SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 8:30 pm | Meeting Opening Session |
7:30 pm | Dennis J. Thiele and Peter Walter Introduction |
7:45 pm | Keynote Address: Elizabeth Craig (University of Wisconsin-Madison)
"Hsp70 molecular chaperones: beyond protein folding" |
8:30 pm - 9:30 pm | Proteotoxicity |
| Discussion leader: Elizabeth Craig |
8:30 pm | Bernd Bukau (Univ. Heidelberg, Germany)
"Mechanisms of bacterial chaperones" |
9:00 pm | Carol Gross (UC-San Francisco)
"Diversification and adaptation of bacterial stress responses" |
9:30 pm | Reception |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Stress in cellular compartments |
| Discussion leader: David Ron |
9:00 am | David Ron (New York University)
"Compartment-specific adaptation to protein misfolding" |
9:30 am | Jonathan Weissman (UC-San Francisco)
"Sensing and responding to protein misfolding in the endoplasmic reticulum" |
10:00 am | Break / Conference Photo (10:15 am) |
10:45 am | Martin Duennwald (MIT)
"The induction of ER stress as a source for polyglutamine toxicity" |
11:00 am | Richard Gardner (Fred Hutchinson Cancer Institute)
"Protein quality control degradation in the nucleus" |
11:15 am | Jason Brickner (UC-San Francisco)
"How the ER lumen talks to the nucleus" |
11:45 am | Niwa Maho (UC-San Diego)
"Role of the unfolded protein response during hematopoietic stem cell development" |
12:00 pm | Amada McBroom (Duke University)
"Outer membrane vesiculation is an envelope stress response mechanism in Escherichia coli" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Stress signals in transcriptional activation |
| Discussion leader: Lea Sistonen |
7:30 pm | Lea Sistonen (Abo Academy, Turku, Finland)
"Regulation of mammalian HSFs by SUMOlylation" |
8:00 pm | Akira Nakai (Yamaguchi Medical School, Japan)
"Roles of HSFs during development of placode-derived sensory organs" |
8:30 pm | Xinnian Dong (Duke University)
"Regulation of defense-related proteins during systemic acquired resistance in Arabidopsis" |
9:00 pm | Amy Trott (Univ. Texas Medical Center, Houston)
"Combinatorial control of Msn2 stability and function by protein kinase A and the Hsp90 chaperone complex" |
9:15 pm | Eric Guisbert (Univ. California-San Francisco)
"A chaperone network regulates the heat shock response in E. coli" |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Mechanisms of stress regulation |
| Discussion leader: Caroline Jolly |
9:00 am | John Lis (Cornell University)
"Dissecting mechanisms of transcription and its regulation in vivo" |
9:30 am | Caroline Jolly (University Grenoble)
"HSF1 and chromatin remodeling during heat shock" |
10:00 am | Break |
10:30 am | Sandy Westerheide (Northwestern University)
"The role of acetylation on the Hsp70 Promoter" |
10:45 am | Kevin Sarge (Univ. of Kentucky)
"Mechanism, regulation and function of bookmarking of stress genes" |
11:00 am | Johanna Ahlskog (Abo Academy, Turku, Finland)
"HSF1 affects the stability of HSF2 and its binding to the hsp70 promoter" |
11:15 am | Evgeny Nudler (New York Univ.)
"RNA-mediated response to heat shock in mammalian cells" |
11:30 am | Richard Morimoto (Northwestern University)
"Genome-wide screen for novel regulators of the C. elegans heat shock response" |
12:00 pm | James Goodrich (University of Colorado)
"Regulation of mammalian transcription by non-coding RNA during heat shock |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Stress, Cell Survival and Death |
| Discussion leader: Helen Beere |
7:30 pm | Helen Beere (La Jolla Institute for Allergy and Immunology)
"Functional interaction between the stress response and the regulation of apoptosis" |
8:00 pm | Cam Patterson (Univ. North Carolina-Chapel Hill)
"Coordination of protein quality control, cell survival and the stress response" |
8:30 pm | Kevin Morano (Univ. Texas Medical Center, Houston)
"Roles of the Hsp110 chaperone in budding yeast" |
9:00 pm | Luke Whitsell (Univ. Arizona)
"A role for the stress response in cancer evolution" |
9:15 pm | Ji-Sook Hahn (Seoul National University, Korea)
"Regulation of Nod1-mediated innate immune response by Hsp90 chaperone complex" |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Cell Biology of Stress |
| Discussion leader: Ron Kopito |
9:00 am | Ron Kopito (Stanford University)
"Cellular strategies for aggregate suppression" |
9:30 am | Tso-Pang Yao (Duke University Medical Center)
"Regulation of the molecular chaperone Hsp90 by reversible protein acetylation" |
10:00 am | Break |
10:30 am - 12:30 pm | Aging-Stress Axis |
| Discussion leader: Cynthia Kenyon |
10:30 am | Cynthia Kenyon (Univ. California-San Francisco)
"Stress proteins in disease and aging in C. elegans" |
11:15 am | Lenny Guarente (MIT)
"Sir2p and calorie restriction" |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Oxidative Stress |
| Discussion leader: Michel Toledano |
7:30 pm | Michel Toledano (University of Saclay, France)
"H2O2 signaling through cysteine redox modifications" |
8:00 pm | Elizabeth Veal (Univ. of Newcastle upon Tyne)
"2-Cys peroxiredoxins in peroxide-signaling and the response to oxidative stress" |
8:15 pm | Claudina Rodrigues-Pousada (Instituto de Tecnologia Química e Biológica, Portugal)
"Yap1 and Yap8 are involved in the response to the metalloid arsenic" |
8:30 pm | Keith Blackwell (Joslin Diabetes Center, Harvard)
"Regulation of C. elegans oxidative stress defense protein SKN-1 by GSK-3 and insulin-like signaling" |
8:45 pm | Yasuomi Tada (Duke University)
"Cellular Redox Changes Control Plant Systemic Acquired Resistance" |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Stress Proteins in Normal Biology and in Disease |
| Discussion leader: Susan Lindquist |
9:00 am | Susan Lindquist (MIT)
"Self Perpetuating Protein Conformations in Biology and Disease" |
9:30 am | Liming Li (Northwestern Univ.)
"Role of HSF in protein aggregation and yeast prion formation" |
10:00 am | Break |
10:30 am | Mitsuaki Fujimoto (Yamaguchi University)
"Overexpression of an active HSF1 in non-neural tissues improves the lifespan of Huntington's Disease mice" |
10:45 am | Valerie Mezger (Ecole Normale Superieure, Paris)
"HSF2 involvment in brain cortical development" |
11:00 am | Lisa Cunningham (Medical University of South Carolina)
"Heat Shock-Induced Inhibition of Sensory Hair Cell Death in the Inner Ear" |
11:15 am | Zhonghua Liu (Kansas State University)
"AAA+ ATPase TorsinA Directly Interacts with a Nuclear-Envelope Protein LAP1B" |
11:30 am | Business Meeting: Plans for the 2007 Meeting |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Stress Proteins and Disease |
| Discussion Leader: Ivor Benjamin |
7:30 pm | Ivor Benjamin (Univ. Utah Medical Center)
"Reductive stress on protein aggregation in desmin-related diseases" |
8:00 pm | Jeffrey Robbins (Childrens Hospital Res. Foundation, Cincinnati)
"The heat shock proteins and heart failure: an unfolding story" |
8:30 pm | Jeffrey Brodsky (Univ. Pittsburgh)
"Co-opting stress responses in yeast to identify genetic modifiers of human disease" |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |