| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | STRESS INDUCED SIGNALLING PATHWAYS |
| Discussion Leader: Nic Jones |
| 7:30 pm - 7:55 pm | Francesc Posas (Barcelona, Spain)
Osmostress Responses Under the Control of the Hog1 MAP Kinase |
| 7:55 pm - 8:20 pm | Kazuhiro Shiozaki (University of California,
Davis, USA)
Regulators of Spc1 SAPK in Fission Yeast |
| 8:20 pm - 8:45 pm | Steve Keyse (Cancer Research UK, Dundee)
Physiological Roles for Dual-Specificity Protein Phosphatases in Regulating the Outcome of MAP Kinase Signalling
|
| 8:45 pm - 9:10 pm | Roger Davies (University of Massachusetts
Medical School, USA)
Signal Transduction by Stress-Activated MAP Kinases |
| WINE AND CHEESE RECEPTION |
| MONDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | STRESS RESPONSES IN PLANTS/YEAST |
| Discussion Leader: Lutz Nover |
| 9:00 am - 9:25 am | Mike Thomashow (Michigan State University,
USA)
Regulatory Genes and Regulons Involved in Plant Freezing Tolerance |
| 9:25 am - 9:50 am | Julia Bailey-Serres (University of California, USA)
Initiation and Regulation of Rop GTPase Signaling in Response to Oxygen Deprivation in Arabidopsis |
| 9:50 am - 10:15 am | David Hubert (University of North Carolina, USA)
Specific Recognition of Pathogens by Plants |
| 10:15 am - 10:45 am | Coffee Break |
| 10:45 am - 11:10 am | Pascal von Koskull-Doring and Shravan Mishra (Frankfurt, Germany)
Deciphering the Complexity of the Plant hs Response Using RNAi Technology |
| 11:10 am - 11:35 am | Miguel Rodriguez (The Scripps Research Institute, USA)
The RNA Binding Protein Csx1 Mediates Global Control of Gene Expression in Response to Oxidative Stress |
| 12:45 pm | Group Photo / Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | UNFOLDED PROTEIN RESPONSE |
| Discussion Leader: David Ron |
| 7:30 pm - 7:55 pm | David Ron (Skirball Institute, USA)
Cellular Adaptations to the Metabolic Demands of Secretory Protein Biosynthesis |
| 7:55 pm - 8:20 pm | Kazu Mori (Kyoto University, Japan)
Roles of Transcriptional Induction Programs in the Quality Control System in the Endoplasmic Reticulum |
| 8:20 pm - 8:45 pm | Peter Walter (University of California, USA)
Regulation of the Unfolded Protein Response: From Linear Pathway to Signaling Network |
| 8:45 pm - 9:10 pm | Brian Freeman (University of Illinois, USA)
Genomic Localization and Effects of the P23 and HSP90 Molecular Chaperones |
| TUESDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | HEAT SHOCK |
| Discussion Leader: Rick Morimoto |
| 9:00 am - 9:25 am | Carol Gross (University of California, USA)
How a Protease Cascade Functions as a Signal Transduction System |
| 9:25 am - 9:50 am | Susan Lindquist (Whitehead Institute, USA)
Heat Shock Proteins and Prion Conformation Switches |
| 9:50 am - 10:15 am | Rick Morimoto (Northwestern University, USA)
Role of Hsf1 and Chaperone Networks in Protein Homeostasis and Aging |
| 10:15 am - 10:45 am | Coffee Break |
| 10:45 am - 11:10 am | Lea Sistonen(Abo Akademi University, Finland)
Regulation of HSF1 by Post-translational Modifications |
| 11:10 am - 11:35 am | Denis Thiele (University of Michigan Medical
School, USA)
Stress Regulation of the Heat Shock Response in Yeast and Mammals |
| 11:35 am - 12:00 pm | Kevin Moreno (University of Texas Medical School, USA)
New Roles for the Sse1p Molecular Chaperone in Signal Transduction |
| 12:00 pm - 12:25 pm | John Lis (Cornell University, USA)
Dissecting the Mechanics of Heat Shock Gene Activation In Vivo |
| 12:30 pm | Lunch |
| 1:30 pm - 6:00 pm | Free Time |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | STRESS INDUCED CHANGES IN GENE EXPRESSION |
| Discussion Leader: Michel Toledano |
| 7:30 pm - 7:55 pm | Audrey Gasch (University of California, USA)
The Role, Regulation and Evolution of the Environmental Stress Response in Yeast |
| 7:55 pm - 8:20 pm | Nic Jones (Manchester, UK)
Stress-induced Transcription in S. Pombe |
| 8:20 pm - 8:45 pm | Jean Labarre (CEA/Saclay, France)
Analysis of Stress Induced Changes in Gene Expression Reveals Structural Constraints on Messagers and Proteins |
| 8:45 pm - 9:10 pm | Dirk Bohmann (University of Rochester, USA)
Stress Signaling by the Drosophila JNK Pathway |
| WEDNESDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | OXIDATIVE STRESS AND METALS |
| Discussion Leader: Denis Thiele |
| 9:00 am - 9:25 am | Bruce Demple (Harvard, USA)
Sensing and Combatting Toxic Free Radicals |
| 9:25 am - 9:50 am | Jonathan Freedman (Duke University, USA)
Oxidative Stress as a Mediator of Copper-Responsive Signal Transduction Pathways |
| 9:50 am - 10:15 am | Michel Toledano (CEA/Saclay, France)
H202 Sensing and Homeostasis in Yeast |
| 10:15 am - 10:45 am | Coffee Break |
| 10:45 am - 11:10 am | Shusuke Kuge (Sendai, Japan)
Redox Shift-Mediated Oxidative Stress Sensing by Two Step Thiol-Disulfide Exchanging Reactions of Yap1 Transcription Factor
|
| 11:10 am - 11:35 am | Yuko Yamaguchi-Iwai (Kyoto University, Japan)
Iron-mediated Transcriptional Control by Aft1p, an Iron-responsive Transcriptional Activator in S. cerevisiae |
| 11:35 am - 12:00 pm | Walter Schaffner (University of Zurich, Switzerland)
Heavy Metal Stress Response from Insects to Mammals |
| 12:00 pm - 12:25 pm | Norma Masson (Oxford University, UK)
Regulation of Hypoxia-Inducible Factor (HIF) by Oxygen-Dependent Protein Hydroxylation |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | SHORT TALKS FROM SELECTED ABSTRACTS |
| Discussion Leader: TBA |
| 7:30 pm - 7:50 pm | Janet Quinn
The Fission Yeast Sty1 SAPK Pathway - From the Top to the Bottom |
| 7:50 pm - 8:10 pm | Elena Hidalgo (Universitat Pompeu Fabra, Spain)
Regulating the Cellular Localization of the Redox Sensor Pap1 |
| 8:10 pm - 8:30 pm | Ruth Bancewitz (Medical Research Council, UK)
Hsp90 as a Buffer of Developmental Defects in Vertebrates |
| 8:30 pm - 8:50 pm | Sandy Westerheide (Northwestern University, USA)
Small Molecule Modulators of the Heat Shock Response |
| 8:50 pm - 9:10 pm | John Murray (Stanford University, USA)
Diverse and Specific Gene Expression Responses to Stresses in Human Cell Lines |
| THURSDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | GENOTOXICITY AND STRESS ON CELL GROWTH AND DEATH |
| Discussion Leader: Roger Davis |
| 9:00 am - 9:25 am | Jonathan Millar (National Institute for Medical Research, UK)
Mitotic Stress Checkpoints in Fission Yeast |
| 9:25 am - 9:50 am | Rosa Aligue (University of Barcelona, Spain)
A New Kinase Family Involved in Stress Response in Fission Yeast |
| 9:50 am - 10:15 am | Dmitry Bulavin (NIH, USA)
The p38 MAPK/Wip1 Signaling Pathway and Tumorigenesis |
| 10:15 am - 10:45 am | Coffee Break |
| 10:45 am - 11:10 am | Gawain McColl (Buck Institute, USA) |
| 11:10 am - 11:35 am | Roland Wolf (Cancer Research UK, Dundee)
Interplay Between Genes Regulated by Oxidative Stress and Those Associated with Chemical Detoxification |
| 11:35 am - 12:00 pm | Ze'ev Ronai (Mount Sinai School of Medicine, USA)
A Ubiquitin Twist in TRAF2 Signaling |
| 12:00 pm - 12:25 pm | Jeremy Blaydes (University of Southampton, UK)
Regulation of p53 Function by Hypoxic Stress: A Novel Role for CtBP Transcriptional Repressors |
| 12:30 pm | Lunch |
| 1:30 pm - 6:00 pm | Free Time |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | STRESS IN DISEASE |
| Discussion Leader: Walter Schaffner |
| 7:30 pm - 7:55 pm | Axel Behrens (Cancer Research UK)
Interpretation of JNK Signalling by Proteins Interacting with N-terminally Phosphorylated c-Jun |
| 7:55 pm - 8:20 pm | Peter Csermely (BioRex, Hungary)
Chaperone Co-inducers: Novel HSF-interacting Drugs |
| 8:20 pm - 8:45 pm | Ivor Benjamin (University of Texas, USA)
Molecular Chaperones (HSP) and the Control of Mitochondrial Permeability Transition and ROS Production |
| 8:45 pm - 9:10 pm | Junjii Yodoi (Kyoto University, Japan)
Tumour Suppression by TBP-2/VDUP1, A Negative Regulator of Thioredoxin (TRX) |
| FRIDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
