Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Self-Renewal and Differentiation: Lessons From Being a Postdoc to a Professor
Discussion Leaders: Clara Cano (UCLA, United States) and Nicholas Jackson (University of California, San Francisco, United States)
3:15 pm - 3:45 pm
Leonard Zon (Boston Children's Hospital, United States)
"Self-Renewal and Differentiation: Lessons from being a Postdoc to a Professor"
3:45 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Stem Cells and their Niches
Discussion Leaders: Elena Avinery (Ariel University, Israel) and Justine Lengrand (Université Libre de Bruxelles - NETRIS Pharma, Belgium)
5:30 pm - 5:40 pm
Clara Duré (University of Zurich, Switzerland, Switzerland)
"In Vivo Single-Cell Ribosome Profiling to Investigate Translational Regulation in Ageing Epidermal Stem Cells"
5:40 pm - 5:45 pm
Discussion
5:45 pm - 5:55 pm
Maria Azkanaz (Netherlands Cancer Institute , The Netherlands)
"In Vivo Visualization of Stem Cell Dynamics in the Intestine During Homeostasis, Regeneration and Cancer"
5:55 pm - 6:00 pm
Discussion
6:00 pm - 6:10 pm
Buffy Eldridge-Thomas (University of Cambridge, United Kingdom)
"The Transmembrane Proteoglycan Syndecan is Essential for Intestinal Stem Cell Maintenance and Division"
6:10 pm - 6:15 pm
Discussion
6:15 pm - 6:25 pm
Maria Teresa De Angelis (Department of Experimental and Clinical Medicine, University “Magna Graecia”; Catanzaro, Italy., Italy)
"Advanced hiPSC-based 3D Settings to Unravel Fibrotic Programmes in Heart Pathologies"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
Grace Lim (Agency for Science, Technology and Research (A*STAR), Singapore)
"AQP5+ Pyloric Stem Cells Initiate Cancer and Mark a Putative Cancer Stem Cell Pool"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Jana Farhat (Université libre de Bruxelles, Belgium)
"Loss of Kmt2d and Kmt2c Histone Methyltransferases Promotes Tumorigenesis and Displays a Gene Dosage Effect on EMT"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
Sara Hlavca (Monash University, Australia)
"Defining the Role of the Revival Stem Cell during Growth and Therapy Resistance in Colorectal Cancer"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
Micol Baronio (European Institute of Oncology (IEO), Italy)
"Crosstalk Between Tumour Vasculature and Ovarian Cancer Stem Cells: The Role of L1CAM"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Cancer Cells, Microenvironment and Therapeutical Approaches
Discussion Leader: Sylwia Szklarzewska (Université Libre de Bruxelles, Belgium)
9:00 am - 9:10 am
Sara Gallini (Yale university, United States)
"Injury Induces Wild-Type Cell Proliferation to Suppress Oncogenic Ras Cells"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
Katie Teng (LTRI, Mount Sinai Hospital, Canada)
"In Vivo CRISPR Screen to Study Pre-Malignancy in Breast Epithelium at Single-Cell Resolution"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Bartomeu Colom (AltosLabs, United Kingdom)
"Multiple Mutant Clones Contribute to Epithelial Tumour Initiation"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Justine Lengrand (Université Libre de Bruxelles - NETRIS Pharma, Belgium)
"Pharmacological Targeting Netrin-1 Inhibits EMT in Cancer"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Panagiota Tsokkou (Medical University of Vienna, Austria)
"Elucidating the Link Between Psoriasis and Skin Cancer"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Ada Nowosad (VIB-KULeuven, Belgium)
"Dissecting the Cellular and Molecular Interaction Networks that Promote Melanoma Stemness at the Perivascular Niche"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Ryan Boe (University of Pennsylvania, United States)
"Spatial Transcriptomics Reveals Multiple Melanoma Resistant Types in Patients"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Felipe Rodrigues (The Francis Crick Institute, United Kingdom)
"The Lung Metastatic Niche: A Mirror of Cancer Cell Stemness"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Synthetic Biology: Programming Fate and Organization
Discussion Leader: Luis Villa-Diaz ( Oakland University, United States)
1:30 pm - 2:10 pm
Elly Tanaka (IMP, Austria)
"Regeneration and Development, Two Faces of Forming Body Structures"
2:10 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
