Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Environmental Synthetic Biology
Discussion Leader: Andrew Ellington (University of Texas at Austin, USA)
7:40 pm - 8:20 pm
Sven Panke (ETH Zurich, Switzerland)
"From Evolving to Designing Function"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
James Collins (Massachusetts Institute of Technology, USA)
"Synthetic Biology for Global Health"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Exotic Molecules and Materials
Discussion Leader: Jean Marie Francois (University Federal of Toulouse, France)
9:00 am - 9:30 am
Nico Callewaert (VIB, Ghent University, Belgium)
"Reconstructing and Deconstructing Biopharmaceutical Glycosylation"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
Michelle Chang (University of California, Berkeley, USA)
"Metabolic Engineering Approaches to Bioorthogonal Chemistry"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
Mary Dunlop (Boston University, USA)
"Engineering and Optimizing Biofuel-Tolerant Microbes"
11:30 am - 11:45 am
Discussion
11:45 am - 11:55 am
Shiva Razavi (Johns Hopkins University School of Medicine, USA)
"Bottom-Up Engineering of Chemotaxis in Artificial Cells"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
Organizers: Michelle Chang (University of California, Berkeley, USA) and Pamela Silver (Harvard University, USA)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Biological Design, Automation and Computation
Discussion Leader: Paul Freemont (Imperial College London, United Kingdom)
7:30 pm - 8:10 pm
Chang Liu (University of California, Irvine, USA)
"Orthogonal Replication for Rapid Mutation and Synthetic Biology"
8:10 pm - 8:30 pm
Discussion
8:30 pm - 9:10 pm
Christopher Voigt (Massachusetts Institute of Technology, USA)
"Design in Synthetic Biology"
9:10 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Mammalian Synthetic Biology
Discussion Leader: Tara Deans (University of Utah, USA)
9:00 am - 9:30 am
Brian Chow (University of Pennsylvania, USA)
"Mammalian Cell-Expressible De Novo Fluorescent Proteins"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
Yvonne Chen (University of California, Los Angeles, USA)
"Engineering Smarter and Stronger T Cells for Cancer Immunotherapy"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
Jesse Rinehart (Yale School of Medicine, USA)
"Encoding the Human Serine Phosphoproteome in an Engineered Bacterial System"
11:30 am - 11:45 am
Discussion
11:45 am - 11:55 am
Vanessa Restrepo Schild (University of Oxford, United Kingdom)
"Reconstructing Vision from the Bottom Up"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Engineering Microbial Communities
Discussion Leader: Daniela Quaglia (Universite de Montreal, Canada)
7:30 pm - 8:10 pm
Pamela Silver (Harvard University, USA)
"Re-Programming the Gut Microbiome"
8:10 pm - 8:30 pm
Discussion
8:30 pm - 9:10 pm
Filipe Cabreiro (University College London, United Kingdom)
"Re-Programming Bacterial Metabolism for Cancer Therapy"
9:10 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Enabling Technologies
Discussion Leader: Vitor Martins Dos Santos (Wageningen University & Research, The Netherlands)
9:00 am - 9:40 am
Ahmad Khalil (Boston University / Wyss Institute, Harvard University, USA)
"Epigenetics and Evolution in the Age of Synthetic Biology"
9:40 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:10 am
Alanna Schepartz (Yale University, USA)
"Visualizing Organelle Dynamics for (Almost) Forever at Super-Resolution"
11:10 am - 11:30 am
Discussion
11:30 am - 11:50 am
Scott Boyken (University of Washington, USA)
"De Novo Design of Protein Logic via Hydrogen Bond Network-Mediated Specificity: New Tools to Engineer Cellular Signaling"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Industrial Applications of Synthetic Biology
Discussion Leader: Ann Marie Faust (Novartis Institutes for BioMedical Research, USA)
7:30 pm - 7:50 pm
Emily Leproust (Twist Bioscience, USA)
"The Synthetic DNA Engine for the Bioeconomy"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Barry Canton (Ginkgo Bioworks, USA)
"Building Scale and Flexibility at the Ginkgo Bioworks Foundry"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Matthew Weinstock (Synthetic Genomics, USA)
"The Development of Novel Host Organisms for the Biotech Industry"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Paul Miller (Synlogic, USA)
"Engineering Bacteria as Living Therapeutics"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Biological Circuits
Discussion Leader: Karen Polizzi (Imperial College London, United Kingdom)
9:00 am - 9:30 am
Tae Seok Moon (Washington University in St. Louis, USA)
"Developing Complex, Environmentally-Responsive Genetic Circuits for Real-World Applications"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
Peter Carr (Massachusetts Institute of Technology, USA)
"Test-Driving New Genetic Codes: In Silico , to In Vitro , to In Vivo "
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
Abhishek Chatterjee (Boston College, USA)
"Development and Applications of Universal Platforms for Genetic Code Expansion"
11:30 am - 11:45 am
Discussion
11:45 am - 11:55 am
Yorke Zhang (The Scripps Research Institute, USA)
"A Semi-Synthetic Organism with an Expanded Genetic Code"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Designing and Writing Genomes
Discussion Leaders: Marc Lajoie (University of Washington, USA) and Antje Kruger (University College London, United Kingdom)
7:30 pm - 8:10 pm
Leslie Mitchell (New York University Medical Center, USA)
"Designing and Building Synthetic Eukaryotic Chromosomes and Genomes"
8:10 pm - 8:30 pm
Discussion
8:30 pm - 9:10 pm
Kevin Esvelt (Massachusetts Institute of Technology, USA)
"Daisy Drive Systems for Local and Community-Directed Ecological Engineering"
9:10 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure