| SATURDAY |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Speaker |
| 3:45 pm - 4:15 pm | Pat Limbach (University of Cincinnati)
"RNA spell checking: Approaches for identifying editing and modification sites" |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Biological roles of editing and modification |
| Discussion Leaders: Ashani Kuttan (University of Utah) and Gilad Silberberg (Stockholm University) |
| 7:30 pm - 7:45 pm | Bryan Warf (University of Utah)
"ADARs affect small RNA biogenesis in C. elegans" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Liu Yang (Institute for Nutritional Sciences, Shanghai)
"The cellular function and regulation of RNA editing enzyme ADAR2 in pancreatic beta-cells" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Ylva Ekdahl (Stockholm University)
"A-to-I editing of microRNAs in the mammalian brain increase during development" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Bhalchandra S. Rao (Ohio State University)
"Novel repair activities and regulation of Thg1 enzymes: New frontiers for 3'-5' nucleotide additions" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | Maria Werner (International Institute of Molecular and Cell Biology, Warsaw)
"Identification and characterization of human mRNA cap2 methyltransferase" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Isao Masuda (University of Tokyo)
"Mitochondrial gene expression of a parasitic protist Perkinsus requires extensive frameshift at all AGG and CCC codons" |
| 9:25 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Structure, function and specificity of editing/modification systems |
| Discussion Leader: Brian Smith (Ohio State University) and Jeremy Wilusz (Massachusetts Institute of Technology) |
| 9:00 am - 9:15 am | Rena A. Goodman (University of California, Davis)
"Investigation of a new A-to-I editing site: Structural probing and functional consequences" |
| 9:15 am - 9:20 am | Discussion |
| 9:20 am - 9:35 am | Kimberly Prohaska (University of Rochester)
"Novel research tools for dissociating RNA from APOBEC3G" |
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 9:55 am | Jessica L. Spears (Ohio State University)
"Trypanosoma brucei ADAT2/3 tRNA deaminase: Conserved active site residues, unique active site architecture" |
| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 10:15 am | Michael L. Hayes (University of California, Irvine)
"The evolution of editing PPRs reveals highly conserved structural motifs that suggest a mechanism for RNA binding and substrate specificity" |
| 10:15 am - 10:20 am | Discussion |
| 10:20 am - 10:35 am | Leila Rieder (Brown University)
"A tale of two (or three, or four) structures: In vivo demonstration of long-range secondary and tertiary RNA structures directing ADAR modification" |
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 10:55 am | Takanori Yano (University of Tokyo)
"Functional analysis of A-to-I editing in the intronic region of human mRNAs" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 3:00 pm | Bioinfomatic and evolutionary analysis of editing and modification |
| Discussion Leader: Dylan Dupuis (Lehigh University) and Michael Guy (University of Rochester) |
| 1:30 pm - 1:45 pm | Shahar Alon (Tel Aviv University)
"Systematic identification of A-to-I editing in mature miRNAs" |
| 1:45 pm - 1:50 pm | Discussion |
| 1:50 pm - 2:05 pm | Aaron Yap (University of Western Australia)
"Surveying the A. thaliana editotype" |
| 2:05 pm - 2:10 pm | Discussion |
| 2:10 pm - 2:25 pm | Claire Hamilton (Rockefeller University)
"Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA editing targets in transcript 3'UTRs" |
| 2:25 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
