| SUNDAY |
| 4:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 8:00 pm | Welcome by the Chairs / Introductory Comments by GRC Site Staff |
| 8:00 pm - 9:30 pm | Frontiers of Research in Staphylococci |
| 8:00 pm - 8:15 pm | Discussion Leader: Richard A. Proctor (University of Wisconsin, Madison) |
| 8:15 pm - 8:45 pm | Richard Novick (New York University Medical Center, New York)
"Staphylococcal virulence and its regulation" |
| 8:45 pm - 8:55 pm | Discussion |
| 8:55 pm - 9:20 pm | Sharon Peacock (Mahidol University, Bangkok)
"Staphylococcus aureus disease and drug resistance in rural Asia" |
| 9:20 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Animal models, virulence, and host defense evasion |
| 9:00 am - 9:10 am | Discussion Leader: Philippe Moreillon (University of Lausanne, Switzerland) |
| 9:10 am - 9:40 am | Yok-Ai Que (University of Lausanne)
"The use of animal models to study Staphylococcus aureus pathogenesis" |
| 9:40 am - 9:55 am | Discussion |
| 9:55 am - 10:10 am | Concise Communication: Suzanne Rooijakkers (University of Utrecht, NL)
"Complement evasion by Staphylococcus aureus" |
| 10:10 am | Group Photo / Coffee Break |
| 11:00 am - 11:30 am | Michael D Menger (University of Saarland, Homburg, Germany)
"Characteristics and mechanisms of staphylococcal interactions with microvascular endothelium in vivo" |
| 11:30 am - 11:40 am | Discussion |
| 11:45 am - 12:15 pm | Frank D Lowy (Columbia University, New York)
"Development of Animal Models to Study the Pathogenesis and Prevention of Ventricular Assist Device Infections" |
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | Novel strategies to combat staphylococcal infections |
| 5:30 pm - 5:35 pm | Discussion Leader: Hans Georg Sahl (University of Bonn, Germany) |
| 5:35 pm - 6:00 pm | Heike Brötz-Oesterhelt (AiCuris, Wuppertal, Germany)
"Dysregulation of bacterial Clp-protease by acyldepsipeptide antibiotics" |
| 6:00 pm - 6:10 pm | Discussion |
| 6:10 pm - 6:20 pm | Concise Communication: Paul Dunman (University of Nebraska, Omaha NE)
"MRSA vs. MRSA (Messenger RNA Stabilizing Antimicrobials)" |
| 6:20 pm - 6:45 pm | Annaliesa Anderson (Merck, West Point PA)
"Epidemiology of antibodies to S. aureus antigens in natural populations and implications towards the development of an effective S. aureus vaccine" |
| 6:45 pm - 6:55 pm | Discussion |
| 6:55 pm - 7:20 pm | Neeloffer Mookherjee (University of British Columbia, Canada)
"Novel cationic immunomodulatory and antibacterial host defence peptides as new treatments for antibiotic resistant infections" |
| 7:20 pm - 7:30 pm | Discussion |
| 8:00 pm | Dinner |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Staphylococcal virulence factors and host cell interaction |
| 9:00 am - 9:10 am | Discussion Leader: Magnus Hook (Texas A&M University System, Houston) |
| 9:10 am - 9:40 am | Heiko Herwald (University of Lund, Sweden)
"Kinin receptor expression during Staphylococcus aureus infection" |
| 9:40 am - 10:00 am | Discussion |
| 10:00 am | Coffee Break |
| 10:30 am - 10:45 am | Concise Communication: Rong Wang (NIAID, NIH, Hamilton Montana)
"Phenol-soluble modulins: primary virulence determinants of community-associated MRSA" |
| 10:45 am - 11:15 am | Dominique Missiakas (University of Chicago, Chicago IL)
"Staphylococcus aureus strategies of evading host immune responses" |
| 11:15 am - 11:35 am | Discussion |
| 11:35 am - 12:05 pm | Triantafyllos Chavakis (National Cancer Institute, Bethesda, MD, USA)
"Regulation of the immune response by S. aureus Eap" |
| 12:05 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | Immune mechanisms in staphylococcal disease |
| 5:30 pm - 5:35 pm | Discussion Leader: Jean C. Lee (Harvard Medical School, Boston) |
| 5:35 pm - 6:00 pm | Victor Nizet (University of California, San Diego CA)
"Probing the interaction of Gram-positive pathogens with host innate defenses for novel therapeutic targets" |
| 6:00 pm - 6:10 pm | Discussion |
| 6:10 pm - 6:20 pm | Concise Communication: Maren von Koeckritz-Blickwede (Helmholtz Institute for Infection Research, Braunschweig, Germany)
"C5a protects from Staphyloccus aureus -induced sepsis: a critical role for C5L2" |
| 6:20 pm - 6:45 pm | Tammy Kielian (University of Arkansas, Little Rock AR)
"Immune Responses to S. aureus in the Central Nervous System" |
| 6:45 pm - 6:55 pm | Discussion |
| 6:55 pm - 7:20 pm | Jos van Strijp (University Medical Center, Utrecht, Netherlands)
"Innate Immune Evasion by Staphylococci" |
| Discussion |
| 8:00 pm | Dinner |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | System biology of staphylococci |
| 9:00 am - 9:10 am | Discussion Leader: Jodi Lindsay (University of London, London UK) |
| 9:10 am - 9:40 am | Brice Felden (University of Rennes, Rennes, France)
"Elucidating the functions of some of the newly identified non conventional ribonucleic acids expressed by Staphylococcus aureus" |
| 9:40 am - 10:00 am | Discussion |
| 10:00 am | Coffee Break |
| 10:30 am - 10:45 am | Concise Communication: Swantje Reiss (University of Greifswald, Germany)
"Global characterization of the mupirocin induced stringent response in Staphylococcus aureus using the proteomic and transcriptomic approach" |
| 10:45 am - 11:15 am | Matthias Heinemann (ETH Zurich, Switzerland)
"Systems biology approaches towards understanding S. aureus metabolism" |
| 11:15 am - 11:35 am | Discussion |
| 11:35 am - 12:05 pm | Makoto Kuroda (University of Tsukuba, Japan)
"In vivo expression of cell surface proteins in S. aureus" |
| 12:05 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | Bacterial physiology and metabolism |
| 5:30 pm - 5:35 pm | Discussion Leader: Greg Somerville (University of Nebraska, Lincoln NE) |
| 5:35 pm - 6:00 pm | Paul Williams and Simon Clarke (University of Nottingham, Nottingham, UK)
"Quorum sensing, metabolism and cross-talk in Staphylococcus aureus" |
| 6:00 pm - 6:10 pm | Discussion |
| 6:10 pm - 6:20 pm | Concise Communication: Iris Fedtke (University of Tuebingen, Germany)
"Staphylococcus aureus ypfP mutant with strongly reduced lipoteichoic acid (LTA) content: LTA governs bacterial surface properties and autolysin activity" |
| 6:20 pm - 6:45 pm | Friedrich Goetz (University of Tuebingen, Tuebingen, Germany)
"Why are pathogenic staphylococci so lysozyme resistant?" |
| 6:45 pm - 6:55 pm | Discussion |
| 6:55 pm - 7:20 pm | Dorte Frees (University of Copenhagen, Copenhagen, Denmark)
"Regulated proteolysis controls vital processes in Staphylococcus aureus" |
| 7:20 pm - 7:30 pm | Discussion |
| 8:00 pm | Dinner |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Biofilm growth of staphylococci: implications on regulation and metabolism |
| 9:00 am - 9:10 am | Discussion Leader: Dietrich Mack (University of Wales, Swansea, UK) |
| 9:10 am - 9:40 am | Johannes K.-M. Knobloch (University of Luebeck, Luebeck, Germany)
"Regulation of biofilm formation and other putative virulence factors in Staphylococcus epidermidis" |
| 9:40 am - 10:00 am | Discussion |
| 10:00 am - 10:15 am | Concise Communication: Alexander Horswill (University of Iowa)
"Staphylococcus aureus autoinducing peptides control biofilm detachment" |
| 10:15 am - 10:30 am | Concise Communication: Holger Rohde (University of Hamburg, Hamburg, Germany)
"The Accumulation associated protein (Aap) of Staphylococcus epidermidis: Identification and characterization of interaction partners involved in biofilm formation" |
| 10:30 am | Coffee Break |
| 11:00 am - 11:15 am | Concise Communication: Tarek Msadek (Institut Pasteur, Paris, France)
"New insights into the YycG/YycF essential signal transduction pathway reveal a major role in controlling cell wall degradation and biofilm formation in Staphylococcus aureus" |
| 11:15 am - 11:30 am | Concise Communication: Rebecca M Corrigan (Trinity College, Dublin, Ireland)
"The role of Staphylococcus aureus surface protein SasG in adherence and biofilm formation" |
| 11:30 am - 12:00 pm | Kimberly Jefferson (Virginia Commonwealth University, Richmond VA)
"Post-transcriptional regulation of the intercellular adhesin locus in Staphylococcus aureus" |
| 12:00 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 6:30 pm | Controversies/Hot Topics |
| Discussion Leaders: Georg Peters (University of Muenster, Muenster, Germany) and Steven J Projan (Wyeth Research, Cambridge MA) |
| 5:30 pm - 6:30 pm | Speaker: TBA |
| 6:30 pm - 7:30 pm | Poster Review |
| Discussion Leaders: Kenneth W Bayles (University of Nebraska, Lincoln NE) and Barry N Kreiswirth (Public Health Research Institute, Newark NJ) |
| 6:20 pm - 7:30 pm | Topics chosen from poster presenters: TBA |
| 7:30 pm - 8:00 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 8:00 pm | Dinner |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
