Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Novel Treatment/Preventive Aspects for Salivary Gland Dysfunction
Discussion Leader: Mariane Martinez (Rice University, USA)
3:45 pm - 4:15 pm
Olga Baker (University of Utah School of Dentistry, USA)
"Resolution of Salivary Gland Inflammation"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Development/Regeneration and Progenitor Cells
Discussion Leader: Christina Maruyama (University of Utah, USA)
7:30 pm - 7:45 pm
Harleen Athwal (University of Michigan School of Dentsitry, USA)
"The Role of SOX10 in Epithelial KIT+ Salivary Gland Stem/Progenitor cells"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Kara DeSantis (University at Albany, SUNY, USA)
"Retinoic Acid Receptor Isoforms Reciprocally Control Proliferation of Cytokeratin 5-Positive Salivary Epithelial Cells"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Aaron Mattingly (University of California, San Francisco, USA)
"Neuregulin-1/ERBB3 Signaling Is Essential for Mouse Salivary Gland Development and Acinar Cell Formation"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Sarah Pringle (University of Groningen, The Netherlands)
"Exhaustion of Salivary Gland Stem Cells Causes Hyposalivation in Primary Sjogren's Syndrome"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Cecilia Rocchi (University Medical Center Groningen, The Netherlands)
"Influence of Hippo Pathway on Salivary Gland Stem Cells Regenerative Potential"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Lionel Berthoin (University of California, San Francisco, USA)
"Deciphering the Mechanisms of Aging in the Salivary Gland"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Disease and Tissue Engineering Approaches
Discussion Leader: Tathyane Teshima (University of Sao Paulo, Brazil)
9:00 am - 9:15 am
Ana Caroline Costa da Silva (National Institutes of Health, USA)
"Immunobiology of Labial Minor Salivary Gland Injury in the Pathogenesis of Oral cGVHD"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Kimberly Jasmer-McDonald (University of Missouri, USA)
"Exploring the Role of P2Y2 Nucleotide Receptors (P2Y2Rs) in a Novel Autoimmune Mouse Model of Sjögren's Syndrome"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Kihoon Nam (University of Utah School of Dentistry, USA)
"L1 Peptide-Conjugated Fibrin Hydrogels Promote Salivary Gland Regeneration"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Abeer Shaalan (King's College London, United Kingdom)
"TLR3 Mediated Injury and Dysfunction in Salivary Glands"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Jomy Varghese (University of Rochester, USA)
"Tracking siRNA-Treated Submandibular Gland Cell Fate and Function via Co-Delivery of 4-Hydroxytamoxifen"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Danielle Wu (Rice University, USA)
"Differentiation of Salivary Human Stem/Progenitor Cells and Pedigrees in Bioactive Hydrogels"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Discussion Panel
A panel of three senior scientists in the field, Olga Baker (University of Utah), Rachel Ettinger (MedImmune) and Sarah Knox (University of California, San Francisco), will briefly introduce themselves and their career trajectories, followed by a chance for the GRS attendees to ask the panel questions regarding "How to balance research for either an academic or industry career".
Discussion Leader: Elaine Emmerson (University of Edinburgh, United Kingdom)
1:30 pm - 2:30 pm
Panel Discussion
Balancing Industry and Academia
Olga Baker (University of Utah School of Dentistry, USA)
Rachel Ettinger (MedImmune, USA)
Sarah Knox (UCSF, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes