| Sunday, July 8 |
| 2:00-11:00 PM | Arrival & Registration |
| 6:00 PM | Dinner |
| 7:30-9:30 PM | Session 1: Stress Signaling Pathways |
| Steve Keyse, Session Chair |
| 7:30-7:55 PM | Steve Keyse (Dundee)
"Protein phosphatases and the regulation of stress activated signaling" |
| 7:55-8:20 PM | Matthias Gaestel (Martin Luther University)
"Stress signaling downstream to p38: MAPKAP kinases (MKs) as essential components" |
| 8:20-8:35 PM | Coffee Break |
| 8:35-9:00 PM | Ze'ev Ronai (Mt. Sinai)
"JNK/p38 signaling: upstream, downstream and off stream" |
| 9:00-9:25 PM | David Engelberg (Hebrew University)
"Developing constitutively active MAP/Stress kinases - strong tools for analysis of stress responses" |
| 9:30 PM | Wine and Cheese Reception |
| Monday, July 9 |
| 7:30-8:30 AM | Breakfast |
| 9:00AM-12:30PM | Session 2: Biocomplexity and the Organismal Response to Stress |
| Lutz Nover, Session Chair |
| 9:00-9:25 AM | Lutz Nover and Shravan K. Mishra (Goethe University)
"Studies with transgenic tomato: HsfA1 as master regulator for expression of thermotolerance." |
| 9:25-9:50 AM | Steven Triezenberg (Michigan State)
"Transcriptional adaptor proteins and cold-regulated gene expression in Arabidopsis" |
| 9:50-10:15 AM | Martin Feder (University of Chicago)
"How, why, and where evolution may alter cis- and trans- regulation of stress-induced gene expression"
|
| 10:15-10:45 AM | Coffee Break |
| 10:45-11:10 AM | Gordon Lithgow (Manchester, School of Biological Sciences)
"Stress genes as determinates of aging rate" |
| 11:10-11:35 AM | Richard Morimoto (Northwestern University)
"Stressing Worms: Integrating stress pathways in C. elegans" |
| 11:35-noon | Mustafa Khammash (Iowa State University)
"Mathematical Modeling of the heat-shock response in E. Coli" |
| 12:30 PM | Conference Photo |
| After photo-1:30 PM | Lunch |
| 1:30-4:00 PM | Free time |
| 4:30-6:00 PM | Poster Session 1 |
| 6:00 PM | Dinner |
| 7:30-9:30 PM | Session 3: Genotoxicity and Stress on Cell Growth and Oncogenesis |
| Roland Wolf, Session Chair |
| 7:30-7:55 PM | Roland Wolf (Dundee)
"Stress and adaptation to chemical challenge" |
| 7:55-8:20 PM | Ken Tew (Fox Chase Cancer Center)
"Inhibitors of the ligand-binding properties of glutathione S-transferase pi influence cell proliferation pathways" |
| 8:20-8:35 PM | Coffee Break |
| 8:35-9:00 PM | Nikki Holbrook (National Institutes of Aging/NIA)
"Genotoxic/Oxidative Stress Responses: Links to Proliferation and Aging" |
| 9:00-9:15 PM | Ted Hupp (University of Dundee)
"Signal Transduction Pathways Regulating the Tumour
Suppressor p53" |
| Tuesday, July 10 |
| 7:30-8:30 AM | Breakfast |
| 9:00AM-12:30PM | Session 4: Heat Shock and Stress Inducible Transcriptional Control |
| Carol Gross, Session Chair |
| 9:00-9:25 AM | Carol Gross (University of California, San Francisco)
"The Extracytoplasmic Stress Response" |
| 9:25-9:50 AM | Bernd Bukau (University of Freiburg)
"Function and regulation of the E. coli heat shock regulon" |
| 9:50-10:15 AM | Hillary Nelson (University of Pennsylvania)
"Structure, function, and regulation of yeast HSF" |
| 10:15-10:30 AM | Pascal Döring and Kapil Bharti (Goethe University)
"The tomato Hsf network: Protein interactions and synergistic activation of transcription on weak promoters" |
| 10:30-11:00 AM | Coffee Break |
| 11:00-11:25 AM | Dennis Thiele (University of Michigan Medical School)
"Requirements for Differential Responses to Stress by Mammalian Heat Shock Transcription Factors" |
| 11:25-11:50 PM | Akira Nakai (Yamaguchi University School of Medicine)
"Cell cycle transition under stress conditions controlled by vertebrate heat shock factors." |
| 11:50-12:15 PM | John Lis (Cornell University)
"Transcription factor recruitment and function at Drosophila heat shock puffs" |
| 12:30-1:30 PM | Lunch |
| 1:30-3:00 PM | Free Time |
| 3:00-4:00 PM | Poster Session One, Continued |
| 4:30-6:00 PM | Session 5: Short talks from selected abstracts |
| Richard Morimoto, Session Chair |
| 4:30-4:45 PM | Janet Quinn (University of Newcastle)
"Distinct sensors and transcription factors control the adaptive and acute responses to H2O2 in Schizosaccharomyces pombe." |
| 4:45-5:00 PM | Sagadevan G. Mundree (University of Cape Town)
"Isolation and characterization of genes from the resurrection plant xerophyta viscosa baker that are functionally important in conferring tolerance to osmotic stress" |
| 5:00-5:15 PM | D. Scott Merrell (Tufts University School of Medicine)
"Regulation of Acid Induced Genes in Vibrio cholerae" |
| 5:15-5:30 PM | Carina Holmberg (Abo Akademi University)
"Serine Phosphorylation Promotes the Transcriptional Activity of Heat Shock Factor 1" |
| 5:30-5:45 PM | Jane Larkindale (University of Oxford)
"Cell Signalling in response to heat stress in Arabidopsis thaliana" |
| 6:00 PM | Dinner |
| 7:30-9:30 PM | Session 6: Oxidative Stress and Metals |
| Gisela Storz, Session Chair |
| 7:30-7:55 PM | Gisela Storz (NICHD/NIH)
"Overlap between the microbial responses to oxidative stress and metals" |
| 7:55-8:10 PM | Seong-Eon Ryu (Korea)
"Structural mechanism of the cellular redox switch proteins" |
| 8:10-8:35 PM | Bruce Demple (Harvard)
"Transducing free radical signals to defense gene activation" |
| 8:35-8:50 PM | Coffee Break |
| 8:50-9:15 PM | Michel Toledano (CEA/Saclay, Gif-sur-Yvette, France)
"The sensing of hydrogen peroxide and electrophiles by Yap family proteins in yeast" |
| 9:15-9:40 PM | Nic Jones (Manchester)
"Stress-activated transcription in fission yeast" |
| Wednesday, July 11 |
| 7:30-8:30 AM | Breakfast |
| 9:00AM-12:30PM | Session 7: Unfolded Protein Response and Signaling from the ER to the Nucleus |
| Randal Kaufman, Session Chair |
| 9:00-9:25 AM | Randal Kaufman (HHMI/University of Michigan)
"Unfolding the Unfolded Protein Response" |
| 9:25-9:50 AM | Kazu Mori (Kyoto University)
"Membrane-bound transcription factor ATF6 and its targets" |
| 9:50-10:15 AM | Ron Prywes (Columbia University)
"ATF6 as a sensor of the ER stress response." |
| 10:15-10:45 AM | Coffee Break |
| 10:45-11:00 AM | Kenji Kohno (Nara Institute of Science and Technology)
"Various ER-stress responses by ER transmembrane proteins." |
| 11:00-11:25 AM | David Ron (Skirball Institute, NYU School of Medicine)
"Integration of stress induced gene expression by eIF2a kinases" |
| 12:30-1:30 PM | Lunch |
| 1:30-4:00 PM | Free Time |
| 4:30-6:00 PM | Poster Session 2 |
| 6:00 PM | Dinner |
| 7:30-9:30 PM | Session 8: Stress-Induced Post Transcriptional Regulation |
| Nahum Sonenberg (McGill University), Session Chair |
| 7:30-7:55 PM | Nahum Sonenberg (McGill University)
"Control of mRNA recruitment to ribosomes" |
| 7:55-8:20 PM | Christopher Hammell (Dartmouth Medical School)
"Regulation of mRNA export following heat shock in yeast" |
| 8:20-8:45 PM | Robert Schneider (NYU School of Medicine)
"Functional and biochemical characterization of the translation-dependent mRNA decay complex" |
| 8:45-9:00 PM | Coffee Break |
| 9:00-9:25 PM | Paul Anderson (Brigham and Women's Hospital)
"Composition and function of mammalian stress granules" |
| 9:25-9:40 PM | Michal Shapira (Ben Gurion University)
"Developmental regulation of HSP83 in Leishmania: Preferential translation is directed by a determinant in the 3' utr" |
| Thursday, July 12 |
| 7:30-8:30 AM | Breakfast |
| 9:00AM-12:30PM | Session 9: Stress Induced Gene Expression |
| Olivier Bensaude, Session Chair |
| 9:00-9:25 AM | Kazuhiro Shiozaki (University of California, Davis)
"Cellular organization of the stress-responsive MAPK casacde in fission yeast." |
| 9:25-9:50 AM | Haruo Saito (Dana Farber Cancer Institute)
"The HOG osmostress signal transduction pathway in yeast" |
| 9:50-10:15 AM | Olivier Bensaude (Ecole Normale Supérieure)
"The positive transcriptional elongation factor, P-TEFb, is a sensor of transcriptional stress" |
| 10:15-10:40 AM | Qiang Zhou (University of Calfornia, Berkeley)
"A small nuclear RNA switch controls stress-induced HIV-1 transcription". |
| 10:40-11:10 AM | Coffee Break |
| 11:10-11:35 AM | Lorenz Poellinger (Karolinska Institute)
"Regulation of bHLH/PAS transcription function by the hsp90 chaperone complex" |
| 11:35-noon | Kevin Sarge (University of Kentucky)
"Activation of HSF1 by stress-induced SUMO-1 modification" |
| 12:00-12:25 PM | Samson Jacob (Ohio State University)
"Silencing of constitutive and inducible Metallothionein gene expression by promoter methylation in solid tumors in vivo and its molecular mechanisms" |
| 12:30-1:30 PM | Lunch |
| 1:30-4:00 PM | Free Time |
| 4:30-5:30 PM | Poster Session Two, Continued |
| 5:30-6:00 PM | Business Meeting |
| 6:00 PM | Dinner |
| 7:30-9:30 PM | Session 10: Stress in Disease: Inflammation, Bacterial and Viral and Infection |
| Gabriella Santoro, Session Chair |
| 7:30-7:55 PM | Gabriella Santoro (University of Rome)
"Activation of the stress response by viral infection" |
| 7:55-8:20 PM | Peter Csermely (BioRex R&D Co.)
"Chaperone co-inducers: A novel class of pharmaceuticals with a simultaneous membrane modulation and induction of the heat shock response." |
| 8:20-8:35 PM | Coffee Break |
| 8:35-9:00 PM | Walter Schaffner (University of Zurich-Irchel)
"Heavy metal-responsive gene transcription in mammals and insects" |
| 9:00-9:25 PM | Hermona Soreq (The Hebrew University of Jerusalem)
"Acetylcholinesterase as a window to stress responses" |
| Friday , July 13 |
| 7:30-8:30 AM | Breakfast and Departure |
