Saturday
1:30 pm - 4:30 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Keynote Session: S. aureus Interacting with the Nasal Microbiota
Discussion Leaders: Pipat Piewngam (National Institutes of Health, USA) and Mariya Goncheva (The University of Western Ontario, Canada)
3:15 pm - 3:45 pm
Katherine Lemon (The Forsyth Institute, USA)
"Nosing Around: Lead with Curiosity"
3:45 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Staphylococcal Phages and Horizontal Gene Transfer / Gene Regulation Pathways
Discussion Leaders: David Gerlach (University of Tübingen, Germany), Gonzalo Yebra (The Roslin Institute, University of Edinburgh, United Kingdom), Selvi Ersoy (Los Angeles Biomedical Research Institute, USA) and Stefano Giulieri (University of Melbourne, Australia)
5:30 pm - 5:45 pm
Abraham Moller (Emory University, USA)
"Population Genomic and Evolutionary Studies of Phage Resistance and Host Range in Staphylococcus aureus "
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
Katrin Schilcher (University of Colorado Anschutz Medical Campus, USA)
"Lipoprotein-Derived Linear Signal Peptides: Unravelling Their Biological Potential in Staphylococcus aureus Pathogenesis"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
Rebecca Mekler (University of St Andrews, United Kingdom)
"Species-Wide Investigation of Differential 6-Methyl-Adenine (6mA) DNA Methylation by Sau1 Type I Restriction-Modification in Staphylococcus aureus "
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Stephanie Marroquin (University of South Florida, USA)
"MroQ Is a Novel Abi-Domain Protein that Influences Virulence Gene Expression in Staphylococcus aureus via Modulation of Agr Activity"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Aura Ramirez (University of Arkansas for Medical Sciences, USA)
"Exploiting Correlations Between Protein Abundance and the Functional Status of saeRS and sarA to Identify Virulence Factors of Potential Importance in the Pathogenesis of S. aureus Osteomyelitis"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Brittney Gimza (University of South Florida, USA)
"Exploring the Regulation of Secreted Proteases and Their Role in Controlling Disease Progression in Staphylococcus aureus "
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Staphylococcal Host-Pathogen Interactions / Adaptation to Persistence
Discussion Leaders: Stephen Tuffs (University of Western Ontario, Canada), Katelynn Brann (University of Arkansas for Medical Sciences, USA), Christian Jenul (University of Colorado Anschutz Medical Campus, USA) and Wei Ping Teoh (Loyola University Chicago, USA)
9:00 am - 9:15 am
Srikanth Mairpady Shambat (University Hospital Zurich, Switzerland)
"Staphylococcal Alpha-Toxin Induces Fractalkine Release via ADAM10 Activity and Alters Monocyte Functional Response in the Lung Mucosa During Infection"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Maksym Bobrovskyy (The University of Chicago, USA)
"Role of the Type 7b Secretion System (T7bSS) During Staphylococcus aureus Colonization and Invasive Disease"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Ching Yang (Nationwide Children's Hospital / The Ohio State University, USA)
"Neutrophils Are Essential in Antibody-Mediated Protection in a Mouse Model of Staphylococcus aureus Skin and Soft Tissue Infection"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Andrew Monteith (Vanderbilt University, USA)
"Calprotectin Modulates Neutrophil Function Increasing the Susceptibility of Lupus Patients to Staphylococcus aureus Infections"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Helene Marbach (University of Veterinary Medicine Vienna, Austria)
"S. aureus Host Adapation During a Chronic Bovine Intramammary Infection Is linked to a SigB-Deficient Phenotype"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Carlos Suligoy (Universidad de Buenos Aires, Argentina)
"Staphylococcus aureus from a Chronic Infection Site Regains Capsule Polysaccharide (CP) Expression Regardless of Agr Dysfunction After Passage Through a Mouse Model of Bacteriemia"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Multiple Routes to a Successful Scientific Career
Discussion Leaders: Rob van Dalen (UMC Utrecht / Universitätsklinikum Tübingen, Germany) and Joshua Lensmire (Michigan State University, USA)
1:30 pm - 2:30 pm
Panel Discussion
Multiple Routes to a Successful Scientific Career
Annaliesa Anderson (Pfizer Vaccine Research and Development, USA)
Seth Scanlon (AAAS Science International, Inc., United Kingdom)
Katherine Lemon (The Forsyth Institute, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes