| Sunday |
| 4:00 pm - 8:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:40 pm - 9:30 pm | Stochasticity Across Spatial-Temporal Scales |
| Our opening speakers will highlight their research across the main organizing themes of this conference: networks, cells, development and evolution. |
| Discussion Leader: Ken Dill (Stony Brook University, USA) |
| 7:40 pm - 8:10 pm | Hong Qian (University of Washington, USA)
"Foundations for Stochastic Dynamical Descriptions of Living Processes" |
| 8:10 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:45 pm | Marc Kirschner (Harvard Medical School, USA)
"The Origin of Specificity in Regulated Protein Degradation" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:20 pm | Laura Lavine (Washington State University, USA)
"Condition-Dependent Growth and Development of the Exaggerated Weapons of Sexual Selection" |
| 9:20 pm - 9:30 pm | Discussion |
| Monday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Stochasticity in Disease and Cell Fate Networks |
| Discussion Leader: Roy Wollman (University of California, San Diego, USA) |
| 9:00 am - 9:30 am | Jin Wang (Stony Brook University, USA)
"Regulatory Networks Underlying Cancer and Stem Cells" |
| 9:30 am - 9:45 am | Discussion |
| 9:45 am - 10:15 am | Tanja Kortemme (University of California, San Francisco, USA)
"Prediction and Design of Protein-Protein Interactions and Dynamics" |
| 10:15 am - 10:30 am | Discussion |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Hao Li (University of California, San Francisco, USA)
"Physical Principles of Aging, Cancer and Death" |
| 11:30 am - 11:45 am | Discussion |
| 11:45 am - 12:15 pm | Sunney Xie (Harvard University, USA)
"Single-Cell Cancer Genomes" |
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Stochasticity in Signaling Networks |
| Discussion Leader: Leor Weinberger (University of California, San Francisco, USA) |
| 7:30 pm - 7:35 pm | Selected from Poster Abstracts: Alistair Boettiger (Harvard University, USA)
"Super-Resolution Imaging of Chromatin Nano-Structure Reveals Principles of Genome Folding" |
| 7:35 pm - 7:40 pm | Discussion |
| 7:40 pm - 7:45 pm | Selected from Poster Abstracts: Kevin Thurley (University of California, San Francisco, USA)
"Building Population-Level Response Curves from Individual Cell Ca+2 Interspike Intervals" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 7:55 pm | Selected from Poster Abstracts: Maryam Aliee (Ecole Normale Superieure de Lyon, France)
"A Stochastic Model for a Gene Regulatory Network Involved in Plant Morphogenesis" |
| 7:55 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:30 pm | Andre Levchenko (Yale University, USA)
"Noise and Information in Signaling Networks" |
| 8:30 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:15 pm | Long Cai (California Institute of Technology, USA)
"Single Cell Analysis by Sequential FISH" |
| 9:15 pm - 9:30 pm | Discussion |
| Tuesday |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | Stochasticity in Cellular Organization |
| Discussion Leader: Nathalie Balaban (Hebrew University, Israel) |
| 9:00 am - 9:30 am | Daniel Needleman (Harvard University, USA)
"Stochasticity in Spindle Assembly" |
| 9:30 am - 9:45 am | Discussion |
| 9:45 am - 10:15 am | Roy Wollman (University of California, San Diego, USA)
"Accurate Information Transmission Through Dynamic Biochemical Signaling Networks" |
| 10:15 am - 10:30 am | Discussion |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Wallace Marshall (University of California, San Francisco, USA)
"Biological Noise in the Flagellar Length Control System" |
| 11:30 am - 11:45 am | Discussion |
| 11:45 am - 12:15 pm | Alexander Mogilner (New York University, USA)
"Effects of Noise in Actomyosin Contractility" |
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Principles and Consequences of Cellular Heterogeneity |
| Discussion Leader: Vito Quaranta (Vanderbilt University School of Medicine, USA) |
| 7:30 pm - 7:35 pm | Selected from Poster Abstracts: Leonard Harris (Vanderbilt University School of Medicine, USA)
"Intrinsic Stochasticity and Heterogeneous Drug Response in Cancer Cell Populations" |
| 7:35 pm - 7:40 pm | Discussion |
| 7:40 pm - 7:45 pm | Selected from Poster Abstracts: Shicong Xie (Massachusetts Institute of Technology, USA)
"Interactions Between Contractile Events During Tissue Folding" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 7:55 pm | Selected from Poster Abstracts: Franck Raynaud (Ecole Polytechnique Federale de Lausanne, Switzerland)
"Shape-Motion Feedback in Rapidly Migrating Cells" |
