Saturday |
2:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | Laying the Foundation: 3D Matrix Patterning of Engineered Extracellular Matrices |
| Discussion Leaders: Cassady Rupert (Brown University, USA) and Rebecca Scott (University of Delaware, USA) |
3:45 pm - 4:00 pm | Lisa Sawicki (University of Delaware, USA) "Tunable Hydrogels to Understand the Role of the Microenvironment in Regulating Breast Cancer Dormancy and Recurrence" |
4:00 pm - 4:05 pm | Discussion |
4:05 pm - 4:20 pm | Bagrat Grigoryan (Rice University, USA) "Stereolithography of Engineered Tissues Containing Interpenetrating Vascular Networks" |
4:20 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Molecular Mechanisms of Cell-ECM Signaling: From Matrix Molecules to Mechanics |
| Discussion Leaders: Victor Hernandez-Gordillo (Massachusetts Institute of Technology, USA) and Sharvari Sathe (National University of Singapore, Singapore) |
7:30 pm - 7:50 pm | Ana Porras (University of Wisconsin-Madison, USA) "Creation of Glycosaminoglycan-Enriched Environments to Study Aortic Valve Pathobiology" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Lauren Jansen (University of Massachusetts Amherst, USA) "Marrow Tissue Induces Sensitivity to IL-6 and
VEGF-A in Mesenchymal Stem Cells During Breast-to-Bone Metastasis" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Vincent Fitzpatrick (Laboratoire des Matériaux et du Génie Physique, Grenoble Institute of Technology, France) "Signal Mingle: Micropatterns of BMP-2 and Fibronectin on Soft Biopolymeric Films Regulate Myoblast Spreading and SMAD Signaling" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Laralynne Przybyla (University of California, San Francisco, USA) "Matrix Tension Directs Tissue-Level Organization to Prime Embryonic Stem Cells for Mesoderm Differentiation" |
9:20 pm - 9:30 pm | Discussion |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Engineered Microenvironments to Parse Cell-Cell Communication |
| Discussion Leaders: Evan Chiswick (Massachusetts Institute of Technology, USA) and Alexander Zevin (University of Washington, USA) |
9:00 am - 9:20 am | Jorge Valdez (Massachusetts Institute of Technology, USA) "Measurement of Local Epithelial-Stromal Communication Enabled by On-Demand Sortase A-Mediated Dissolution of Synthetic, Modular, Extracellular Matrix" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Marina Shumakovich (University of Maryland, USA) "Microfluidic Models to Understand Tumor Cell Interactions with the Brain Microenvironment at the Blood-Brain Barrier" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | David Belair (U.S. Environmental Protection Agency, USA) "Engineered Three-Dimensional Multicellular Culture Model to Recapitulate Morphogenetic Fusion Using Human Cells" |
10:20 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Alexander Buffone (University of Pennsylvania, USA) "Migration Against the Direction of Flow Is LFA-1 Dependent in a Human Hematopoietic Stem Cell Line" |
10:50 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Mentorship Component: Career Panel |
| Discussion Leaders: Christi Cook (Massachusetts Institute of Technology, USA) and Chris Madl (Stanford University, USA) |
1:30 pm - 2:30 pm | Panel Discussion |
| "Exploring Careers in Academia, Government, and Industry" |
|
- Shannon Hughes (Division of Cancer Biology, National Cancer Institute, NIH, USA)
- Shelly Peyton (University of Massachusetts Amherst, USA)
- Manu Platt (Georgia Institute of Technology, USA)
- Serena Silver (Novartis Institutes for BioMedical Research, USA)
|
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |