Saturday |
2:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | Keynote Session: Exploring the Intersection of Stem Cell and Cancer Biology |
| Discussion Leader: Jessie Brown (New York University Medial Center, USA) |
3:45 pm - 4:20 pm | Tannishtha Reya (University of California, San Diego, USA) "The Stem Cell Paradigm in Development and Cancer" |
4:20 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Seeing Is Believing - Imaging Stem Cell Populations |
| Discussion Leader: Julia Frede (University of Cambridge, United Kingdom) |
7:30 pm - 7:45 pm | Frank Bos (University of California, San Francisco, USA) "Single Cell Resolution of Morphological Changes in Hemogenic Endothelium" |
7:45 pm - 7:50 pm | Discussion |
7:50 pm - 8:05 pm | Saskia Ellenbroek (Hubrecht Institute, The Netherlands) "Intravital Imaging of (Cancer) Stem Cell Dynamics" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:25 pm | Hugo Snippert (UMC Utrecht, The Netherlands) "Life and Death in Patient-Derived Colorectal Cancer Organoids" |
8:25 pm - 8:30 pm | Discussion |
| Many Approaches for Big Questions in Stem Cell Biology |
8:30 pm - 8:35 pm | Jeevisha Bajaj (Uninversity of California, San Diego, USA) "CD98 Mediated Adhesive Signaling in Acute Myelogenous Leukemia" |
8:35 pm - 8:40 pm | Seerat Bajwa (Leibniz Institute for Age Research, Germany) "DNA Damage, Aging and Immunity" |
8:40 pm - 8:45 pm | Martin Burkhalter (Leibniz-Institute for Age Research, Germany) "Elevated Hedgehog Activity Impairs DNA Damage Responses in Hematopoietic Stem and Progenitor Cells During Aging" |
8:45 pm - 8:50 pm | Evelyn Fessler (Academic Medical Center, The Netherlands) "Endothelial Cells Induce Cancer Stem Cell Features in Fully Differentiated Glioblastoma Cells via bFGF" |
8:50 pm - 8:55 pm | Mara Gilardi (IRCCS Istituto Ortopedico Galeazzi, Italy) "Investigation of Bone Metastases Through Human Organ Specific In Vitro Models" |
8:55 pm - 9:00 pm | Nicholas Gomez (University of North Carolina, Chapel Hill, USA) "The Chromatin Landscape of Stem Cells Confers a Permissive Environment for Cancer Development" |
9:00 pm - 9:05 pm | Laura Pisarsky (University of Basel, Switzerland) "VEGF-Mediated Angiogenesis Links EMT-Induced Cancer Stemness to Tumor Initiation" |
9:05 pm - 9:10 pm | Erin Simonds (University of California, San Francisco, USA) "A Functionally-Defined Primitive Cell Population in Acute Myeloid Leukemia Has Clinical Prognostic Value" |
9:10 pm - 9:15 pm | Luca Tiberi (Universite Libre de Bruxelles, Belgium) "A BCL6/BCOR/SIRT1 Complex Triggers Neurogenesis and Suppresses Medulloblastoma by Repressing Sonic Hedgehog Signaling" |
9:15 pm - 9:20 pm | Sarah Wu (MD Anderson Cancer Center, USA) "Investigating the Roles of p63 Isoforms in Lung Stem Cell Compartments and Lung Tumorigenesis" |
9:20 pm - 9:30 pm | General Discussion |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Epigenetics and Environment in Stem Cell Biology |
| Discussion Leader: Ali Baig (Leibniz Institute for Age Research - FLI, Germany) |
9:00 am - 9:15 am | Tanay Bhatt (Institute for Stem Cell and Regenerative Medicine, India) "Deciphering the Epigenetic Regulation of Caspase-8 in Wound-Healing and Cancer" |
9:15 am - 9:20 am | Discussion |
9:20 am - 9:35 am | Yaiza del Pozo Martin (Cancer Research UK, United Kingdom) "Mesenchymal Status Promotes Metastatic Colonization via a Cancer Cell-Stroma Crosstalk Which Uncouples EMT and Stemness" |
9:35 am - 9:40 am | Discussion |
9:40 am - 9:55 am | Dan Landau (Broad Institute, USA) "Genetic and Epigenetic Determinants of Chronic Lymphocytic Leukemia Evolution" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:15 am | Elen Torres (Helmholtz Zentrum Muenchen, Germany) "New Insights into the Mechanism of Tumor Formation Driven by Sox2: The Role of the Extracellular Matrix and Markers of Tumor Prognosis" |
10:15 am - 10:20 am | Discussion |
10:20 am - 10:35 am | Juli Unternaehrer (Loma Linda University, USA) "The Epithelial-Mesenchymal Transition Factor Snail Inhibits the Tumor Suppressor microRNA let-7" |
10:35 am - 10:40 am | Discussion |
10:40 am - 10:55 am | Cheryl Zimberlin (Academic Medical Centre Amsterdam, The Netherlands) "HDAC1 and HDAC2 Collectively Regulate Intestinal Stem Cell Homeostasis" |
10:55 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Mentorship Component: I've Finished My Training. Now What? |
| Discussion Leader: Andrew White (Cornell University, USA) |
1:30 pm - 2:30 pm | Panel Discussion |
|
- Lenhard Rudolph (Leibniz-Institute for Age Research, Germany)
- Leonard Zon (HHMI / Boston Children's Hospital, USA)
- Tannishtha Reya (University of California, San Diego, USA)
|
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |