| Sunday, January 21, 2001 |
| 4:00-6:00 p.m.: | Registration and reception |
| 7:30-9:30 p.m.: | Evolution of RNA Editing |
| 7:30-8:00 p.m.: | A. Stoltzfus, Chair
(Is RNA editing an evolutionary anomaly?) |
| 8:00-8:30 p.m.: | L.M. Rocha
(Simulations of RNA editing and the origin of codes) |
| 8:30-9:00 p.m.: | N.J. Savill
(Evolutionary implications of minicircle segregation in trypanosomatids: a random tale of minicircle segregation) |
| 9:00-9:30 p.m.: | L. Marechal-Drouard
(Editing of transfer RNA in higher plants mitochondria: function and evolution) |
| Monday, January 22, 2001 |
| 9:00-12:30 a.m.: | C-to-U editing of apolipoprotein B |
| 9:00-9:25 a.m.: | H.C. Smith, Chair
(Differential complexity in the assembly of editosomal proteins is a characteristic of their subcellular localization and function) |
| 9:25-9:55 a.m.: | J. Greeve
(Functional analysis of the APOBEC-1 stimulating protein ASP (ACF) in vitro and in vivo) |
| 9:55-10:25 a.m.: | BREAK/GROUP PICTURE |
| 10:25-11:00 a.m.: | D. Driscoll
(Editing of apolipoprotein-B mRNA by ACF and apobec-1) |
| 11:00-11:30 a.m.: | J. Scott
(The APOBEC gene family: new molecular targets) |
| 11:30-12:00 a.m.: | V. Blanc
(Regulation of apo B mRNA editing by novel RNA binding proteins) |
| 12:00-12:15 p.m.: | M. Muramatsu
(Class switch recombination and somatic hypermutation of 1g require AID, a potential RNA editing deaminase) |
| 12:15-12:30 p.m.: | M. Sowden
(Identification of rat p66/ACF as nuclear and cytoplasmic RNA binding phosphoprotein whose transcription is increased during fasting/refeeding) |
| 4:00-6:00 p.m.: | Poster Session
Presenters of odd numbered posters should be in attendance |
| 7:30-9:30 p.m.: | C-to-U editing in plants |
| 7:30-7:45 p.m.: | M.R. Hanson, Chair
(Cis-acting elements affecting chloroplast RNA editing) |
| 7:45-8:00 p.m.: | M. Reed
(In vivo analysis of cis-acting elements affecting editing at a tobacco rpoB sequence) |
| 8:00-8:30 p.m.: | Mike Mulligan / Dan Cho
(RNA Editing in mitochondria of the flowering plant Arabidopsis thaliana) |
| 8:30-9:00 p.m.: | Junichi Obokata
(In vitro analysis of editing in chloroplasts) |
| 9:00-9:30 p.m.: | R. Bock
(Factors for plastid RNA editing) |
| Tuesday, January 23, 2001 |
| 9:00-12:30 a.m.: | A-to-I editing (Session I) |
| 9:00-9:30 a.m.: | C.E. Samuel, Chair
(Regulation of ADAR1 expression and activity by cytokines and viruses) |
| 9:30-10:00 a.m.: | R. Emeson
(The specifics of ADAR2 overexpression) |
| 10:00-10:15 p.m.: | K. Gardiner
(Vertebrate A to I editase genes: insights from genomic analysis) |
| 10:15-10:45 a.m.: | B. Bass
(Adenosine deaminases that act on RNA and their double stranded RNA substrates) |
| 10:45-11:15 a.m.: | BREAK |
| 11:15-11:45 a.m.: | P. Seeburg
(ADAR-deficient mice: a genetic evaluation of A to I editing in mammals) |
| 11:45-12:15 a.m.: | M.A. O'Connell
(Regulation of ADAR activity in Drosophila melanogaster) |
| 12:15-12:30 p.m.: | Stefan Maas
(Protein interaction partners of ADARs) |
| 7:30-9:30 p.m.: | A-to-I editing (Session II) |
| 7:30-8:00 p.m.: | K. Nishikura, Chair
(A to I editing and mouse development) |
| 8:00-8:30 p.m.: | R.A. Reenan
(ADAR-mediated pre-RNA Editing in Drosophila) |
| 8:30-9:00 p.m.: | P.A. Beal
(Using nucleoside analogs to probe the mechanism of an RNA editing adenosine deaminase) |
| 9:00-9:15 p.m.: | Alexandre Araya
(RNA editing activity is associated with splicing factors in 1nRNP particles - the nuclear pre-mRNA processing machinery) |
