SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Session |
7:40 pm - 7:50 pm | Discussion Leader: Jason Burdick (University of Pennsylvania) |
7:50 pm - 8:30 pm | Michael Sheetz (Columbia University)
"Mechanosensing by Tropomyosin-Controlled Myosin Contractions" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:20 pm | Alexander M. Cruickshank Award Lecture: Kristi Anseth (University of Colorado)
"Advances in Dynamically Tunable Hydrogels: Cell Biology in the 4th Dimension"
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9:20 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Adhesion and Signaling |
9:00 am - 9:10 am | Discussion Leader: Andres Garcia (Georgia Tech) |
9:10 am - 9:45 am | Dave Odde (University of Minnesota)
"Simulating Cell Adhesion and Migration Mechanics"
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9:45 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:05 am | Jeanne Schwarzbauer (Princeton University)
"Control of Tissue Development by Spatial Alignment of ECM"
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11:05 am - 11:20 am | Discussion |
11:20 am - 11:55 am | Milan Mrksich (Northwestern University)
"Patterned Substrates for Stem Cell Biology" |
11:55 am - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Lauren Black (Tufts University)
"Identification of a Cryptic Peptide from Cardiac ECM to Control Cardiomyocyte Behavior"
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12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Cellular Mechanotransduction |
7:30 pm - 7:40 pm | Discussion Leader: Kristopher Killian (University of Illinois) |
7:40 pm - 8:05 pm | Sanjay Kumar (University of California - Berkeley)
"How Cells Distribute Tensile Loads Against the Extracellular Matrix"
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8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Craig Simmons (University of Toronto)
"Regulation of Mesenchymal Progenitor Cell Fate by Matrix Mechanics in Complex Environments"
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8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Robert Mauck (University of Pennsylvania)
"Aging and Differentiation Alter Nuclear Mechanobiology in Dense Connective Tissues"
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9:15 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Engineering Stem Cell Niches |
9:00 am - 9:10 am | Discussion Leader: Sharon Gerecht (Johns Hopkins University) |
9:10 am - 9:45 am | Gordana Vunjak-Novakovic (Columbia University)
"Engineering Tissue Function: Stem Cells, Native Matrix and Physical Cues"
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9:45 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:05 am | Joseph Wu (Stanford University)
"Clinical Hurdles for Tissue Repair and Regeneration" |
11:05 am - 11:20 am | Discussion |
11:20 am - 11:55 am | Nicola Elvassore (University of Padova)
"Shaping Topological, Mechanical, and Soluble Microenvironment for Stem Cell Fate Specification" |
11:55 am - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Jianping Fu (University of Michigan)
"Hippo/YAP-mediated Rigidity-Dependent Functional Motor Neuron Differentiation of Human iPSCs"
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12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Engineering Tissue Function |
7:30 pm - 7:40 pm | Discussion Leader: Ed Botchwey (Georgia Tech) |
7:40 pm - 8:10 pm | Fiona Watt (King's College London)
"Role of the Niche in Regulating Epidermal Stem Cell Fate"
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8:10 pm - 8:25 pm | Discussion |
8:25 pm - 8:55 pm | Jim Wells (Cincinnati Children's Hospital)
"Using Human Pluripotent Stem Cell-Based Approaches to Engineer Gastrointestinal Function In Vitro"
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8:55 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Deok-Ho Kim (University of Washington)
"Nano-Engineering of 3D Complex Tissues with Controllable Architecture and Function"
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9:25 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Engineering 3D Environments |
9:00 am - 9:10 am | Discussion Leader: Kristyn Masters (University of Wisconsin) |
9:10 am - 9:45 am | Claudia Fischbach (Cornell University)
"3D Culture Platforms for Studies of Tumor-Microenvironment Interactions"
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9:45 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:05 am | Dror Seliktar (Technion University)
"Semi-Synthetic Hydrogels Designed to Guide Cell Fate and Tissue Repair"
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11:05 am - 11:20 am | Discussion |
11:20 am - 11:55 am | Kevin Healy (University of California-Berkeley)
"Growth Factor Sequestering Hydrogels for Stem Cell Transplantation"
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11:55 am - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Fan Yang (Stanford University)
"Microribbon-Based Hydrogels as 3D Cell Niche: A Lego-Building Approach" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Cell Migration |
7:30 pm - 7:40 pm | Discussion Leader: Doug DeSimone (University of Virginia) |
7:40 pm - 8:10 pm | Ken Yamada (NIH)
"Cell Migration and Signaling in 3D Environments"
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8:10 pm - 8:25 pm | Discussion |
8:25 pm - 8:55 pm | Denis Wirtz (Johns Hopkins University)
"Regulation of Cell Migration by Matrix Dimension"
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8:55 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Shelly Peyton (University of Massachusetts - Amherst)
"Cell Migration and Cancer Metastasis"
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9:25 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Growth Factor and ECM Interactions |
9:00 am - 9:10 am | Discussion Leader: Linda Griffith (MIT) |
9:10 am - 9:45 am | Bill Murphy (University of Wisconsin)
"Biomaterials as the Accelerator, the Clutch, and the Brakes in Stem Cell Culture"
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9:45 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:05 am | Jeffrey Hubbell (EPFL)
"Protein Engineering Approaches to Controlling Growth Factor-ECM Interactions"
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11:05 am - 11:20 am | Discussion |
11:20 am - 11:55 am | Jennifer Cochran (Stanford University)
"Engineered Growth Factor Ligands that Promote Tissue Regeneration"
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11:55 am - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Marcy Zenobi-Wong (ETH Zurich)
"Sulfated Hydrogels for Regulating the Proliferation/Differentiation Switch in Chondrocytes"
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12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Understanding Matrix Assembly |
7:30 pm - 7:40 pm | Discussion Leader: Rebecca Carrier (Northeastern University) |
7:40 pm - 8:10 pm | Robert Mecham (Washington University)
"Extracellular Matrix Assembly: It's All About the Neighborhood"
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8:10 pm - 8:25 pm | Discussion |
8:25 pm - 8:55 pm | Shyni Varghese (University of California-San Diego)
"Physicochemical Alterations of the Extracellular Matrix: Implications in Fibrosis and Cancer Metastasis"
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8:55 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Adam Feinberg (Carnegie Mellon University)
"Multi-Scale Bottom-Up Engineering of the Extracellular Matrix" |
9:25 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |