Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Stochastic Physics in Molecular and Systems Biology
Discussion Leader: Jin Wang (Stony Brook University, USA)
7:40 pm - 8:10 pm
Xiaoliang Sunney Xie (Harvard University & Peking University, USA)
"Single Cell Genomics, Where Stochasticity Meets Precision"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:45 pm
Jose Onuchic (Rice University, USA)
"The Genetics and Biophysics of Epithelial-Mesenchymal Transition (EMT): Can Theory Help Cancer Biology"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
Mans Ehrenberg (Uppsala University, Sweden)
"Stochastic Impact of Slow Inhibitors of Translation of Messenger RNAs in the Living Bacterial Cell"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Biomolecular Stochastic Dynamics
Discussion Leader: Ken Dill (Stony Brook University, USA)
9:00 am - 9:30 am
William Eaton (National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA)
"Stochastic Fluctuation of Cell Sickling from Nucleation of Single Hemoglobin S Fibers"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
Masaki Sasai (Nagoya University, Japan)
"The 3D Genome Architecture and Transcriptional Regulation"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
Margaret Cheung (University of Houston, USA)
"Molecular Underpinning of Postsynaptic Ca2+ /Calmodulin Signaling, Protein Folding and Conformational Changes In Vivo "
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
Benjamin Schuler (University of Zurich, Switzerland)
"Dynamics of Unfolded and Intrinsically Disordered Proteins from Single-Molecule Spectroscopy"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Cell Fate Decision Making
Discussion Leader: Jose Onuchic (Rice University, USA)
7:30 pm - 8:00 pm
James Ferrell (Stanford University, USA)
"Trigger Waves in Apoptosis"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
Jin Wang (Stony Brook University, USA)
"Quantifying Stochastic Cell Fate Decision Making"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
Lev Tsimring (University of California, San Diego, USA)
"Correlations and Adaptations Queueing in Enzymatic Networks"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell Growth and Transformations
Discussion Leader: Xiaoliang Sunney Xie (Harvard University & Peking University, USA)
9:00 am - 9:30 am
Chao Tang (Peking University, China)
"Growth Behavior of Microbes: Monod's Problem Revisited"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
Daniel Gillespie (Dan T. Gillespie Consulting, USA)
"From the Stochastic Simulation Algorithm to the Small-Voxel Tracking Algorithm"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
Qi Ouyang (Beijing University , China)
"Thermodynamics of Biological Systems"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
Jonathon Howard (Yale University, USA)
"Neuronal Morphology Driven by Stochastic Branching: Data and Models"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Genomes and Disease Mechanisms
Discussion Leader: Zan Luthey-Schulten (University of Illinois, USA)
7:30 pm - 8:00 pm
Chenghang Zong (Baylor College of Medicine, USA)
"Effective Detection of Variations in Single Cell Transcriptome"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
Wei Wang (Nanjing University, China)
"Cell-Fate Decision Mediated by the P53-Centered Signaling Network"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Bin Zhang (Massachusetts Institute of Technology, USA)
"Towards Predictive Modeling of Three Dimensional Genome Organization"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Mingyang Lu (Jackson Laboratory, USA)
"Interrogating the Robustness of Gene Regulatory Circuits by RACIPE and Cancer Dynamics"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Steve Presse (Arizona State University, USA)
"Hydrodynamic Hunters"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell Structure and Dynamics
Discussion Leader: Wallace Marshall (University of California, San Francisco, USA)
9:00 am - 9:30 am
Jean-Francois Joanny (ESPCI Paris, France)
"Stochastic Cell Structures and Dynamics"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
David Weitz (Harvard University, USA)
"Stochastic Contributions of Molecular Motors"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
Frank Julicher (Max Planck Institute for the Physics of Complex Systems, Germany)
"Phase Separation in the Cell Cytoplasm"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
Ned Wingreen (Princeton University, USA)
"Protein Phase-Separation in and out of Cells"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Whole Cells
Discussion Leader: Chao Tang (Peking University, China)
7:30 pm - 8:00 pm
Zan Luthey-Schulten (University of Illinois, USA)
"Whole Cell Stochastic Modeling"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
Hong Qian (University of Washington, USA)
"Emergent Landscape: Macroscopic Thermodynamics of Mesoscopic, Stochastic Biochemical Kinetics, One Elementary Reaction at a Time"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
Andre Levchenko (Yale University, USA)
"Mapping Populations onto Phenotypic Planes: Predictive Analysis of Noisy Cellular Decision Making"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Evolution and Ecology
Discussion Leader: Mans Ehrenberg (Uppsala University, Sweden)
9:00 am - 9:30 am
Nigel Goldenfeld (University of Illinois at Urbana-Champaign, USA)
"Fluctuation-Induced Turing Patterns in Ecology and Biofilms"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
Jeff Gore (Massachusetts Institute of Technology, USA)
"Building Microbial Communities from the Bottom-Up"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
Ken Dill (Stony Brook University, USA)
"How Some Cell Behaviors Are Encoded in the Physical Chemistry of the Proteome"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
Thomas Kuhlman (University of Illinois at Urbana-Champaign, USA)
"Real Time Transposable Element Activity in Individual Live Cells"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Cell Dynamics and Functions
Discussion Leader: Nigel Goldenfeld (University of Illinois at Urbana-Champaign, USA)
7:30 pm - 7:55 pm
Yuhai Tu (IBM Thomas J. Watson Research Center, USA)
"Physics of Information Processing in Biological Systems"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Jie Liang (University of Illinois at Chicago, USA)
"Exact Time-Evolving Probability Landscapes of Stochastic Networks from Chemical Master Equation: Theory, Optimal State Space, and the ACME Algorithm"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Chunhe Li (Fudan University, China)
"A Self-Enhanced Transport Mechanism Through Long Noncoding RNAs for X Chromosome Inactivation"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Ao Ma (University of Illinois at Chicago, USA)
"A Structure-Based Mechano-Chemical Model for Microtubule Assembly Dynamics"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Stephen Hagen (University of Florida, USA)
"Multiple Modes of Quorum Sensing in Streptococcus mutans : Integrating Internal Noise with Environmental Heterogeneity"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Jian Liu (NIH, USA)
"Dynamic Criticality Underlies Fidelity of Bacterial Plasmid Segregation"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Xiao Wang (Arizona State University, USA)
"A Synthetic Biology Approach to Waddington Landscape and Cell Fate Determination"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure
