Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Stochastic Physics in Molecular and Systems Biology
7:40 pm - 8:10 pm
"Single Cell Genomics, Where Stochasticity Meets Precision"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:45 pm
"The Genetics and Biophysics of Epithelial-Mesenchymal Transition (EMT): Can Theory Help Cancer Biology"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Stochastic Impact of Slow Inhibitors of Translation of Messenger RNAs in the Living Bacterial Cell"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Biomolecular Stochastic Dynamics
9:00 am - 9:30 am
"Stochastic Fluctuation of Cell Sickling from Nucleation of Single Hemoglobin S Fibers"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
"The 3D Genome Architecture and Transcriptional Regulation"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"Molecular Underpinning of Postsynaptic Ca2+ /Calmodulin Signaling, Protein Folding and Conformational Changes In Vivo "
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"Dynamics of Unfolded and Intrinsically Disordered Proteins from Single-Molecule Spectroscopy"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Cell Fate Decision Making
7:30 pm - 8:00 pm
"Trigger Waves in Apoptosis"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Quantifying Stochastic Cell Fate Decision Making"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Correlations and Adaptations Queueing in Enzymatic Networks"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell Growth and Transformations
9:00 am - 9:30 am
"Growth Behavior of Microbes: Monod's Problem Revisited"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
"From the Stochastic Simulation Algorithm to the Small-Voxel Tracking Algorithm"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"Thermodynamics of Biological Systems"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"Neuronal Morphology Driven by Stochastic Branching: Data and Models"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Genomes and Disease Mechanisms
7:30 pm - 8:00 pm
"Effective Detection of Variations in Single Cell Transcriptome"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Cell-Fate Decision Mediated by the P53-Centered Signaling Network"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Towards Predictive Modeling of Three Dimensional Genome Organization"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Interrogating the Robustness of Gene Regulatory Circuits by RACIPE and Cancer Dynamics"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell Structure and Dynamics
9:00 am - 9:30 am
"Stochastic Cell Structures and Dynamics"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
"Stochastic Contributions of Molecular Motors"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"Phase Separation in the Cell Cytoplasm"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"Protein Phase-Separation in and out of Cells"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
7:30 pm - 8:00 pm
"Whole Cell Stochastic Modeling"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Emergent Landscape: Macroscopic Thermodynamics of Mesoscopic, Stochastic Biochemical Kinetics, One Elementary Reaction at a Time"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Mapping Populations onto Phenotypic Planes: Predictive Analysis of Noisy Cellular Decision Making"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:30 am
"Fluctuation-Induced Turing Patterns in Ecology and Biofilms"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
"Building Microbial Communities from the Bottom-Up"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"How Some Cell Behaviors Are Encoded in the Physical Chemistry of the Proteome"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"Real Time Transposable Element Activity in Individual Live Cells"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Cell Dynamics and Functions
7:30 pm - 7:55 pm
"Physics of Information Processing in Biological Systems"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Exact Time-Evolving Probability Landscapes of Stochastic Networks from Chemical Master Equation: Theory, Optimal State Space, and the ACME Algorithm"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"A Self-Enhanced Transport Mechanism Through Long Noncoding RNAs for X Chromosome Inactivation"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"A Structure-Based Mechano-Chemical Model for Microtubule Assembly Dynamics"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Multiple Modes of Quorum Sensing in Streptococcus mutans : Integrating Internal Noise with Environmental Heterogeneity"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Dynamic Criticality Underlies Fidelity of Bacterial Plasmid Segregation"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"A Synthetic Biology Approach to Waddington Landscape and Cell Fate Determination"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure