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Signal Transduction by Engineered Extracellular Matrices (GRS)

Gordon Research Seminar

July 7 - 8, 2012
Chairs Kyle J. Lampe and Brendan Purcell

Conference Description

The Gordon Research Seminar on Signal Transduction by Engineered Extracellular Matrices is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The goal of this GRS is to promote interaction among young researchers through research presentations and scientific discussions focusing on signaling interactions between cells and their surrounding microenvironment. Trainees from biological and engineering disciplines will participate in discussions on native and synthetic extracellular matrices, cellular force transduction, matrix receptor signal transduction pathways, matrix effects on stem cell differentiation and proliferation, and tissue morphogenesis and regeneration.

Related Meeting

This GRS will be held in conjunction with the "Signal Transduction by Engineered Extracellular Matrices" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

SATURDAY
1:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmMolecular Determinants of Cell-ECM Signaling
Discussion Leaders: Karen Hirschi (Yale University) and Ema Ciucurel (University of Toronto)
3:45 pm - 4:00 pm Stephanie Seidlits (Northwestern University)
"A large-scale, real-time array to assess dynamic changes in intracellular signaling in response to biomaterial-mediated mechanical and adhesive stimuli"
4:00 pm - 4:07 pm Discussion
4:07 pm - 4:22 pm Susanta Sarkar (National Institutes of Health)
"Single-molecule Tracking of Collagenase on Native Type I Collagen Fibrils Reveals Degradation Mechanism"
4:22 pm - 4:30 pm Discussion
4:30 pm - 6:00 pmPoster Session I (Last Names beginning with A-L)
6:00 pmDinner
7:30 pm - 9:30 pmCell-ECM Interactions
Discussion Leaders: Jason Burdick (University of Pennsylvania) and Nduka Enemchukwu (Georgia Institute of Technology)
7:30 pm - 7:50 pm Darinka Klumpers (Harvard University)
"Cellular Traction Forces in 3D Tissue Constructs Lead to Patterning and Spatially Regulated Differentiation"
7:50 pm - 8:00 pm Discussion
8:00 pm - 8:20 pm Britta Trappmann (University of Pennsylvania)
"Extracellular matrix tethering regulates stem cell fate"
8:20 pm - 8:30 pm Discussion
8:30 pm - 8:50 pm Duc-Huy Nguyen (University of Pennsylvania)
"An in vitro model of angiogenesis"
8:50 pm - 9:00 pm Discussion
9:00 pm - 9:20 pm Cyrus Ghajar (Lawrence Berkeley National Lab)
"Engineering Disseminated Tumor Cell Microenvironments Reveals that Endothelial Cells Regulate Breast Tumor Dormancy"
9:20 pm - 9:30 pm Discussion
SUNDAY
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amEngineered ECMs for Tissue Repair
Discussion Leaders: Jordan Miller (University of Pennsylvania) and Rachael Oldinski (University of Vermont)
9:00 am - 9:20 am Federico Tortelli (École Polytechnique Fédérale de Lausanne)
"Fibrin matrices based on interactions between CXCL11 and extracellular matrix proteins facilitate wound repair"
9:20 am - 9:30 am Discussion
9:30 am - 9:50 am Janice Lai (Stanford University)
"Engineering cell-cell interactions in 3D for cartilage tissue engineering"
9:50 am - 10:00 am Discussion
10:00 am - 10:20 am Steven Caliari (University of Illinois)
"Collagen-glycosaminoglycan scaffolds and soluble factor presentation for directing MSC fate"
10:20 am - 10:30 am Discussion
10:30 am - 10:50 am Widya Mulyasasmita (Stanford University)
"Injectable protein-engineered hydrogels to improve cell transplantation"
10:50 am - 11:00 am Discussion
11:00 am - 12:30 pmPoster Session II (Last names beginning with M-Z)
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentor Roundtable
Karen Hirschi (Yale University), Jason Burdick (University of Pennsylvania), Sharon Gerecht (Johns Hopkins University) and Robert Mauck (University of Pennsylania)
"Funding a lab: From choosing a research direction to writing grants"
2:30 pm - 3:00 pmEvaluation Period
Fill out GRS Evaluation Forms
3:00 pmGordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm.

Contributors

Conference Links

Conference History Signal Transduction by Engineered Extracellular Matrices
Additional Fee Info

Signal Transduction by Engineered Extracellular Matrices
July 21 - 26, 2024


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