| 7:55 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:30 pm | Lani Wu (University of California, San Francisco, USA)
"Heterogeneity of Drug Resistance in Cancer" |
| 8:30 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:15 pm | Nathalie Balaban (Hebrew University, Israel)
"Understanding the Variability of Growth in Single Cells" |
| 9:15 pm - 9:30 pm | Discussion |
| Wednesday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Heterogeneity in Tissue Development and Homeostasis |
| Discussion Leader: Thomas Gregor (Princeton University, USA) |
| 9:00 am - 9:30 am | Leor Weinberger (University of California, San Francisco, USA)
"Harnessing Noise for Therapy" |
| 9:30 am - 9:45 am | Discussion |
| 9:45 am - 10:15 am | Boris Shraiman (Kavli Institute for Theoretical Physics, USA)
"Patterning and Growth in Development" |
| 10:15 am - 10:30 am | Discussion |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Stanislav Shvartsman (Princeton University, USA)
"Modeling Pattern Formation and Morphogenesis" |
| 11:30 am - 11:45 am | Discussion |
| 11:45 am - 12:15 pm | Allon Klein (Harvard Medical School, USA)
"Statistical Physics, Homeostasis and Cancer in Colon Tissue" |
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
| 7:30 pm - 9:30 pm | Stochasticity in Pattern Formation of Developing Tissues |
| Discussion Leader: Zev Gartner (University of California, San Francisco, USA) |
| 7:30 pm - 7:35 pm | Selected from Poster Abstracts: Samuel Skinner (Baylor College of Medicine, USA)
"Single-Cell Analysis of Transcription Kinetics Across the Cell Cycle" |
| 7:35 pm - 7:40 pm | Discussion |
| 7:40 pm - 7:45 pm | Selected from Poster Abstracts: Jacqueline Humphries (University of California, San Diego, USA)
"Population Dynamics Give Rise to Emergent Oscillations in Biofilm Growth" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 7:55 pm | Selected from Poster Abstracts: Orit Peleg (Harvard University, USA)
"Optimal Intermittent Reorientation in Insect Navigation" |
| 7:55 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:30 pm | Claude Desplan (New York University, USA)
"Stochastic vs. Deterministic Choices in the Visual System" |
| 8:30 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:15 pm | Thomas Gregor (Princeton University, USA)
"From Stochastic Transcription to Precise Expression Patterns in the Developing Embryo" |
| 9:15 pm - 9:30 pm | Discussion |
| Thursday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Evolution of Emergent Behaviors in Heterogeneous Cellular Populations |
| Discussion Leader: Daniel Fisher (Stanford Unviersity, USA) |
| 9:00 am - 9:30 am | Gabor Balazsi (Stony Brook University, USA)
"Newcomer Network Evolution: From Non-Genetic to Genetic Drug Resistance and Back Again" |
| 9:30 am - 9:45 am | Discussion |
| 9:45 am - 10:15 am | Peter Robin Hiesinger (University of Texas Southwestern Medical Center, USA)
"Brain Wiring Evolution on the Fly" |
| 10:15 am - 10:30 am | Discussion |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Deborah Gordon (Stanford University, USA)
"The Ecology of Collective Behavior" |
| 11:30 am - 11:45 am | Discussion |
| 11:45 am - 12:15 pm | Oskar Hallatschek (University of California, Berkeley, USA)
"The Role of Noise in the Evolution and Function of Microbial Colonies" |
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Evolutionary Design Principles and Dynamics of Genomes and Proteins |
| Discussion Leader: Marc Kirschner (Harvard Medical School, USA) |
| 7:30 pm - 7:35 pm | Selected from Poster Abstracts: Taraneh Zarin (University of Toronto, Canada)
"Phosphorylation Site Turnover in Disordered Regions: Exploring a Stabilizing Selection Hypothesis" |
| 7:35 pm - 7:40 pm | Discussion |
| 7:40 pm - 7:45 pm | Selected from Poster Abstracts: Lei Dai (Massachusetts Institute of Technology, USA)
"Spatio-Temporal Dynamics Before Population Collapse" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 7:55 pm | Selected from Poster Abstracts: Morgan Delarue (University California, Berkeley, USA)
"A Microfluidic Device
to Confine a Cell Population" |
| 7:55 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:30 pm | Michael Desai (Harvard University, USA)
"Dynamics of Genomic Sequence Evolution in Experimental Populations" |
| 8:30 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:15 pm | Rama Ranganathan (University of Texas Southwestern Medical Center, USA)
"The Evolutionary 'Design' of Proteins" |
| 9:15 pm - 9:30 pm | Discussion |
| Friday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
