Sunday, January 24, 1999
4:00-6:00 pm |
Registration and reception |
- sponsors: Novartis & Roche/Boehringer Mannheim
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| 7:30-9:30 pm |
Diversity of editing systems |
- welcoming remarks and announcements
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- Larry Simpson, chair and short talk: "A second type of RNA editing in Leishmania mitochondria"
- Kazuko Nishikura: "RNA editing site selectivity of dsRNA adenosine deaminase gene family"
- Tom Innerarity: "The use of RNA editing in functional genomics"
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Monday, January 25, 1999
9:00 am-12:30 pm |
Evolution and genomic analysis |
- Rob Benne, chair and short talk: "Evolution of RNA editing in mitochondria of kinetoplastids"
- Maureen Hanson: "Plastid biology and cross-species editing"
- B. Franz Lang: "Evolution of mitochondrial tRNA editing in lower fungi and protists: Evidence for several independent origins"
- James McCloskey: "Phylogenetic relationships in modification patterns"
- Laura Landweber (short talk): "Decoupling the evolution of mixed types of RNA editing in myxomycetes"
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- 11:00 am - Group picture during break
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| 4:30-6:00 pm |
Poster session |
- presenters of ODD numbered posters should be in attendance
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| 7:30-9:30 pm |
Editing in the context of RNA synthesis and processing |
- Daniel Kolakofsky, chair and short talk: "The versatility of paramyxovirus RNA polymerase stuttering"
- Jonatha Gott: "RNA editing associated with transcription complexes from Physarum mitochondria"
- Ron Emeson: "ADAR2 auto-regulation: Another box of chocolates"
- Shula Michaeli (short talk): "The trypanosome signal recognition particle is comprised of two separate RNA molecules and its 7SL RNA undergoes a novel editing event"
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Tuesday, January 26, 1999
9:00 am-12:30 pm |
Mechanisms of editing: trans-acting factors |
- Barbara Sollner-Webb, chair and short talk: "Elucidating the determinants that direct U-deletional versus U-insertional RNA editing of trypanosomes"
- Pal Maliga: "Design of genetic screens to isolate mutations in plastid RNA editing"
- Andre Gerber: "Molecular characterization of tRNA-specific adenosine deaminases"
- Anuradha Mehta (short talk): " A sequence-specific RNA-binding protein complements apobec-1 to edit apolipoprotein-B mRNA"
- Jose Gualberto: "Cytidine deaminase genes and activities in higher plants"
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| 7:30-9:30 pm |
Mechanisms of editing: cis elements and new targets |
- Ralph Bock, chair and short talk: "RNA editing site recognition in plastids"
- Greg Connell: "A cis-acting A-U sequence element induces kinetoplastid U-insertions"
- Brenda Bass: "Substrates of adenosine deaminases that act on RNA"
- Tetsuro Hirose: "In vitro analysis of the roles and mechanism of RNA editing in chloroplasts "
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| Wednesday, January 27, 1999
9:00 am-12:30 pm |
Editing and modification of stable RNAs |
- Dennis Miller, chair and short talk: "Variation of insertional editing site location among rRNAs and tRNAs of the myxomycota"
- Mike Gray: "A novel nucleotide incorporation activity implicated in the editing of mitochondrial transfer RNAs in Acanthamoeba castellanii"
- Anita Hopper: "Subcellular distribution of eukaryotic tRNA modification isozymes; sorting information resides in domains missing from eubacteria and/or archaeal counterparts"
- Skip Fournier: "The small nucleolar RNAs: Small antisense RNA machines that guide rRNA maturation"
- Henri Grosjean: "RNA recognition by selected tRNA modification enzymes"
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| 4:30-6:00 pm |
Poster session |
- presenters of EVEN numbered posters should be in attendance
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| 7:30-9:30 pm |
Approaches to the study of editing |
- Alan Herbert, chair and short talk: "Structure/function studies on the Z-DNA binding domain of mammalian ADAR1"
- Steve Hajduk: "Identification of a novel RNA binding protein with repetitive domains which is required for RNA editing in trypanosomes"
- Liam Keegan (short talk): "A to I editing of tRNA and pre-mRNA in Drosophila melanogaster"
- Harold Smith: "What is the auxiliary protein requirement in ApoB mRNA editing and approaches in defining functional elements"
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- Business meeting / election of new chairs
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Thursday, January 28, 1999
9:00 am -12:30 pm |
Functional implications |
- Larry Chan, chair and short talk: "Auxiliary factors for apoB mRNA editing"
- Jane Petschek (short talk): "RNA Editing in Drosophila"
- Uli Goringer: "RNA-binding proteins as participants in the RNA editing reaction cycle in Trypanosoma brucei"
- Nick Davidson: "Novel functions of APOBEC1 in RNA metabolism"
- Miyoko Higuchi: "Rescue of epileptic, lethal ADAR2 deficient mice by GluR(R) alleles"
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| 5:00-7:30 pm |
Regulation and mechanism |
Donna Koslowsky, chair
- Ken Stuart: "The mechanism by which kinetoplastid mRNA editing specifies the number of uridylates"
- James Scott: "Do new forms of APOBEC exist in the genome?"
- Chuck Samuel (short talk): "Regulation of ADAR1 gene expression"
- Summary, Conference Co-chairs, Drs. Jonatha Gott and Maureen Hanson
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| 8:00 pm |
Dinner and presentation of awards for the RNA Society Poster Competition |
