SESSION I: Sunday (A. M.), August 13, 1995
INTERACTIONS BETWEEN GROWTH FACTOR AND G PROTEIN-MEDIATED SIGNAL
TRANSDUCTION PATHWAYS
Chair:
Dr. Beverly Errede (University of North Carolina), "MAP-kinase activation pathways in yeast"
Dr. Tom Sturgill (Vice Chairman of the Conference), "Regulation of MAP kinase"
Dr. Gary Johnson (National Jewish Center of Immunology, Denver), "Tyrosine kinase and G protein regulation
of sequential protein phosphorylation pathways"
Dr. Joseph Schlessinger (New York University School of Medicine, N.Y.), "Cellular signalling by tyrosine
phosphorylation"
SESSION II: Sunday (P. M.), August 13, 1995
REGULATION OF G PROTEIN-COUPLED RECEPTOR SIGNALLING
Chair:
Dr. Shaun Coughlin (UCSF Department of Medicine, San Francisco), "Molecular mechanisms of thrombin
signalling"
Dr. Randall Reed (Johns Hopkins University, Baltimore), "Regulation of olfactory signalling"
Dr. Jeff Benovic (Thomas Jefferson University, Philadelphia), "Role of phosphorylation in G protein-coupled
receptor regulation"
SESSION III: Monday (A. M.), August 14, 1995
STRUCTURE AND FUNCTION OF HETEROTRIMERIC G PROTEINS, AND THEIR ROLES IN
SIGNAL TRANSDUCTION PATHWAYS
Chair:
Dr. Eva Neer (Harvard Medical School, Boston), "The G subunit and its relatives"
Dr. Joe Noel (Salk Institute, San Diego), "Crystallographic studies of transducin structures"
Dr. David Stone (University of Illinois at Chicago, Chicago), "Gà-mediated adaptation to phenomone-a novel
signalling pathway in yeast"
Dr. Steven Sprang (University of Texas Southwestern Medical Center), "Catalysis and regulation of Già"
Dr. Mel Simon (California Institute of Technology, Los Angeles), "Novel signal transducers and new ways of
looking at them"
SESSION IV: Monday (P. M.), August 14, 1995
ROLE OF POSTTRANSLATIONAL MODIFICATIONS IN G PROTEIN-MEDIATED SIGNALLING
PATHWAYS
Chair:
Dr. Maurine Linder (Washington University, Saint Louis), "G protein palmitoyltransferase"
Dr. Pat Casey (Duke University, Durham NC), "Protein prenylation: Mechanisms and consequences"
Dr. Teresa Jones (National Institutes of Health, Bethesda MD), "Lipid modifications of G protein à subunits"
SESSION V: Tuesday (A. M.), August 15, 1995
STRUCTURE, FUNCTION AND REGULATION OF ENZYMES WHICH CONTROL SECOND
MESSENGERS
Chair:
Dr. Ravi Iyengar (Mt. Sinai Medical Center, New York), "Signal processing by adenylyl cyclase isoforms"
Dr. Sue Goo Rhee (National Institutes of Health, Bethesda MD), "Regulation of phospholipase C isozymes"
Dr. Weijen Tang (University of Chicago, Chicago, IL), "Construction of a soluble, Gsà and forskolin-activated
adenylyl cyclase"
Dr. Heidi Hamm (University of Illinois at Chicago, Chicago), "Regulation of cGMP phosphodiesterase by
transducin"
SESSION VI: Tuesday (P. M.), August 15, 1995
PATHWAYS OF SIGNAL TRANSDUCTION MEDIATED BY G PROTEIN BETA GAMMA SUBUNITS
Chair:
Dr. Narasimhan Gautam (Washington University, Saint Louis), "A role for the G protein By complex in
regulation of signalling specificity"
Dr. Lou Luttrell (Duke University, Durham NC), "By interaction with pleckstrin homology domains in some
novel pathways"
Dr. Janet Robishaw (Weis Ctr. Res., Geisinger Clinic, Danville PD), "Role of y subunit in conferring selectivity
of G protein àBy assembly"
SESSION VII: Wednesday (A. M.), August 16, 1995
SIGNALLING PATHWAYS MEDIATED BY SMALL G PROTEINS
Chair:
Dr. Gary Bokoch (Scripps Research Institute of Immunology, La Jolla), "Regulation of cell function by Rac/Rho
GTPases"
Dr. Alfred Wittinghofer (Max Planck Institt fr Molekulare Physiologie, Dortmund), "Structural and functional
studies on raf-rap and raf-ras interactions"
Dr. Lewis Cantley (Harvard Med Sch, Boston), "Structural basis for protein kinase specificity"
Rick Cerione (Cornell University, New York), Biochemical regulation of a ras-like ptotein that influences cell
polarity and cytokinesis"
SESSION VIII: Wednesday (P. M.), August 16, 1995
KEYNOTE LECTURE
Speaker:
Dr. Henry Bourne (UCSF Department of Pharmacology, San Francisco), "Some stories about G proteins"
SESSION IX: Thursday (A. M.), August 17, 1995
EMERGING PATHWAYS OF SIGNAL TRANSDUCTION
Chair:
Dr. John Spudich (University of Texas Medical School, Houston), "Signalling mechanism of the seven-helix
receptor sensory rhodopsin-I"
Dr. Suzanna Klumpp (California Institute of Technology, Los Angeles), "Histidine phosphorylation and
dephosphorylation"
Dr. Hon Cheung Lee (University of Minnesota, Minneapolis), "Calcium signalling by cyclic ADP-ribose"
Dr. Richard Kolesnick (Sloan-Kettering Cancer Center, New York), "The role of protein phosphorylation in
signal transduction through the sphingomyelin pathway"
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