| Sunday |
| 2:00 p.m.-11:00 p.m. | Arrival & Registration |
| 6:00 p.m. | Dinner |
| 7:30 p.m. - 9:35 p.m. | Evening Session:
Opening Session |
| 7:30 p.m. - 7:45p.m. | David O. Quissell (Univ Colo Hlth Sci Ctr), Discussion Leader
Welcome & Introduction |
| 7:45 p.m. - 8:05 p.m. | Roland Jonsson (Broegelmann Res Lab, Univ of Bergen, Norway)
"Sjögren's Syndrome: Current Issues in Diagnosis, Autoantibodies and Pathogenesis"
|
| 8:05 p.m. - 8:15 p.m. | Discussion |
| 8:15 p.m. - 8:35 p.m. | Joel S. Greenberger (Dept. Radiat. Oncol., Univ Pittsburg Med Ctr)
"Combinational Cell Culture and Tissue Engineering" |
| 8:35 p.m. - 8:45 p.m. | Discussion |
| Keynote speaker: Anders Bennick (Univ. of Toronto, Canada)
"Saliva, the Raison d'être of Salivary Glands"
|
| 9:20 p.m. - 9:35 p.m. | Discussion |
| Monday |
| 7:30 a.m. - 8:30 a.m. | Breakfast |
| 9:00 a.m. - 12:30 p.m. | Morning Session:
Salt and Water Transport |
| 9:00 a.m. - 9:10 a.m. | James Turner (NIDCR), Discussion Leader
Introduction |
| 9:10 a.m. - 9:35 a.m | James Melvin (Univ of Rochester)
"AQP5 Water Channels and Salivary Gland Function" |
| 9:35 a.m. - 9:50 a.m. | Discussion |
| 9:50 a.m. - 10:30 a.m. | Photo & Coffee Break |
| 10:30 a.m. - 10:55 a.m. | David Cook (Univ of Sydney, Australia)
"The Analysis of Regulatory Systems in Transporting Epithelia" |
| 10:55 a.m. - 11:10 a.m. | Discussion |
| 11:10 a.m. - 11:35 a.m. | David C Dawson (Oregon Health Sciences Univ)
"The CFTR Chloride channel: A Dielectric Tunnel with a Charged Outer Vestibule" |
| 11:35 a.m. - 11:50 a.m. | Discussion |
| 11:50 a.m. - 12:15 a.m. | Ted B. Begenisich (Univ of Rochester)
"Maxi and Midi K Channels in Mouse Parotid Acinar Cells" |
| 12:15 a.m. - 12:30 a.m. | Discussion |
| 12:30 p.m. - 1:30 p.m. | Lunch |
| 1:30 p.m. - 6:00 p.m. | Free of all formal activities |
| 6:00 p.m. | Dinner |
| 7:30 p.m. - 9:35 p.m. | Evening Session:
Exocytosis - Vesicle Formation & Dynamics |
| 7:30 p.m. - 7:35 p.m. | J. David Castle (Univ of Virginia), Discussion Leader
Introduction |
| 7:35 p.m. - 7:55 p.m. | Maria Antonietta deMatteis (Santa Maria Imbaro, Italy)
"The Small GTPase ARF as a Regulator of Phosphoinositide Metabolism at the Golgi Complex: Molecular Mechanisms and Functional Implications" |
| 7:55 p.m.- 8:05 p.m. | Discussion |
| 8:05 p.m. - 8:25 p.m. | Marie France Bader (INSERM, Strasbourg, France)
"Regulated Secretion in Neuroendocrine Cells: An Essential role for an ARF-6-regulated phospholipase D in the Late Stages of Dense-core Granule Exocytosis" |
| 8:25 p.m. - 8:35 p.m. | Discussion |
| 8:35 p.m. - 8:55 p.m. | Anna Koffer (University College London, UK)
"Role of Actin and rho Proteins in Regulated Exocytosis from Mast Cells" |
| 8:55 p.m. - 9:05 p.m. | Discussion |
| 9:05 p.m. - 9:25 p.m. | Joe Angleton (University of Denver)
"Regulation of Compound Exocytosis in Isolated Pituitary Cells" |
| 9:25 p.m. - 9:35 p.m. | Discussion |
| Tuesday |
| 7:30 a.m. - 8:30 a.m. | Breakfast |
| 9:00 a.m. - 12:30 p.m. | Morning Session:
Glandular Development |
