Biological Mechanisms and Applications of RNA Editing and Modifications

The GRC on RNA Editing is the only international meeting dedicated exclusively to RNA editing and RNA modifications. The 2025 meeting is subtitled "Biological Mechanisms and Applications of RNA Editing and Modification" and will showcase the breadth of the newest advancements in this rapidly growing field. RNA editing and modification are highly abundant phenomena, occurring in almost all RNAs, in all cells, and in all organisms. These relatively simple molecular events carry far-reaching biological consequences, and our knowledge about them is expanding quickly. Importantly, many biological roles of RNA editing and modification are actively being uncovered, and these range from the control of gene expression, adaptation to stress, viral, microbial and parasitic infectivity, organismal development, brain function, innate and adaptive immunity, inherited diseases, cancer and more. Based on a strong foundation in mechanistic and functional investigations on RNA editing and modification enzymes, our research field has now entered a new and exciting era where a variety of applications are emerging that utilize RNA editing and modifications as tools for research and health. The 2025 meeting will showcase these novel applications in the areas of therapeutics that alter the transcriptome and proteome, more effective mRNA vaccines, among others. A goal of this meeting is to facilitate the translation of academic discoveries in the area of RNA editing and modification into platforms that advance biotechnology and health. Overall, the 2025 GRC on RNA Editing will accelerate discovery by inspiring research into biological mechanisms, by fostering knowledge translation, by building a strong, diverse, and inclusive community and, most importantly, by developing the next generation of creative scientists.