Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Epidemiology, Vaccines, and Treatments
3:15 pm - 3:25 pm
"Final Efficacy Results of a Typhoid Conjugate Vaccine (TCV) Trial Among Malawian Children"
3:25 pm - 3:30 pm
Discussion
3:30 pm - 3:40 pm
"Antibodies Induced by GMMA-Based Vaccine Candidates Against Invasive Nontyphoidal Salmonellosis are Able to Kill a Panel of Epidemiologically Relevant Salmonella Strains"
3:40 pm - 3:45 pm
Discussion
3:45 pm - 3:55 pm
"Sero-Epidemiology in Africa of Invasive Non-Typhoidal Salmonellosis (SAiNTS Study); Study Aims, Design and Early Findings"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Virulence, Metabolism, and Physiology of Salmonella
5:30 pm - 5:40 pm
"The Salmonella Typhimurium Effector SifA Controls Bacterial Dormancy in Epithelial Cells"
5:40 pm - 5:45 pm
Discussion
5:45 pm - 5:55 pm
"Ingestion of Sugar Substitutes Promotes Gut Colonization and Virulence in Salmonella Typhimurium"
5:55 pm - 6:00 pm
Discussion
6:00 pm - 6:10 pm
"The role of Salmonella Protease PgtE in Evading Host Immune Response"
6:10 pm - 6:15 pm
Discussion
6:15 pm - 6:25 pm
"Salmonella Histidine Metabolism Regulates SPI-2-Dependent Late Macrophage Apoptosis"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"Succinate Metabolism in the Host and the Pathogen During Salmonella Typhimurium Infection"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
"Salmonella Minimal SPI2 Effector Networks During Pathogenesis"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
"Overcoming the challenges of In Vivo Transcriptomics of Salmonella Typhimurium During Infection"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Integrity of the Salmonella -Containing Vacuole as Decisive Event in Host Cell Exit of Salmonella Enterica"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
The Impact of Host Immunity and the Microbiota
9:00 am - 9:10 am
"Diet-Driven Distinct Amino Acid Profile Drives Susceptibility to S . Tm Gastroenteritis"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"The Role of IL-1ß in Protection from Salmonella Infection"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Sulfur Metabolism Enables S . Typhimurium to Compete More Successfully with Close Relatives During Gut Inflammation"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Investigating Host Responses to Salmonella Typhi in Acute Typhoid Fever"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Multi-Omics Exposes Persistent Bacteria and Infers New Metabolism in the Inflamed Salmonella -Included Gut"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Cytotoxic CD4+ T Cells and IFN-? Orchestrate the Induction of Apoptosis During Salmonella Typhimurium Infection"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Detecting and Monitoring Salmonella Infection and Chronic Carriage in Living Mice Using Bioluminescent in Vivo Imaging"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
"Salmonella Typhimurium -Induced Malabsorption Supports Initial Expansion in the Large Intestine"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Discussion Panel: Mentoring and Career Advice
1:30 pm - 2:30 pm
Panel Discussion
Mentoring and Career Advice
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes