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Quantitative Genetics and Genomics

Gordon Research Conference

Leveraging High-Throughput Phenotyping Techniques to Study Complex Traits

February 12 - 17, 2023

Chair Guilherme J.M. Rosa

Vice Chairs Josephine M. Pemberton and Na Cai

Four Points Sheraton / Holiday Inn Express

1050 Schooner Drive

Ventura, California, United States

Venue and Travel Information

Conference Description

The Quantitative Genetics and Genomics GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

Related Meeting

This GRC will be held in conjunction with the "Quantitative Genetics and Genomics" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Conference Program

Sunday
2:00 pm - 9:00 pm	Arrival and Check-in
6:00 pm - 7:00 pm	Dinner
7:30 pm - 7:40 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm	Genetic Architecture of Quantitative Traits Discussion Leader: Jack Dekkers (Iowa State University, United States)
7:40 pm - 7:55 pm	Introduction by Discussion Leader
7:55 pm - 8:25 pm	Joseph Gage (NCSU, United States) "Regulatory Variation in Upstream Open Reading Frames Influences Quantitative Traits"
8:25 pm - 8:40 pm	Discussion
8:40 pm - 9:10 pm	Gustavo de los Campos (Michigan State University, United States) "Fine Mapping and Accurate Prediction of Complex Human Traits Using Ultra-High Density Genotypes and Biobank-Sized Data"
9:10 pm - 9:25 pm	Discussion
9:25 pm - 9:30 pm	General Discussion
Monday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Group Photo
9:00 am - 12:30 pm	Prediction of Complex Traits Discussion Leader: Vivian Breen (Cobb, United States)
9:00 am - 9:15 am	Introduction by Discussion Leader
9:15 am - 9:45 am	Miguel Perez-Enciso (Corteva, United States) "Beyond Genomic Prediction: Predicting Highly Multidimensional Objects"
9:45 am - 10:00 am	Discussion
10:00 am - 10:15 am	Madison Henniger (University of Tennessee - Knoxville, United States) "Uncovering Host Genetic Control of the Rumen Microbiome"
10:15 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:20 am	Daniela Lourenco (University of Georgia, United States) "Decoding Genomic Predictions in Large Populations"
11:20 am - 11:35 am	Discussion
11:35 am - 12:05 pm	Charlie Messina (University of Florida, United States) "Fusing Symbolic Crop Models and Sub-symbolic AI to Augment Predictive Breeding"
12:05 pm - 12:20 pm	Discussion
12:20 pm - 12:30 pm	General Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
3:00 pm - 4:00 pm	The GRC Power Hour™ The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring. Organizer: Rita Mumm (University of Illinois, United States)
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Epigenetic Variation Discussion Leader: Dirk-Jan de Koning (Swedish University of Agricultural Sciences, Sweden)
7:30 pm - 7:45 pm	Introduction by Discussion Leader
7:45 pm - 8:15 pm	Hasan Khatib (The University of Wisconsin-Madison, United States) "Gene-environment vs Epigene-Environment Interactions"
8:15 pm - 8:30 pm	Discussion
8:30 pm - 9:00 pm	Nathan Springer (Bayer Crop Sciences / University of Minnesota, United States) "Transposon Elements as Unstable Influences on Gene Expression"
9:00 pm - 9:15 pm	Discussion
9:15 pm - 9:30 pm	General Discussion
Tuesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Evolution of Quantitative Traits Discussion Leader: Bruce Walsh (University of Arizona, United States)
9:00 am - 9:15 am	Introduction by Discussion Leader
9:15 am - 9:45 am	Matthew Hufford (Ecology, Evolution, and Organismal Biology Department, Iowa State University, United States) "Comparative Genomic Analysis of Maize and Its Wild Relatives to Assess Evolution and Adaptation"
9:45 am - 10:00 am	Discussion
10:00 am - 10:15 am	Clara Polzer (Technical University of Munich, Germany) "A Rapid Cycling Selection Experiment in Maize Landraces"
10:15 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:05 am	Zhi Loh (School of Environmental and Rural Science, University of New England, Australia) "A Flexible, Semi-Parametric Algorithm for Estimation of Genetic Architecture Parameters"
11:05 am - 11:10 am	Discussion
11:10 am - 11:25 am	Alice Etourneau (INRAE, France) "Characterizing the Tecombination Landscape and its Genetic Architecture in Domestic Goat"
11:25 am - 11:30 am	Discussion
11:30 am - 12:00 pm	Suzanne McGaugh (University of Minnesota, United States) "Repeated Adaptation to Cave Environments Through De Novo Mutations and Standing Genetic Variation"
12:00 pm - 12:15 pm	Discussion
12:15 pm - 12:30 pm	General Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Selection and Breeding Strategies Discussion Leader: Aniek Bouwman (Wageningen University & Research, The Netherlands)
7:30 pm - 7:45 pm	Introduction by Discussion Leader
7:45 pm - 8:15 pm	Maria Martinez Castillero (Beta Bugs & Roslin Institute, United Kingdom) "Implementation of Genetics, Technology and Strategies for Black Soldier Fly Production"
8:15 pm - 8:30 pm	Discussion
8:30 pm - 9:00 pm	Edward Buckler (Agricultural Research Service, U.S. Department of Agriculture, United States) "The Nitrogen Problem: How Quantitative Genetics and Genomics Applied Across All Domains of Life Can Help Tackle Climate Change"
9:00 pm - 9:15 pm	Discussion
9:15 pm - 9:30 pm	General Discussion
Wednesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Health and Welfare Traits Discussion Leader: Andrea Doeschl-Wilson (Roslin Institute, University of Edinburgh & Swedish University of Agricultural Sciences, United Kingdom)
9:00 am - 9:15 am	Introduction by Discussion Leader
9:15 am - 9:45 am	Juan Steibel (Iowa State University, United States) "Genetics of Swine Behavior for Increased Animal Welfare and Productivity"
9:45 am - 10:00 am	Discussion
10:00 am - 10:15 am	Everest Castaneda (Baylor University, United States) "Network Enhanced Similarity Search Increases the Predictive Power of a Highly Heterogenous Network"
10:15 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:20 am	Gosia Trynka (Wellcome Sanger, United Kingdom) "Moving From GWAS Variants to Function in Immune Diseases"
11:20 am - 11:35 am	Discussion
11:35 am - 12:05 pm	Cassandra Spracklen (University of Massachusettts Amherst, United States) "In and Out of Context: Deciphering the Genetic and Genomic Architecture of Type 2 Diabetes"
12:05 pm - 12:20 pm	Discussion
12:20 pm - 12:30 pm	General Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Use of Functional Annotation Discussion Leader: Clare Gill (Texas A&M University, United States)
7:30 pm - 7:45 pm	Introduction by Discussion Leader
7:45 pm - 8:15 pm	Angela Cánovas (University of Guelph, Canada) "ARS-UCD1.2 or UMD3.1 Bovine Reference Genome? Evaluating Their Impact at Genome, Transcriptome and Methylome Level"
8:15 pm - 8:30 pm	Discussion
8:30 pm - 9:00 pm	David Houle (Florida State University, United States) "The Problem with Pleiotropy"
9:00 pm - 9:15 pm	Discussion
9:15 pm - 9:30 pm	General Discussion
Thursday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Business Meeting Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm	High-Throughput Phenotyping Discussion Leader: Alexander Lipka (University of Illinois at Urbana-Champaign, United States)
9:00 am - 9:15 am	Introduction by Discussion Leader
9:15 am - 9:45 am	Luiz Brito (Purdue University, United States) "Integrating Large-Scale Phenotyping and Quantitative Genomics to Address a Multifaceted Breeding Goal: Livestock Welfare and Resilience"
9:45 am - 10:00 am	Discussion
10:00 am - 10:15 am	Michelle Harwood (Ontario Institute for Cancer Research, Canada) "Increased Allele-specific Expression in Blood Can be Beneficial for Immune Response in Healthy Agers"
10:15 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:20 am	John McKay (Colorado State University, United States) "High Throughput Phenotyping Facilitates Understanding of GxE and Genetics of Adaptation to Variable Environments"
11:20 am - 11:35 am	Discussion
11:35 am - 12:05 pm	Emily Davenport (Pennsylvania State University, United States) "Using the Microbiome as a Proxy for Host Environmental Influences in GWAS"
12:05 pm - 12:20 pm	Discussion
12:20 pm - 12:30 pm	General Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Gene Mapping and Functional Genomics Discussion Leader: Ana Vazquez (Michigan State University (MSU), United States)
7:30 pm - 7:45 pm	Introduction by Discussion Leader
7:45 pm - 8:15 pm	Loic Yengo (The University of Queensland, Australia) "The Path to Mapping all Genetic Variation Associated with Human Height"
8:15 pm - 8:30 pm	Discussion
8:30 pm - 9:00 pm	Laura Raffield (University of North Carolina, Chapel Hill, United States) "Multi-Omic Data Integration to Link Variants to Function in Diverse Human Cohort Studies"
9:00 pm - 9:15 pm	Discussion
9:15 pm - 9:30 pm	General Discussion
Friday
7:30 am - 8:30 am	Breakfast
9:00 am	Departure

Contributors

Research reported in this publication was supported by the National Institutes of Health under Award Number R13HG012696. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Conference Links

Conference History Quantitative Genetics and Genomics (GRS)

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