| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 4:30 pm - 6:00 pm | Reception |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Opening of Meeting |
| David Castle (Univ. of VA), Discussion Leader
Welcome and Introduction |
| Elisabeth Knust (Universitat Dusseldorf, Germany), Keynote Speaker
Molecular basis of epithelial morphogenesis |
| Discussion |
| David Quissell (Univ Colorado Hlth Sci), Discussion Leader
Introduction to Michael Humphreys-Beher Memorial Lecture |
| Antony Rosen (Johns Hopkins), Keynote Speaker
Sjogren's Syndrome, basic to clinical |
| Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Glandular Development |
| Discussion Leaders: Deborah Andrew (Johns Hopkins) & Ed Gresik (CUNY Med) |
| Monn Monn Myat (Johns Hopkins)
Insect salivary gland morphogenesis |
| Discussion |
| 10:00 am | Group Photo and Coffee Break |
| Ray MacDonald (UT Southwestern)
Pancreatic and salivary gland development |
| Discussion |
| Steve Konieczny (Purdue)
Maintenance of differentiated exocrine pancreas |
| Discussion |
| Gertraud Robinson (NIH, NIDDK)
Signaling pathways in mammary gland development |
| Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 6:00 pm | Free of all formal activities, Set-up for first Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Epithelial Cell Adhesion and Polarity |
| Discussion Leaders: Ray MacDonald (UT Southwestern) & Maria Kukuruzinska (Boston Univ.) |
| Steve Frisch (Burnham Institute)
Epithelial phenotype and anoikis |
| Discussion |
| Cara Gottardi (Sloan Kettering)
Epithelial cadherins |
| Discussion |
| Anne Muesch (Cornell Weill Med)
Epithelial polarity and trafficking |
| Discussion |
| David Bilder (UC Berkeley)
Epithelial polarity in Drosophila |
| Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Secretion and Regulation |
| Discussion Leaders: James Melvin (Rochester) & James Turner (NIH, NIDCR)
Introduction |
| Discussion |
| Haruo Kasai (NIPS, Okazaki, Japan)
Regulation of acinar exocytosis |
| Discussion |
| Edwin Chapman (Univ. of Wisconsin)
Calcium regulation of exocytosis |
| Discussion |
| 10:30 am - 11:00 am | Coffee Break |
| Anna Castle (Univ. of Virginia)
Pathways and regulation of secretion |
| Discussion |
| Anil Menon (U. of Cincinnati)
Regulation of fluid secretion |
| Discussion |
| 12:30 pm | Lunch |
| 4:30 pm - 6:00 pm | First Poster Session: |
| Mary Reyland (Univ. Colo), Masataka Murakami (NIPS, Okazaki, Japan), Lily Mirels (UC Berkeley), Tomomi Nemoto (NIPS, Okazaki, Japan), Eileen Watson (Univ. Washington), David Yule (Univ. Rochester), Co-Chairs and Poster Judges |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Transport and Diseases |
| Discussion Leaders: Anil Menon (Univ. of Cincinnati) & Trevor Shuttleworth (Rochester Univ)
Introduction |
| Peter Agre (Johns Hopkins)
Aquaporins in health and disease |
| Discussion |
| Kevin Kirk (Univ. of Alabama)
Molecular regulation of epithelial transporters |
| Discussion |
| David Cook (Univ. of Sydney, Australia)
Regulation and turnover of transporters |
| Discussion |
| John Scott (Oregon Health Sci Univ.)
AKAPS and scaffolding |
| Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Spatial Signaling |
| Discussion Leaders: Indu Ambudkar (NIH, NIDCR) & Frank Dowd (Creighton Univ)
Introduction |
| David Yule (Rochester)
Spatial calcium signals in exocrine acinar cells |
| Discussion |
| Shmuel Muallem (Univ. of Texas SW)
Organization of calcium signaling machinery |
| Discussion |
| 10:30 am - 11:00 am | Coffee Break |
| Mark von Zastrow (Univ. Cal. SF)
Trafficking in regulation of G-coupled receptors |
| Discussion |
| Sharon Milgram (Univ. of NC)
Organization and function of epithelial transporters |
| Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 5:30 pm | Free of all formal activities, Set-up for second Poster Session |
| 5:30 pm - 6:00 pm | Business Meeting, Election of next Vice-Chair |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Domains and Rafts in Signaling |
| Discussion Leaders: David Ann (U. of Sthrn. Cal.) & Steve Soltoff (Harvard Med) |
| Elina Ikonen (Natl Pub Hlth Inst, Finland)
Lipid rafts in epithelial cells |
| Discussion |
| Maurine Linder (Washington U.)
Membrane targeting of lipidated proteins |
| Discussion |
| Karl Matter (University College London, UK)
Junctional complex and differentiation |
| Discussion |
| Mikio Furuse (Kyoto University)
Junctional complexes, paracellular transport, polarity |
| Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Apoptosis and Autoimmune Disease in Epithelial Dysfunction |
| Discussion Leaders: Bruce Baum (NIH, NIDCR) & Antony Rosen (Johns Hopkins)
Introduction |
| Pierre Henkart, Nat. Cancer Inst, NIH
Death pathways induced by cytotoxic lymphocyte signaling |
| Discussion |
| Richard Kolesnick (Sloan Kettering)
Radiation, apoptosis and ceramide signaling |
| Discussion |
| 10:30 am - 11:00 am | Coffee Break |
| Mark Walport (Imperial College, UK)
C1q deficiency and impaired apoptotic cell clearance |
| Discussion |
| Donald Nicholson (Merck Frosst)
Pharmacologic inhibitors of caspase |
| Discussion |
| 12:30 pm | Lunch |
| 4:30 pm - 6:00 pm | Second Poster Session |
| Mary Reyland (Univ. Colo), Masataka Murakami (NIPS, Okazaki, Japan), Lily Mirels (UC Berkeley), Tomomi Nemoto (NIPS, Okazaki, Japan), Eileen Watson (Univ. Washington), David Yule (Univ. Rochester), Co-Chairs and Poster Judges |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | The Grand Finale |
| Announcement of Poster Winners |
| Discussion Leader: James Melvin (Rochester)
Introduction |
| Lawrence Tabak (NIH, NIDCR), Keynote Speaker
The Sweet Side of Salivary Function |
| Discussion |
| Tony Hunter (Salk Institute), Keynote Speaker
Signaling Networks and Proteomics |
| Discussion |
| "Post Mortem" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