| 9:00 a.m. - 9:10 a.m. | Paul Denny (Univ of Southern California), Discussion Leader
Introduction |
| 9:10 a.m. - 9:35 a.m. | Deborah Andrew (Johns Hopkins Univ)
"Morphogenesis of the Drosophila Salivary Gland" |
| 9:35 a.m. - 9:50 a.m. | Discussion |
| 9:50 a.m. - 10:30 a.m. | Coffee Break |
| 10:30 a.m. - 10:55 a.m. | Ray MacDonald (Univ of Texas,Southwestern)
"Transcription Factors Controlling Pancreatic Gene Expression and Development" |
| 10:55 a.m. - 11:10 a.m. | Discussion |
| 11:10 a.m. - 11:35 a.m. | Tina Jaskoll (Univ of Southern California)
"FGF, BMP, Pax 6 and Pax 9 during Early Embryonic Submandibular Salivary Gland Morphogenesis: Protein Expression and Transgenic Analysis" |
| 11:35 a.m. - 11:50 a.m. | Discussion |
| 11:50 a.m. - 12:15 p.m. | Michael Melnick (Univ of Southern California)
"A probabilistic neural network analysis of the genomic and proteomic response of embryonic submandibular glands to NFkB inhibition" |
| 12:15 p.m. - 12:30 p.m. | Discussion |
| 12:30 p.m. - 1:30 p.m. | lunch |
| 1:30 p.m. - 4:00 p.m. | Free of all formal activities |
| 4:30 p.m. - 6:00 p.m. | Afternoon Session:
First Poster Session*** |
| . | J. David Castle (Univ of Virginia) & Masataka Murakami (National Institue for Physiological Sciences, Okazaki, Japan) Co-Chairs |
| 6:00 p.m. | Dinner |
| 7:30 p.m. - 9:35 p.m. | Evening Session:
Receptor & Intracellular Signaling Pathways |
| 7:30 p.m. - 7:35 p.m. | John Turner (Univ of Missouri Med Ctr), Discussion Leader
Introduction |
| 7:35 p.m. - 7:55 p.m. | Eileen Watson (Univ of Washington)
"G-protein Coupled Receptors and Mitogenic Signaling" |
| 7:55 p.m. - 8:05 p.m. | Discussion |
| 8:05 p.m. - 8:25 p.m. | Indu Ambudkar (NIDCR, Bethesda, MD)
"Molecular Mechanism of Calcium Influx: A Story of SOC and the Seven Trps" |
| 8:25 p.m. - 8:35 p.m. | Discussion |
| 8:35 p.m. - 8:55 p.m. | Mark Voigt (St. Louis Univ)
"Molecular and Functional Analysis of P2X Receptors" |
| 8:55 p.m. - 9:05 p.m. | Discussion |
| 9:05 p.m. - 9:25 p.m. | Carolyn Smith (Baylor College of Medicine)
"The Ups and Downs of Regulating Estrogen Receptor Transcriptional Activity" |
| 9:25 p.m. - 9:35 p.m. | Discussion |
| Wednesday |
| 7:30 a.m. - 8:30 a.m. | Breakfast |
| 9:00 a.m. - 12:30 a.m. | Morning Session:
Assembly of signaling complexes in cellular microdomains |
| 9:00 a.m. - 9:10 a.m. | Shmuel Muallem (Univ of Texas, Southwestern ), Discussion Leader
Introduction |
| 9:10 a.m. - 9:35 a.m. | Tullio Pozzan (Ferrara, Italy)
"Cellular microdomains in second messenger levels" |
| 9:35 a.m. - 9:50 a.m. | Discussion |
| 9:50 a.m. - 10:30 a.m. | Coffee Break |
| 10:30 a.m. - 10:55 a.m. | Daria Mochly-Rosen (Stanford Univ School of Medicine)
"Physiological Significance of PKC Localization"
|
| 10:55 a.m. - 11:10 a.m. | Discussion |
| 11:10 a.m. - 11:35 a.m. | Robert Arkowitz (Cambridge Univ., UK)
"Signaling Complexes and Establishment of Cell Polarity in Yeast" |
| 11:35 a.m. - 11:50 a.m. | Discussion |
| 11:50 a.m. - 12:15 a.m. | Henry Bourne (UCSF Medical Center)
"Chemotaxis and Polarized Signaling in Neutrophils" |
