Session I: Sunday evening, June 9, 1996
Signal initiation by tyrosine protein kinases and G-protein linked receptors
- Session Chair: Dr. Morris White (Joslin Diabetes Center, Boston, MA) "The role of IRS-proteins in insulin and cytokine action"
- Dr. Christin Carter-Su (University of Michigan Medical School, Ann Arbor, MI) "The role of JAK2 tyrosine kinase in signalling by growth hormone"
G-protein Conference
- Session Chair: Dr. Patrick Casey (Duke University Medical Center, Durham, NC) "Mechanisms of G Protein Targeting and Activation"
- Dr. Andrew Larner (FDA, Bethesda, MD) "Regulation of cytokine stimulated early response genes by protein phosphorylation"
Session II: Monday (a.m.), June 10, 1996
Lipid second messengers
- Session Chair: Dr. John Exton (Vanderbilt University, Nashville, TN) "G protein control of phospholipases"
- Dr. Yusuf Hannun (Duke University, Durham, NC) "Ceramide: an intracellular stress signal"
Session III: Monday (p.m.), June 10, 1996
Regulation of protein kinases
- Session Chair: Dr. Bruce Kemp (St. Vincent's Institute of Medical Research, Melbourne, Australia) "Architecture of protein kinase regulation"
- Dr. Susan Taylor (University of California-San Diego, La Jolla, CA) "Structural insights into catalysis and inhibition of cAMP-dependent protein kinase"
- Dr. Melanie Cobb (University of Texas Southwestern Medical Center, Dallas, TX) "Regulation of MAP kinase and parallel cascades"
- Dr. Angus Nairn (Rockefeller University, New York, NY) "Structure and function of Ca2/calmodulin-dependent protein kinases"
Session IV: Tuesday (a.m.), June 11, 1996
Kinase cascades
- Session Chair: Dr. Gary Johnson ( Nat'l Jewish Center for Immunology & Respiratory Medicine, Denver, CO) "Multiple protein kinase cascades regulate proliferation and apoptosis"
- Dr. George Thomas (Friedrich Miescher Institut, Basel, Switzerland) The p70s6k/p85s6k signalling pathway and its effect on translation"
- Professor Philip Cohen (University of Dundee, UK) "Dissection of protein kinase cascades which mediate cellular responses to growth factors, cytokines and stress"
- Dr. John Lawrence (Washington University School of Medicine, St. Louis, MO) "PHAS regulation of cellular function"
Session V: Tuesday (p.m.), June 11, 1996
cAMP Metabolism and the Cell Cycle
- Session Chair: Dr. Jim Maller (University of Colorado, Denver, CO)
- Dr. Joe Beavo (University of Washington, Seattle, WA) "Cyclic nucleotide phosphodiesterases and the cell cycle"
- Dr. Charles Rubin (Albert Einstein College of Medicine, Bronx, NY) "Control and consequences of the intracellular anchoring of PKA"
- Dr. Maureen McLeod (State University of NYHSC, Brooklyn, NY) "Regulation of the transition between mitosis and meiosis by ranl+ kinase and cAMP-dependent protein kinase"
- Dr. Ned Lamb (Centre Recherches Biochimistrie, Montpellier, France) "Interphase-mitotic transition: implications for cAMP-dependent pathways"
Session VI: Wednesday (a.m.), June 12, 1996
Protein Phosphatases
- Session Chair: Dr. Anna DePaoli-Roach (Indiana University School of Medicine, Indianapolis, IN) "Serine/threonine protein phosphatases in MAP kinase signal transduction pathways"
- Dr. Jim Maller (University of Colorado, Denver, CO) "Regulation of CDC25 in the cell cycle"
- Dr. Marc Mumby (University of Texas Southwestern Medical Center, Dallas, TX) "Tumor antigens define roles for PP2A in signal transduction and regulation of the cytoskeleton"
- Dr. Nick Tonks (Cold Spring Harbor, NY) "Structure, regulation and function of protein tyrosine phosphatases"
Session VII: Wednesday (p.m.), June 12, 1996
Metabolic Actions of Insulin
- Session Chair: Dr. Lee Witters (Dartmouth Medical School, Hanover, NH) "Distal targets of insulin action"
- Dr. Peter Roach (Indiana University School of Medicine, Indianapolis, IN) "Multiple mechanisms for the control of glycogen synthase in mammals and yeast"
- Dr. Morey Birnbaum (Harvard Medical School, Boston, MA) "The regulation of glucose transport by insulin"
- Dr. Maria Alexander-Bridges (Massachusetts General Hospital, Boston, MA) "Insulin signalling to genes that control nutrient availability"
Session VIII: Thursday (a.m.), June 13, 1996
Regulation by protein phosphorylation and dephosphorylation
- Session Chair: Dr. Tom Sturgill (University of Virginia, Charlottesville, VA) "Raf activation and inactivation"
- Dr. David Brautigan (University of Virginia, Charlottesville, VA) "Regulation of protein phosphatase 2A"
- Dr. Perry Blackshear (Duke University, Durham, NC) "Structure-function studies of the MARCKS protein"
Session IX: Thursday (p.m.), June 13, 1996
Keynote Session
- Dr. Joseph Avruch (Massachusetts General Hospital, Charlestown, MA) "Edging toward insulin action"
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