Conference Description
The Single-Cell Cancer Biology GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.
Cancer is a complex and dynamic biological system whereby individual cells comprise elemental units of evolutionary selection. As such, comprehensive analysis and interpretation of cancer properties require precise investigation at single cell resolution. Several fundamental questions in cancer biology remain poorly understood, including transition from pre-malignancy to tumor, clonal evolution & plasticity, intra-tumor heterogeneity, tumor-stroma interaction, mechanisms for metastasis, therapeutic resistance and the immune microenvironment. These questions have been difficult to address through characterization of bulk tissue samples, which are limited to providing an average signal from a complex population of cells. Nevertheless, the field is witnessing a rapid advance in single cell omics and imaging technologies. These technologies provide a powerful approach to address these questions.
This Gordon Research Conference is the only forum dedicated to Single Cell Cancer Biology. It brings together leading researchers with different background that use single cell technologies to address a range of problems in basic cancer biology, translational, and clinical oncology. The meeting features sessions on pre-malignancies and clonal evolution, intra-tumor heterogeneity, cell-cell interactions in tumor microenvironment, technical advances in single cell protocols and computational methods for data analysis and modeling, single cell technologies in clinical practice, liquid biopsy, and single-cell multi-omics. By fostering close interactions and active discussion among practitioners from many disciplines and from both academia and industry, we aim to foster leadership for the coming decade of rapid progress in research and applications relevant to Single Cell Cancer Biology.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by February 10, 2024. Please check back for updates.
Pre-Malignancies and Early Stage Tumors
Discussion Leaders
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Mariella Filbin (Dana-Farber Cancer Institute/Boston Children's Hospital, United States)
Speakers
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Joan Brugge (Harvard Medical School, United States)
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Elli Papaemmanouil (Memorial Sloan Kettering Cancer Center, United States)
Multi-Omic Analysis and Cellular Plasticity
Discussion Leaders
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Joan Brugge (Harvard Medical School, United States)
Speakers
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Bradley Bernstein (Harvard University / Dana Farber Cancer Institute, United States)
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Caleb Lareau (Memorial Sloan Kettering Cancer Center, United States)
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Linghua Wang (The University of Texas MD Anderson Cancer Center, United States)
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Joseph Chan (Memorial Sloan Kettering Cancer Center, United States)
Perturbations and Single Cell Readouts
Discussion Leaders
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Devon Lawson (University of California, Irvine, United States)
Speakers
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Tuomas Tammela (Memorial Sloan Kettering Cancer Center, United States)
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Jellert Gaublomme (Columbia University, United States)
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Alex Shalek (MIT, Broad & Ragon, United States)
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Weiyi Peng (University of Houston, United States)
Tumor Ecosystems and Microenvironments
Discussion Leaders
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Rachel Karchin (Johns Hopkins University, United States)
Speakers
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Mariella Filbin (Dana-Farber Cancer Institute/Boston Children's Hospital, United States)
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Kai Tan (University of Pennsylvania, United States)
Advances in Spatial Technologies
Discussion Leaders
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Jellert Gaublomme (Columbia University, United States)
Speakers
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Sanja Vickovic (New York Genome Center, Columbia University, SciLifeLab, United States)
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Fei Chen (Broad Institute, United States)
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Jean Fan (Johns Hopkins University, United States)
Immune Recognition in Cancer
Discussion Leaders
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Caleb Lareau (Memorial Sloan Kettering Cancer Center, United States)
Speakers
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Benjamin Greenbaum (Memorial Sloan Kettering Cancer Center, United States)
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Rachel Karchin (Johns Hopkins University, United States)
Computational Methods
Discussion Leaders
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Jean Fan (Johns Hopkins University, United States)
Speakers
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Ben Raphael (Princeton University, United States)
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Joshua Campbell (Boston University, United States)
Genetic Evolution and Therapeutic Resistance
Discussion Leaders
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Nicholas Navin (University of Texas MD Anderson Cancer Center, United States)
Speakers
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Nicholas McGranahan (UCL Cancer Institute, University College London, United Kingdom)
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Timour Baslan (University of Pennsylvania, United States)
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Andrea Sottoriva (Human Technopole, Italy)
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Charles Rudin (Memorial Sloan Kettering Cancer Center, United States)
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Peter Van Loo (The University of Texas MD Anderson Cancer Center, United States)
Invasion and Metastasis
Discussion Leaders
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Andrea Sottoriva (Human Technopole, Italy)
Speakers
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Karuna Ganesh (Memorial Sloan Kettering Cancer Center, United States)
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Adrienne Boire (Memorial Sloan Kettering Cancer Center, United States)
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Nicholas Navin (University of Texas MD Anderson Cancer Center, United States)
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Ashley Laughney (Weill Cornell Medicine, United States)
The GRC Power Hourâ„¢
Organizers
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Devon Lawson (University of California, Irvine, United States)