| Sunday evening, June 6th |
Session #1 |
| Cdk function and checkpoint mechanisms |
- Emma Lees, DNAX Research Institute of Molecular and Cellular Biology, Palo Alto, CA
"Searching for substrates of cyclin-dependent protein kinases"
- Brenda Andrews, University of Toronto, Toronto, Canada, Session Chair
"Cyclin-dependent kinase specificity and function in budding yeast"
- Paul Russell, Department of Molecular Biology, Scripps Research Institute, La Jolla, CA
"DNA replication and DNA damage checkpoints in fission yeast"
- David F. Stern, Yale University School of Medicine, New Haven, CT
"Roles of Rad53 protein kinase and its forkhead-associated (FHA) domain in DNA checkpoint controls"
| Monday morning, June 7th |
Session #2 |
| Roles of adenosine and its derivatives in cell signaling |
- R. Alan North, University of Sheffield, Sheffield, U.K.
"ATP-gated ion channels"
- Joel Linden, University of Virginia, Charlottesville, VA
"Signaling via adenosine receptors"
- Bruce Kemp, Saint Vincent's Institute, Victoria, Australia
"Dealing with energy demand: 5'-AMP-activated protein kinase"
- G. Stanley McKnight, University of Washington, Seattle, WA
, Session Chair
"Physiological role of cyclic AMP-dependent protein kinase in body fat regulation"
| Monday evening, June 7th |
Session #3 |
| Modulators of heterotrimeric G proteins & G-protein-coupled receptors |
- Eva Neer, Brigham and Women's Hospitals & Harvard Medical School, Boston, MA, Session Chair
"G Proteins and their effectors"
- Rachelle Gaudet , Harvard University, Cambridge, MA
"Regulation of a regulator: Structure, function, and phosphorylation of phosducin"
- Henrik Dohlman, Yale University School of Medicine, New Haven, CT
"Regulation of G protein signaling in yeast"
- Alan Wise, GlaxoWellcome Medicines Research Centre, Hertfordshire, UK
"Expression and pharmacology of 7-TM receptors can be dependent on accessory proteins"
| Tuesday morning, June 8th |
Session #4 |
| Regulation of apoptosis and cell survival |
- Vishva Dixit, Genentech, Inc., South San Francisco, CA, Session Chair
"Identification of components of the cell death pathway"
- Nancy A. Thornberry, Merck Research Laboratories, Rahway, NJ
"Caspases and their roles in apoptosis"
- Andreas Strasser, Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
"Apoptosis signaling pathways in mammalian cells"
- Michael O. Hengartner, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
"Signal transduction during cell death in the nematode, C. elegans"
| Tuesday evening, June 8th |
Session #5 |
| Lipid-activated signaling and related pathways |
- Michael N. Hall, University of Basel, Basel, Switzerland
"TOR signaling in yeast: Temporal and spatial control of cell growth"
- John Blenis, Harvard Medical School, Boston, MA, Session Chair
"Proliferative and survival signals mediated by the ERK/RSK and S6K1/S6K2 protein kinases"
- Yukiko Gotoh, University of Tokyo, Tokyo, Japan
"Signaling pathways for cell survival"
- Jack Dixon, University of Michigan, Ann Arbor, MI
"PTEN: a tumor suppressor that functions as a phospholipid phosphatase"
| Wednesday morning, June 9th |
Session #6 |
| Integrin-mediated signaling |
- Joan Brugge, Harvard Medical School, Boston, MA, Session Chair
"Regulation of integrin signaling through the Rho family guanine nucleotide exchange factor, Vav"
- Martin A. Schwartz, Scripps Research Institute, La Jolla, CA
"MAP kinase and Rho family GTPases in integrin signaling"
- Kristiina Vuori, The Burnham Institute, La Jolla, CA
"The Cas-Crk signaling complex in integrin signal transduction"
- Arnoud Sonnenberg, Netherlands Cancer Institute, Amsterdam, Netherlands
"Roles of the integrin alpha6-beta4 in hemidesmosome assembly"
| Wednesday evening, June 9th |
Session #7 |
| Signaling pathways mediated by small G proteins |
- Gideon Bollag, Onyx Pharmaceuticals, Inc., Richmond, CA
"Linking GTPases via exchange factors"
- Louis Lim (or Ed Manser), University of London, London, U.K.
"Modular activities of kinase effectors and their role in specifying Rho GTPase actions"
- Linda Van Aelst, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
"Targets of Ras and Rac: functions and signal transduction"
- Kozo Kaibuchi, Nara Institute of Science and Technology, Nara, Japan, Session Chair
"Structure, function, regulation, and action of Rho-activated protein kinases"
| Thursday morning, June 10th |
Session #8 |
| Signaling via growth factor receptors |
- Joseph Schlessinger, New York University School of Medicine, New York, NY, Session Chair
"Cellular signaling by tyrosine phosphorylation"
- Tony Hunter, The Salk Institute for Biological Studies, La Jolla, CA
"Signaling by receptor protein-tyrosine kinases and phosphatases"
- George Yancopoulos, Regeneron Pharmaceuticals, Inc., Tarrytown, NY
"Helping orphan receptors find their growth factor partners: Tales of neurons, muscle, bone and the vasculature"
- Dafna Bar-Sagi, State University of New York at Stony Brook, Stony Brook, NY
"Ras signaling and growth control"
| Thursday evening, June 10th |
Session #9 |
| MAPK-based signaling cascades |
- Natalie Ahn, University of Colorado, Boulder, CO
"Examining the MKK/ERK pathway by proteomics"
- James E. Ferrell, Stanford University School of Medicine, Stanford, CA
"MAPK and mitosis: some arresting mechanisms"
- Lee Bardwell, University of California, Irvine, Irvine, CA
"New mechanisms of specificity in MAP kinase signaling"
- Melanie Cobb, University of Texas Southwestern Medical Center, Dallas, TX, Session Chair
"Structure, regulation, and function of MAP kinase pathways"
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