdom) "Epigenetics and Complex Traits" |
9:40 am - 9:55 am | Discussion |
9:55 am - 10:25 am | Erik Miska (University of Cambridge, United Kingdom) "The Impact of Transgenerational Epigenetic Inheritance in Nematodes" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:35 am | Frank Johannes (University of Groningen, The Netherlands) "In Search for the Epigenetic Basis of Complex Traits" |
11:35 am - 11:50 am | Discussion |
11:50 am - 12:20 pm | Allan McRae (Queensland Brain Institute, Australia) "Genetic and Environmental Control of DNA Methylation" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | Translational Genomics for Complex Traits |
| Discussion Leader: Chris Schoen (Technische Universitat Munchen, Germany) |
6:00 pm - 6:10 pm | Introduction by Discussion Leader |
6:10 pm - 6:40 pm | Mike Goddard (University of Melbourne, Australia) "Integrated Prediction of Phenotype and Mapping of Causal Variants" |
6:40 pm - 6:50 pm | Discussion |
6:50 pm - 7:10 pm | Laurence Moreau (Institut National de la Recherche Agronomique (INRA), France) "Optimizing the Calibration Population for Genomic Selection - Application in Maize" |
7:10 pm - 7:20 pm | Discussion |
7:20 pm - 7:50 pm | Atul Butte (Stanford University School of Medicine, USA) "Clinical Interpretation of Individuals and Populations Presenting with Whole Genome Sequences" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm | Dinner |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |