Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Intersections of Secretory Dysfunction and Disease
Discussion Leader: Aaron Mattingly (University of California, San Francisco, USA)
3:45 pm - 4:20 pm
Blake Warner (National Institute of Dental and Craniofacial Research, NIH, USA)
"Xerostomia as a Complication of Cancer Immune Checkpoint Inhibition"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Insights into Inflammation and Disease
Discussion Leaders: Spencer Dean (School of Dentistry, University of Utah, USA) and Kimberly Jasmer-McDonald (University of Missouri, USA)
7:30 pm - 7:45 pm
Xiaoyan Wang (University Medical Center Groningen, The Netherlands)
"Senescence Markers: New Promising Early Diagnostic Biomarkers for Primary Sjögren's Syndrome?"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Jeremy Kiripolsky (University at Buffalo, SUNY, USA)
"Activation of Multiple Myd88-Dependent Tlr Signaling Pathways Mediate Salivary Gland Inflammation in a Mouse Model of Primary Sjögren's Syndrome"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Adam Martin (University of Missouri, USA)
"Loss of the P2X7 Receptor for Extracellular ATP Increases Lymphocytic Infiltration of Submandibular Glands in Aging Female Mice"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Ana Caroline Costa da Silva (National Institutes of Health, USA)
"Damage-Associated Molecular Pattern (DAMP) Signaling: A Possible Trigger for Salivary Gland Graft-Versus-Host Disease?"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Esra Amoura (School of Clinical Dentistry, University of Sheffield, United Kingdom)
"The Role of CRTC1-MAML2 Fusion Protein in Mucoepidermoid Carcinoma"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Alison May (University of California, San Francisco, USA)
"CFTR Acts as an Essential Regulator of Exocrine Gland Morphogenesis"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Progenitor Cells, Programming, Regeneration and Secretion
Discussion Leaders: Isabelle Lombaert (University of Michigan, USA) and John McKendrick (University of Edinburgh, United Kingdom)
9:00 am - 9:15 am
Paola Serrano Martinez (University Medical Center Groningen / University of Groningen, The Netherlands)
"Interaction Between β-Adrenergic and the Notch Signaling in Medication-Induced Hyposalivation"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Harim Santos (University of Utah, USA)
"Laminin 111 Peptides Improve Par-C10 Cell Attachment and Organization"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Nicholas Moskwa (University at Albany, SUNY, USA)
"Collaborative Mesenchyme Is Necessary for Salivary Gland Proacinar Epithelial Organoid Differentiation"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Callie Brown (University of Utah, USA)
"Synergistic Effects of Laminin-1 Peptides, VEGF and FGF9 on Salivary Gland Regeneration"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Marie Saitou (University at Buffalo, SUNY, USA)
"Comparative RNA-Seq Sheds Light on Functional and Evolutionary Differentiation of Human Major Salivary Glands"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Danielle Wu (University of Texas Health Science Center at Houston, USA)
"Building a 3D Salivary Tissue (3D-ST) Replacement for Patients with Xerostomia"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Exploring Career Paths in Science
Discussion Leader: Sarah Pringle (University of Groningen, The Netherlands)
1:30 pm - 2:30 pm
Panel Discussion
Exploring Career Paths in Science: Academia, Industry and Scientific Writing
Agathe Bourgogne (Bellicum Pharmaceutical, Inc., USA)
Isabelle Lombaert (University of Michigan, USA)
Susan Marriott (BioScience Writers, LLC, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