| Wednesday, January 24, 2001 |
| 9:00-12:30 a.m.: | Guided and unguided nucleotide modifications of tRNA and rRNA |
| 9:00-9:15 a.m.: | H. Grosjean, Chair
(Various modes of RNA recognition by RNA modifying enzymes: differences and analogies with RNA recognition by selected RNA editing enzymes) |
| 9:15-9:45 a.m.: | T. Hirose
In vivo and in vitro analyses of the intron-encoded snoRNA synthesis |
| 9:45-10:15 a.m.: | Todd Lowe
(Hunting for methylation guide snoRNAs in complete metazoan genomes) |
| 10:15-10:45 a.m.: | BREAK |
| 10:45-11:15 a.m.: | Y-T Yu
Internal modification of U2 snRNA occurs in nucleoli of Xenopus oocytes |
| 11:15-11:45 a.m.: | M. Fournier
(Eukaryotic Ribosome function can be impaired by under- or overmodification of the peptidyl transferase center by snoRNPs) |
| 11:45-12:15 p.m.: | P. Crain
(Mitochondrial editing and modification of the imported tRNAtrp in Leishmania) |
| 12:15-12:30 | D. Lazinski
(Amber/W site editing by ADAR1 and ADAR2) |
| 4:00-6:00 p.m.: | Poster Session
Presenters of even numbered posters should be in attendance |
| 7:30-9:30 p.m.: | tRNA editing |
| 7:30-7:45 p.m.: | J. Alfonzo
(A single base pair flip abrogates C to U editing of the mitochondria-imported tRNATrp in Leishmania tarentolae) |
| 7:45-8:00 p.m.: | M. Schaub
(The yeast tRNA:A34 deminase: identification of amino acids critical for activity, tRNA binding and Tad2p/Tad3p heterodimer formation) |
| 8:00-8:30 p.m.: | Jeannette Wolf
(tRNA-specific adenosine deaminases from bacteria, yeast and man) |
| 8:30-9:00 p.m.: | M. Morl
(Editing and repair of mitochondrial tRNAs in metazoans) |
| 9:00-9:30 p.m.: | M. Gray (Mitochondrial Transfer RNA Editing in Amoeboid Protozoa) |
| 10:00 p.m.: | Business meeting: elections of new chairs |
| Thursday, January 25, 2001 |
| 9:00-12:30 a.m.: | Uridine insertion/deletion editing |
| 9:00-9:15 a.m.: | R. Benne, Chair
(gRNA-binding proteins from C. fasciculata) |
| 9:15-9:45 a.m.: | D. Maslov
(Translation systems in the kinetoplast of Leishmania) |
| 9:45-10:15 a.m.: | Uli Goringer (Guide RNA binding protein gBP21 is a matchmaker type RNA annealing factor) |
| 10:15-10:45 a.m.: | BREAK |
| 10:45-11:15 a.m.: | K. Stuart
(Composition of the RNA editing complex of Trypanosoma brucei) |
| 11:15-11:45 a.m.: | L. Read
(Macromolecular interactions involving the gRNA binding protein, RPB16) |
| 11:45-12:15 p.m.: | D.J. Koslowsky
(Implications of RNA structure and sequence on gRNA/mRNA interactions in kinetoplastid RNA editing) |
| 12:15-12:30 p.m.: | D. Scadden
(Specific cleavage of hyper-edited dsRNA) |
| 6:00 p.m. | Dinner and presentation of awards |
| 7:30 p.m-9:30 p.m..: | Uridine insertion/deletion editing, cytidine insertion and viral editing |
| 7:30-7:50 p.m.: | B. Sollner-Webb, Chair
(Cloning and characterization of the protein components of the RNA editing complex and differences between U insertion and U deletion editing) |
| 7:50-8:15 p.m.: | S. Hajduk
(Mitochondrial RNA ligases: Mechanistic and evolutionary significance of these enzymes in kinetoplastid RNA editing) |
| 8:15-8:40 p.m.: | L. Simpson
(Isolation and characterization of the mitochondrial 3’ terminal uridylyl transferase, a 3' U-specific exonuclease and two RNA chaperone proteins from Leishmania and Trypanosoma) |
| 8:40-9:05 p.m.: | J. Gott
(Cis-acting elements influencing RNA editing in Physarum)
|
| 9:05-9:30 p.m.: | D. Kolakofsky
(Cis-acting sequences and the control of paramyxovirus mRNA editing/stuttering) |
| 9:30- | Presentation of Awards |