| 12:15 a.m. - 12:30 a.m. | Discussion |
| 12:30 p.m. - 1:30 p.m. | lunch |
| 1:30 p.m. - 6:00 p.m. | Free of all formal activites |
| 6:00 p.m. | Dinner |
| 7:00 p.m. - 7:30 p.m. | Business Meeting |
| 7:30 p.m. - 9:35 p.m. | Evening Session:
Cell Growth & Differentiation |
| 7:30 p.m. - 7:35 p.m. | Robert Sclafani (Univ of Colo Hlth Sci Ctr), Discussion Leader
Introduction |
| 7:35 p.m. - 7:55 p.m. | Kenneth Yamada (NIDCR, Bethesda,MD)
"Integrins, Signaling, and Cell Migration" |
| 7:55 p.m. - 8.05 p.m. | Discussion |
| 8:05 p.m. - 8:25 p.m. | Gerardo Ferbeyre (Cold Spring Harbor, NY)
"Senescence Induced by Oncogenic Ras"" |
| 8:25 p.m. - 8:35 p.m. | Discussion |
| 8:35 p.m. - 8:55 p.m. | David Olson (Genteric, Alameda, CA)
"Exocrine Organs as Platforms for Gene Therapy" |
| 8:55 p.m. - 9:05 p.m. | Discussion |
| 9:05 p.m. - 9:25 p.m. | Linda Samuelson (Univ of Michigan)
"Gastrointestinal Function in CCK and Gastrin Deficient Mice" |
| 9:25 p.m. - 9:35 p.m. | Discussion |
| Thursday |
| 7:30 a.m. - 8:30 a.m. | Breakfast |
| 9:00 a.m. - 12:30 p.m. | Morning Session:
Sjogren's Syndrome & Apoptosis |
| 9:00 a.m. - 9:10 a.m. | Phil Fox (Amarillo Biosci Inc, Cabin John, MD), Discussion Leader
Introduction |
| 9:10 a.m. - 9:35 a.m. | Antony Rosen (Johns Hopkins Med Ctr)
"Granzyme B Function in Target Cell Death" |
| 9:35 a.m. - 9:50 a.m. | Discussion |
| 9:50 a.m. - 10:30 a.m. | Coffee Break |
| 10:30 a.m. - 10:55 a.m. | Mary Reyland (Univ Colo Hlth Sci Ctr)
"Protein Kinase C alpha and delta are Reciprocal Regulators of Apoptosis in Salivary Acinar Cells" |
| 10:55 a.m. - 11:10 a.m. | Discussion |
| 11:10 a.m. - 11:35 a.m. | Michael Humphreys-Beher (Univ of Florida)
"Potential Regulation of Epithelial Cell Apoptosis by Th1 Cytokines in the NOD Mouse Model for Sjogren's Syndrome"
|
| 11:35 a.m. - 11:50 a.m. | Discussion |
| 11:50 a.m. - 12:15 a.m. | Steven Anderson (Univ Colo Hlth Sci Ctr)
"Activated AKT Delays Mammary Gland Involution and Suppresses Apoptosis"
|
| 12:15 a.m. - 12:30 a.m. | Discussion |
| 12:30 p.m. - 1:30 p.m. | Lunch |
| 1:30 p.m. - 4:00 p.m. | Free of All formal Activity |
| 4:00 p.m. - 6:00 p.m. | Afternoon Session:
Second Poster Session*** |
| | Gallya Gannot (Tel-Aviv Univ, Israel) & Mary Raynolds (Univ. Colo Hlth Sci Ctr) Co-Chairs |
6:00 p.m. | Dinner |
| 7:30 p.m. - 9:30 p.m. | Evening Session:
Functional Genomics |
| 7:30 p.m. - 7:35 p.m. | Brian O'Connell (Trinity College, Dublin, Ireland), Discussion Leader
Introduction |
| 7:35 p.m. - 7:55 p.m. | Matthew Hoffman (NIDCR, Bethesda, MD)
"Array Analysis of Salivary Gland Development: Where do we go from here?" |
| 7:55 p.m. - 8:05 p.m. | Discussion |
| 8:05 p.m. - 8:25 p.m. | David Ann (Univ of Southern California)
"Cell Signaling in Salivary Adaptive Responses" |
| 8:25 p.m. - 8:35 p.m. | Discussion |
| 8:35 p.m. - 8:55 p.m. | Carol Basbaum (UCSF Medical Ctr)
"Pathogen Effects on Intracellular Signaling and Mucin Production in the Host" |
| 8:55 p.m. - 9:05 p.m. | Discussion |
| Friday |
| 7:30 a.m. - 8:30 a.m. | Breakfast |
| 9:00 a.m. | Departure |
