Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Life and Death of Persister Cells
Discussion Leaders: Casey Gries (University of Nebraska Medical Center, USA) and Simon Heilbronner (University of Tuebingen, Germany)
3:45 pm - 4:20 pm
Kim Lewis (Northeastern University, USA)
"Life and Death of Persister Cells"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Staphylococcal Toxins and Virulence Factors / Host-Pathogen Interactions
Discussion Leaders: Emma Boldock (University of Sheffield, United Kingdom), Aimee Wilde (Vanderbilt University, USA), Deena Altman (Icahn School of Medicine at Mount Sinai, USA) and Kyle Buchan (University of Sheffield, United Kingdom)
7:30 pm - 7:45 pm
Xiaogang Wang (Brigham and Women's Hospital / Harvard Medical School, USA)
"Biogenesis of Extracellular Vesicles from S. aureus and Their Application as a Vaccine Platform"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Sarah Baines (University of Melbourne, Australia)
"Convergent Adaptation of qacA-Containing Plasmids Within a Prevalent Hospital Lineage of Methicillin-Resistant Staphylococcus aureus Associated with Enhanced Chlorhexidine Tolerance"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Evelien Berends (New York University School of Medicine, USA)
"Staphylococcus aureus Targets Dendritic Cells and Hinders Development of Adaptive Immunity via Leukocidin AB"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Julia Uebele (Paul Ehrlich Institute, Germany)
"(Re-)Balancing of T Cell Memory to Staphylococcus aureus by Delivery of In Vitro Transcribed Antigens"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Rob van Dalen (University Medical Center Utrecht, The Netherlands)
"The C-Type Lectin Receptor Langerin on Skin Langerhans Cells Interacts with Wall Teichoic Acid of Staphylococcus aureus "
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Sheila Thomas (Center for Infectious and Inflammatory Diseases, Texas A&M Institute of Biosciences & Technology, USA)
"Staphylococcus aureus von-Willebrand Factor-Binding Protein Interacts with Fibrinogen via Unique Binding Sites"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Staphylococcal Metabolism / In Vivo Staphylococcal Disease Models
Discussion Leaders: Mariya Goncheva (The Roslin Institute, University of Edinburgh, United Kingdom), Amy Richards (University of Edinbugh, United Kingdom), Wenqi Yu (University of Chicago, USA) and Jessica Sheldon (Vanderbilt University Medical Center, USA)
9:00 am - 9:15 am
Aimee Wilde (Vanderbilt University, USA)
"The Skeletal Environment Mediates Staphylococcus aureus Metabolic Processes In Vivo "
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Christopher Schuster (Imperial College London, United Kingdom)
"TN-seq Reveals Salt Stress Tolerance Genes in Staphylococcus aureus "
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
McKenzie Lehman (University of Nebraska Medical Center, USA)
"Amino Acid Metabolism Is Important During a Staphylococcus aureus Skin Abscess Infection"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Kyle Buchan (University of Sheffield, United Kingdom)
"Building a Humanised C5a Receptor Model of Staphylococcus aureus Infection"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Rachel Kratofil (University of Calgary, Canada)
"Investigating a Mechanism of Monocyte Conversion During a Localized Staphylococcus aureus Skin Infection"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Kayan Tam (New York University School of Medicine, USA)
"Fighting Toxins with Toxins - Exploiting the Leukocidins as Potential Targets for Anti-Staphylococcus aureus Vaccine"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel
Discussion Leaders: William Beavers (Vanderbilt University, USA) and Christopher Schuster (Imperial College London, United Kingdom)
1:30 pm - 2:30 pm
Panel Discussion
Career Development
Jim Cassat (Vanderbilt University Medical Center, USA)
Bettina Loeffler (Jena University Hospital, Germany)
Amanda Oglesby-Sherrouse (University of Maryland, Baltimore, USA)
Bret Sellman (MedImmune, LLC, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
