| SUNDAY |
| 4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:45 pm) |
| 6:00 pm | Dinner |
| 7:30 pm - 7:35 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:35 pm - 9:30 pm | DIVERSITY IN MICROBIAL CHEMOTAXIS |
| Discussion Leader: Chris Rao (University of Illinois - Urbana) |
| 7:35 pm - 7:45 pm | Discussion Leader's remarks |
| 7:45 pm - 8:10 pm | Igor Zhulin (University of Tennessee - Oak Ridge National Laboratory)
"What we did not know about E. coli chemotaxis"
|
| 8:10 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:45 pm | Mike Manson (Texas A&M University)
"Chemotaxis to the quorum signal: autoinducer 2"
|
| 8:45 pm - 8:55 pm | Discussion |
| 8:55 pm - 9:20 pm | Karen Ottemann (University of California Santa Cruz)
"Chemotaxis as a mechanism for delivery of virulence factors"
|
| 9:20 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | SMALL MOLECULE SIGNALING |
| Discussion Leader: Liz Sockett (University of Nottingham) |
| 9:00 am - 9:10 am | Discussion Leader's remarks |
| 9:10 am - 9:35 am | Angelika Grundling (Imperial College, London)
"C-di-AMP synthesis in Staphylococcus aureus"
|
| 9:35 am - 9:40 am | Discussion
|
| 9:40 am - 10:05 am | Urs Jenal (University of Basel)
"Cyclic di-GMP signaling in Caulobacter crescentus"
|
| 10:05 am - 10:10 am | Discussion |
| 10:10 am | Group Photo / Coffee Break |
| 10:35 am - 11:00 am | Chris Waters (Michigan State University)
"Elucidating cyclic di-GMP signaling in Vibrio cholerae"
|
| 11:00 am - 11:05 am | Discussion |
| 11:05 am - 11:30 am | Andrew Lovering (University of Birmingham)
"Structural studies of an unconventional HD-GYP Protein from Bdellovibrio bacteriovorus"
|
| 11:30 am - 11:35 am | Discussion |
| 11:35 am - 12:00 pm | Gladys Alexandre (University of Tennessee)
"C-di-GMP sensing by a chemotaxis-like pathway that regulates clumping in Azospirillum brasilense"
|
| 12:00 pm - 12:05 pm | Discussion |
| 12:05 pm - 12:20 pm | Beiyan Nan (University of California, Berkeley)
"FrzN, a modulator that links cyclic di-GMP metabolism to Frz signaling in Myxococcus xanthus"
|
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 1 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | RECEPTOR SIGNALING AND ARCHITECTURE DESIGN |
| Discussion Leader: Sandy Parkinson (University of Utah) |
| 7:30 pm - 7:40 pm | Discussion Leader's remarks |
| 7:40 pm - 8:00 pm | Ariane Briegel (California Institute of Technology)
"Electron cryotomography of bacterial chemoreceptor arrays"
|
| 8:00 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:25 pm | Gerald Hazelbauer (University of Missouri)
"The core unit of chemotaxis signaling complexes"
|
| 8:25 pm - 8:35 pm | Discussion |
| 8:35 pm - 8:55 pm | Joseph Falke (University of Colorado)
"Mechanisms of on-off switching and ultrastability in the chemosensory signaling array"
|
| 8:55 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Joachim Schultz (University of Tuebingen)
"Tsr-serine transmembrane signaling: characterization of a signal processing module"
|
| 9:20 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | PHOSPHORYLATION AND ACETYLATION IN SIGNAL TRANSDUCTION |
| Discussion Leader: Ann West (University of Oklahoma) |
| 9:00 am - 9:10 am | Discussion Leader's remarks |
| 9:10 am - 9:20 am | Mini-talk: Takashi Sagawa (Tohoku University)
"Measurement of single cellular response time to photoreleased serine from caged compound" |
| 9:20 am - 9:25 am | Discussion |
| 9:25 am - 9:35 am | Mini-talk: Kuang He (Indiana University)
"A histidine kinase CheS3 regulates cyst formation in Rhodospirillum centenum by sensing intracellular energy levels"
|
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 10:05 am | Sean Crosson (University of Chicago)
"Structural mechanism of stress regulation by PhyR, a novel response regulator that is a receiver domain - extracytoplasmic sigma factor-like domain"
|
| 10:05 am - 10:10 am | Discussion |
| 10:10 am | Coffee Break |
| 10:35 am - 11:55 am | Stephen Porter (University of Exeter)
"Mechanisms of communication between histidine protein kinases in Pseudomonas aeruginosa"
|
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 11:25 am | Michael Eisenbach (Weizmann Institute of Science)
"N-acetylation of CheY: a novel dual regulation mechanism of bacterial chemotaxis"
|
| 11:25 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | Alan Wolfe (Loyola University)
"Protein acetylation impacts signal transduction and gene expression"
|
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:25 pm | Kathleen Ryan (University of California Berkeley)
"Cell wall regulation in Caulobacter by a tyrosine phosphatase"
|
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 1 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | MOTILITY |
| Discussion leader: Kelly Hughes (University of Utah) |
| 7:30 pm - 7:40 pm | Discussion Leader's remarks |
| 7:40 pm - 8:00 pm | Katsumi Imada (Osaka University)
"Assembly mechanism of the stator unit of the sodium driven motor"
|
| 8:00 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:30 pm | Ken Jarrell (Queen's University, Canada)
"The unique version of flagella found in Archaea" |
| 8:30 pm - 8:35 pm | Discussion |
| 8:35 pm - 8:55 pm | Makoto Miyata (Osaka City University)
"Gliding mechanism suggested from isolated machinery of Mycoplasma mobi"
|
| 8:55 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:25 pm | Gerard Wong (University of California Los Angeles)
"Slingshots, earthquakes, and capitalist economies: three vignettes on the relation between type IV pili and EPS"
|
| 9:25 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | FLAGELLA STRUCTURE AND FUNCTION |
| Discussion Leader: Shin-Ichi Aizawa (Prefectural University of Hiroshima) |
| 9:00 am - 9:10 am | Discussion Leader's remarks |
| 9:10 am - 9:35 am | Lawrence Lee (The Victor Chang Cardiac Research Institute, Australia)
"Structure of the torque ring of the flagellar motor and the molecular basis for rotational switching"
|
| 9:35 am - 9:45 am | Discussion |
| 9:45 am - 10:10 am | Torhu Minamino (Osaka University)
"Switching mechanism of flagellar motor rotation"
|
| 10:10 am - 10:20 am | Discussion |
| 10:20 am | Coffee Break |
| 10:45 am - 11:10 am | Rick Dahlquist (UC Santa Barbara)
"Crystal structure of a large piece of FliG bound to FliM"
|
| 11:10 am - 11:20 am | Discussion |
| 11:20 am - 11:45 am | David Blair (University of Utah)
"Molecular mechanisms of the flagellar direction switch in E. coli"
|
| 11:45 am - 11:55 am | Discussion |
| 11:55 am - 12:20 pm | Jun Liu (University of Texas at Houston)
"The 3-D structure of the intact flagellar motor in living bacteria"
|
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 2 |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
| 7:30 pm - 9:30 pm | SINGLE CELL STUDIES |
| Discussion Leader: Yuhai Tu (IBM Watson Research Center) |
| 7:30 pm - 7:40 pm | Discussion Leader's remarks |
| 7:40 pm - 8:05 pm | Thierry Emonet (Yale University)
"Bacterial chemotaxis from the single cell perspective"
|
| 8:05 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:40 pm | Roman Stocker (Massachusetts Institute of Technology)
"High-performance chemotaxis and aerotaxis of marine bacteria"
|
| 8:40 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:15 pm | Ned Wingreen (Princeton University)
"Why so many feedbacks in Vibrio harveyi quorum sensing?"
|
| 9:15 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | RESPONSES TO THE PHYSICAL ENVIRONMENT |
| Discussion Leader: Kirsten Jung (Ludwig-Maximilians University) |
| 9:00 am - 9:10 am | Discussion Leader's remarks |
| 9:10 am - 9:35 am | Zemar Gitai (Princeton University)
"How P. aeruginosa senses and responds to its mechanical environment"
|
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 10:05 am | Victor Sourjik (University of Heidelberg)
"Thermal robustness and thermal sensing in E. coli chemotaxis"
|
| 10:05 am - 10:10 am | Discussion |
| 10:10 am | Coffee Break |
| 10:35 am - 11:00 am | Linda Kenney (University of Illinois - Chicago)
"The mechanism of osmosensing by EnvZ"
|
| 11:00 am - 11:05 am | Discussion |
| 11:05 am - 11:30 am | Zhaomin Yang (Virginia Tech)
"The type IV pilus assembly ATPase functions in a signal transduction pathway in Myxococcus xanthus"
|
| 11:30 am - 11:35 am | Discussion |
| 11:35 am - 12:00 pm | John Kirby (University of Iowa)
"Two component system - chemosensory system interaction in Myxococcus xanthus"
|
| 12:00 pm - 12:05 pm | Discussion |
| 12:05 pm - 12:20 pm | Doug Weibel (University of Wisconsin)
"Measuring cell mechanics by watching cells push on their environment"
|
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 2 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | SPATIAL ORGANIZATION IN CELLS AND POLARITY |
| Discussion Leader: Janine Maddock (University of Michigan) |
| 7:30 pm - 7:40 pm | Discussion Leader's remarks |
| 7:40 pm - 7:50 pm | Mini-Talk: Daisuke Nakane (Nagasaki University)
"Gliding machinery of Flavobacterium johnsoniae moves along the cell surface powered by protonmotive force"
|
| 7:50 pm - 7:55 pm | Discussion |
| 7:55 pm - 8:05 pm | Mini-talk: Junhua Yuan (Harvard University)
"Adaptation at the output of the chemotaxis signaling pathway"
|
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:35 pm | Judy Armitage (University of Oxford)
"Positioning of chemosensory proteins in Rhodobacter sphaeroides" |
| 8:35 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:10 pm | Lotte Sogaard-Anderson (Max Planck Institute for Terrestrial Microbiology)
"Regulation of bacterial cell polarity by small GTPases" |
| 9:10 pm - 9:20 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
