Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Building Multicellular Structures during Development
Discussion Leader: Robert Huebner (University of Texas at Austin, United States)
3:45 pm - 4:20 pm
Jennifer Zallen (Memorial Sloan Kettering Cancer Center, United States)
"Shaping the Embryo: Cellular Dynamics in Development"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Basic Biomechanics of Cell Adhesion Signaling
Discussion Leader: Lotte van den Goor (University of Michigan, United States)
7:30 pm - 7:45 pm
Jooske Monster (University Medical Centre Utrecht, The Netherlands)
"Clustering of the Adherens Junction Complex by ß-Catenin Condensation"
7:45 pm - 7:55 pm
Discussion
7:55 pm - 8:10 pm
Martina Lerche (National Institutes of Health, United States)
"Ligand-Specific Delivery of Newly Synthesized Integrins Regulates Focal Adhesions"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
Jennifer Landino (University of Michigan, United States)
"Neighbor Cell Actomyosin Contractility Modulates Epithelial Cytokinesis"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:00 pm
Adam Stevens (University of California San Francisco, United States)
"Programmable Cellular Interactions Using Synthetic Adhesion Molecules"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Fernando Valencia (University of Toronto, Canada)
"Forces of Change: Mechanical Activation of Dia1 at Focal Adhesions Protects the Cytoskeleton from Damage, and Facilitates Stress Fiber Repair"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Biomedical Applications of Cell Adhesion Signaling
Discussion Leaders: Jonas Aretz (Max Planck Institute of Biochemistry, Germany)
9:00 am - 9:15 am
Vera Janssen (Amsterdam UMC, The Netherlands)
"BAR-Protein Mediated VE-Cadherin Trafficking Balances Forces Between Endothelial Cells During Angiogenesis"
9:15 am - 9:25 am
Discussion
9:25 am - 9:40 am
Timo Kohler (University of Cambridge, United Kingdom)
"Cells in Gels - Identification of Plakoglobin as an Evolutionary Conserved Mechanosensitive Regulator of Naïve Pluripotency"
9:40 am - 9:50 am
Discussion
9:50 am - 10:05 am
James Conway (University of Turku, Finland)
"Dynamic Regulation of Integrin Beta1 Phosphorylation Supports Invasive Breast Cancer Progression"
10:05 am - 10:15 am
Discussion
10:15 am - 10:30 am
Dayoung Kim (Fred Hutchinson Cancer Center, United States)
"N-Cadherin Regulates Collective Glioma Cell Migration and Invasion"
10:30 am - 10:40 am
Discussion
10:40 am - 10:55 am
Yuou Wang (Northwestern University, United States)
"Alpha-Catenin Mechanosensitivity as a Route to Cytokinesis Failure during Epithelial Injury-Induced Polyploidization"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Job Search after Your PhD/Postdoc
Discussion Leaders: Camilla Schinner (University of Basel, Switzerland)
1:30 pm - 2:30 pm
Panel Discussion
Job Search after Your PhD/Postdoc
Bob Goldstein (University of North Carolina at Chapel Hill, United States)
Karin Wang (Temple University, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes