Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Quantitative Genetics and the Search for the Missing Heritability: The Long (and Ongoing) Search for Quantitative Trait Variation
Discussion Leader: Ann Stapleton (University of North Carolina at Wilmington, USA)
3:45 pm - 4:15 pm
Bruce Walsh (University of Arizona, USA)
"Quantitative Genetics and the Search for the Missing Heritability: The Long (and Ongoing) Search for Quantitative Trait Variation"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Genetic Architecture
Discussion Leaders: Frank Albert (University of Minnesota, USA) and Julia Steinberg (Wellcome Trust Sanger Institute, United Kingdom)
7:30 pm - 7:45 pm
Christine O'Connor (University of Oregon, USA)
"Using Experimental Evolution and Next Generation Sequencing to Dissect the Genetic Architecture of Acute Stress Response in the Nematode Caenorhabditis remanei "
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Zoe Migicovsky (Dalhousie University, Canada)
"Quantifying the Genetic Basis of Leaf Shape in Apple"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Sarah Signor (University of Southern California, USA)
"Convergent Evolution of Male Specific Color Patterns in Drosophila "
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Franziska Kreuchwig (Max Delbrueck Center for Molecular Medicine (MDC), Helmholtz Association, Germany)
"Dissecting the Genetic Basis of Transcriptional and Translational Regulation in Heart Failure"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Gregory Keele (University of North Carolina at Chapel Hill, USA)
"Accounting for Haplotype Uncertainty in QTL Mapping of Multiparental Populations Using Multiple Imputation"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Optimization of the Genetic Diversity of a Sequenced Population to Improve Imputation Accuracy of Rare Variants"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Investigating the Role of Context / Mentorship Component: Panel Discussion
Discussion Leaders: Bruce Walsh (University of Arizona, USA) and Yvonne Wientjes (Wageningen University and Research, The Netherlands)
9:00 am - 9:15 am
Joseph Gage (University of Wisconsin-Madison, USA)
"Mapping Variants Associated with Phenotypic Stability in Maize"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Troy Rowan (University of Missouri, USA)
"Local Genetic Adaptation in United States Bos Taurus Cattle"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Jovana Marjanovic (Wageningen University, The Netherlands)
"Modelling the Co-Evolution of Indirect Genetic Effects and Inherited Variability"
9:55 am - 10:00 am
Discussion
10:00 am - 11:00 am
Panel Discussion
Keys to Success
Frank Albert (University of Minnesota, USA)
Natalia De Leon (University of Wisconsin-Madison, USA)
Michel Georges (University of Liege, Belgium)
Ann Stapleton (University of North Carolina at Wilmington, USA)
Bruce Walsh (University of Arizona, USA)
Nicolas Heslot (Limagrain, France)
Peter Visscher (University of Queensland, Australia)
Emma Huang (Janssen R&D, USA)
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Modelling Variability
Discussion Leaders: Natalia De Leon (University of Wisconsin-Madison, USA) and Wesley Crouse (University of North Carolina at Chapel Hill, USA)
1:30 pm - 1:45 pm
Michael Turchin (University of Chicago, USA)
"Bayesian Multivariate Re-Analysis of Large Genetic Studies Identifies Many Novel Associations"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Rachel Moore (Wellcome Trust Sanger Institute - EBI Single-Cell Genomics Centre, United Kingdom)
"TreeLMM: Modelling Heterogeneity of Genetic Effects"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Valerie Arboleda (University of California, Los Angeles, USA)
"Shared Genetic Basis of Complex and Rare Disease"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes