Saturday |
1:30 pm - 4:30 pm | Arrival and Check-in |
3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:15 pm - 4:00 pm | In Vivo Models of Staphylococcal Disease |
| Discussion Leaders: Tammy Kielian (University of Nebraska Medical Center, USA) and Kipyegon Kitur (Columbia University, USA) |
3:15 pm - 3:20 pm | Opening Remarks |
3:20 pm - 3:35 pm | Helene Van de Vyver (Institute for Medical Microbiology, University Hospital Münster, Germany) "Set Up and MR-PET Imaging of a Staphylococcus aureus Vascular Graft Infection Model in Mice" |
3:35 pm - 3:40 pm | Discussion |
3:40 pm - 3:55 pm | Dennis Jones (Massachusetts General Hospital / Harvard Medical School, USA) "Characterization of Lymphatic Contraction During Staphylococcus aureus Infection" |
3:55 pm - 4:00 pm | Discussion |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | Toxin-Mediated Staphylococcal Disease |
| Discussion Leaders: Simon Foster (University of Sheffield, United Kingdom), Eric Skaar (Vanderbilt University, USA) and Kimberley Painter (Imperial College London, United Kingdom) |
5:30 pm - 5:45 pm | Lauren Popov (Stanford University School of Medicine, USA) "The Adherens Junctions Control Susceptibility to Staphylococcus aureus Alpha-Toxin Virulence" |
5:45 pm - 5:50 pm | Discussion |
5:50 pm - 6:05 pm | Stephen Nutbeam-Tuffs (University of Edinburgh, United Kingdom) "Staphylococcal Enterotoxin-Like Toxin X (SElX) Binds to Neutrophils in a Sialic Acid Dependent Manner and Inhibits Neutrophil Function" |
6:05 pm - 6:10 pm | Discussion |
6:10 pm - 6:25 pm | Tyler Scherr (University of Nebraska Medical Center, USA) "Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin" |
6:25 pm - 6:30 pm | Discussion |
| Mentorship Component: Career Development Advice and Support |
6:30 pm - 6:45 pm | Angelika Grundling (Imperial College London, United Kingdom) "A European Perspective" |
6:45 pm - 6:50 pm | Discussion |
6:50 pm - 7:05 pm | Tammy Kielian (University of Nebraska Medical Center, USA) "A USA Perspective" |
7:05 pm - 7:10 pm | Discussion |
7:10 pm - 7:25 pm | Steve Renshaw (University of Sheffield, United Kingdom) "A Clinician Scientist Perspective" |
7:25 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Keynote Session: Signals, Regulators and Toxins / Staphylococcal Biology |
| Discussion Leaders: Jos Van Strijp (University Medical Center Utrecht, The Netherlands), Tammy Kielian (University of Nebraska Medical Center, USA) and Kipyegon Kitur (Columbia University, USA) |
9:00 am - 9:45 am | Victor Torres (New York University School of Medicine, USA) "Signals, Regulators, and Toxins Involved in the Lethality of Staphylococcus aureus Bloodstream Infection" |
9:45 am - 10:00 am | Discussion |
10:00 am - 10:15 am | Andy Weiss (University of South Florida, USA) "Influence of the Small RNAP Subunits on Staphylococcus aureus Promoter Selectivity and Virulence" |
10:15 am - 10:20 am | Discussion |
10:20 am - 10:35 am | Victoria Lund (University of Sheffield, United Kingdom) "Growth and Division in Staphylococcus aureus" |
10:35 am - 10:40 am | Discussion |
10:40 am - 10:55 am | Derek Moormeier (University of Nebraska Medical Center, USA) "Temporal and Stochastic Control of Staphylococcus aureus Biofilm Development" |
10:55 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Host Pathogen Interactions |
| Discussion Leaders: Eric Skaar (Vanderbilt University, USA) and Kimberley Painter (Imperial College London, United Kingdom) |
1:30 pm - 1:45 pm | John Leech (Trinity College Dublin, Ireland) "IL-10 Production by Innate Cells Plays Critical Protective Roles During Staphylococcus aureus Colonisation and Infection" |
1:45 pm - 1:50 pm | Discussion |
1:50 pm - 2:05 pm | Fermin Guerra (Montana State University, USA) "Staphylococcus aureus SaeR/S-Regulated Factors Modulate Interferon-Gamma and IL-17 Production to Advance Skin Pathogenesis" |
2:05 pm - 2:10 pm | Discussion |
2:10 pm - 2:25 pm | Nienke de Jong (UMC Utrecht, The Netherlands) "Identification of a New Staphylococcal Myeloperoxidase (MPO) Inhibitor" |
2:25 pm - 2:30 pm | Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |