PAS domains
Chair: Jim Hoch

• Getzoff, E. "Envisioning a protein photocycle at atomic resolution: Spanning time scales from photon physics to biology."
• Bauer, C. "Genetic and biochemical characterization of a novel PYP-phytochrome hybrid"
• Gilles-Gonzalez, M. "Evidence for an O2-sensing subgroup of PAS domains that are not limited to histidine kinase or Rhizobial regulation"
• Taylor, B. "The role of the Aer PAS domain in sensing redox potential and energy"
• Briggs, W. "Flavin-binding domains in the plant photoreceptor phototropin"

Receptors
Chair: Ikuro Kawagishi

• Manson, M. "Testing a computer-generated model for MBP-Tar docking by intermolecular crosslinking between introduced cysteine residues."
• SungHo Kim "Crystal structure of the cytoplasmic domain of Tsr and its functional implications"
• Falke, J. "The Aspartate Receptor: Transmembrane Signal and the Cytoplasmic Domain"
• Parkinson, S.J. "CheA Kinase Control by Receptor Signaling Complexes"

11:00-11:30: Break and Group Photo

• Hazelbauer, G. "Transmembrane Conformational Signaling and Adaptation"
• Weis, R. "Covalent Modification Regulates Ligand Binding to the Serine Receptor Complexes of Escherichia coli"

Two-component signalling
Chair: Ann Stock

• Wilkinson, A. "Phosphorylated aspartate signalling in the sporulation response regulator, Spo0A"
• Samama, J.P. "Phosphorylation-induced conformational change in the receiver domain of FixJ"
• Mini-talk Kahn, D. "The role of FixJ Phe101 in signal transduction"
• Kerns, D. "Structure and dynamics of a signaling protein "in action" - the phosphorylated receiver domain of NtrC"
• Westbrook, E. "Constitutively Active CheY mutant bound to a FliM peptide"
• Mini-talk Yan, D. "Aspartyl beryllofluoride -- an aspartyl phosphate analog in responseregulators
• Mini-talk Ho Cho "The NMR Structure of BeF3 Activated CheY"

Signalling Pathways
Chair: Mel Simon

• Koshland, D.E. "The Aspartate Receptor and Transmembrane Signaling."
• Stock, J. "Receptor scaffold architecture and the regulation of CheA"
• Bilwes, A.. 'Nucleotide binding by the histidine kinase CheA"
• Dahlquist, F.W. "Structure and function of CheW"

Break

• Inouye, M. "Structure and function of EnvZ, an osmosensory histidine kinase".
• Mini-talk Hoch, J.A. (10 minutes) "Understanding the code for molecular recognition between response regulators and phosphotransferase domains"
• Mini-talk Hubbard, J. (10 minutes) "Ligand interactions with protein components of bacterial two-component signalling systems probed by NMR spectroscopy"

Motor Structure
Chair: David DeRosier

• Macnab, R.M. "The flagellar export pathway--components, substrates and interactions"
• Aizawa, S. "Type III flagellar export and virulence factor secretion systems in S. typhimurium"
• Khan, S. "Overproduced S. typhimurium flagellar motor switch complexes".
• Blair, D. "Biochemical and structural studies of flagellar motor components: implications for the mechanism of rotation."

Mini Talks (10 minutes)

• Berg, H.C. "Flagellar motor mechanics"
• Eisenbach, M. "Hysteresis of the flagellar switch: forward is not equivalent to reverse"

G-Protein signalling
Chair: Jeff Segall

• P. Devreotes Dictyostelium signaling "Gradient Sensing in Eukaryotic Cells""
• R. Firtel "Signaling mechanisms controlling cell polarization and chemotaxis"
• G. Gerisch "The actin skeleton and cell organelles in chemotaxis "
• R. Arkowitz "G-proteins mediate changes in cell shape by stabilizing axis of polarity"
• G. Bokoch "Cytoskeletal signaling by human neutrophil chemoattractant receptors via Rho GTPases"

Mini Talks

• J. Rifkin - 5, "Folate receptors of vegetative Dictyostelium discoideum amoebae: distribution and trafficking "
• A. Kimmel - 10, "Kinase signaling dowmstream of 7-transmembrane chemoattractant receptors"

Signaling Diversity Workshop

• Mandy Ward ("Modifications to the chemotaxis and signal transduction paradigms in non-enteric bacteria (the STRANGE bugs)")

Signalling diversity
Chair: David Zusman

• Kirby, J. "Multiple chemoreceptor/transducers in Myxococcus xanthus"
• Armitage, J. "The role of multiple chemosensory proteins in the behavior of Rhodobacter spaeroides"

Maxi-Talks

• Ordal, G. "The Roles of Methylation, CheY-P, and CheV during chemotactic adaptation in Bacillus subtilis"
• Oesterhelt, D. "Soluble and membrane bound chemoreceptors in halophilic archaea"
• Spudich, John "Archaeal sensory rhodopsin/transducer; interaction and phototaxis signalling "
• Maddock, J. "The Caulobacter GTPase CgtA, displays unusual guanine nucleotide binding and exchange properties"

Eukaryotic signalling
Chair: Ann West

• West, A. "YPD1-mediated histidine to aspartate phosphoryl transfer in S. cerevisiae"
• Fassler, J. "A branched phosphorelay pathway that coordinates osmotic and oxidative stress responses in S. cerevisiae"
• Borkovich, K. "NOP-1 from Neurospora crassa represents a new family of eukaryotic opsins"
• Schuster, S. "Development and osmotic stress regulation share a common pathway: Two-component and cAMP signaling in Dictyostelium"
• Loomis, W. "Signaling through histidine kinases and response regulators in Dictyostelium"
• Chang, C. "The ethylene hormone-response pathway: Two-component signaling in Arabidopsis".

Signaling Diversity Workshop

• Shahid Khan ("Amplification in Sensory Transduction Circuits")

Quorum Sensing
Chair: Peter Greenberg

• Greenberg, P. "The language of Gram-negative bacteria"
• Farrand, S. "Enviromental cues and quorum-sensing in Agrobacterium"
• Gomer, R. "Cell number counting in Dictyostelium"
• Morrison, D.A. "Quorum-sensing for genetic exchange in the streptococci"

Mini-talks (10 minutes)

• Pesci, E. "Quinolone signaling by Pseudomonas aeruginosa"
• Rather, P. "Cell-to-cell signaling in E. coli".