SATURDAY |
1:30 pm - 4:30 pm | Arrival and Check-in |
3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:15 pm - 4:00 pm | Characterization of Protein Response to Oxidation |
| Discussion Leader: Nelmi Devarie Baez (Wake Forest University School of Medicine) |
3:15 pm - 3:27 pm | Holly Bryan (University of Liverpool)
"The Chemical Mechanism of Action of CDDO-Me - A Potent Inducer of the Nrf2 Cell Defense Pathway"
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3:27 pm - 3:30 pm | Discussion |
3:30 pm - 3:42 pm | Zhenbo Cao (Univeristy of Glasgow)
"Lack of an Efficient Endoplasmic Reticulum-Localized Recycling System Protects Peroxiredoxin IV from Hyperoxidation"
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3:42 pm - 3:45 pm | Discussion |
3:45 pm - 3:57 pm | Ari Zeida (University of Buenos Aires)
"Molecular Basis of Thiol Oxidation by Peroxides: Aqueous Solution and Peroxiredoxins"
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3:57 pm - 4:00 pm | Discussion |
4:00 pm - 5:30 pm | Poster Session I |
5:30 pm - 7:30 pm | Protein Response to Oxidation and Nitration |
| Discussion Leaders: Esther Jortzik (Justus Liebig University Giess) and Mirko Sobotta (German Cancer Research Center)
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5:30 pm - 5:45 pm | Laura Botello-Morte (University of Zaragoza)
"Disulfide Reductase Activity and Redox Properties of the Global Regulator FurA: A Novel CXXC-Based Redox Sensor?"
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5:45 pm - 5:50 pm | Discussion |
5:50 pm - 6:05 pm | Brandan Pedre Perez (Vrije Universiteit Brussel)
"A Peroxidase of Corynebacterium glutamicum Shows Promiscuity in Thiol Redox Regulation"
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6:05 pm - 6:10 pm | Discussion |
6:10 pm - 6:25 pm | Jeremiah Keyes (Wake Forest University School of Medicine)
"Modulation of Erk Activity by Reversible Cysteine Oxidation"
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6:25 pm - 6:30 pm | Discussion |
6:30 pm - 6:45 pm | Deepthi Menon (Australian National University)
"Redox Modifications of Proteins: Glutathione Transferase Omega 1 (GSTO1-1) as a Deglutathionylase"
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6:45 pm - 6:50 pm | Discussion |
6:50 pm - 7:05 pm | Lewis Tomalin (Newcastle University)
"A Kinetic Modeling Approach to Aid Our Understanding of Intracellular H2O2 Dynamics and Peroxiredoxin Hyperoxidation"
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7:05 pm - 7:10 pm | Discussion |
7:10 pm - 7:25 pm | Marcel Van Lith (University of Glasgow)
"Monitoring Cellular Redox Status During Metabolic Changes Using Redox-Sensitive GFPs"
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7:25 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Role of Environmental and Cellular Oxidants in Signaling and Disease |
| Discussion Leaders: Julie Reisz (Wake Forest University School of Medicine) and Jun Liu (University of Delaware)
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9:00 am - 9:15 am | Jesalyn Bolduc (Wake Forest University School of Medicine)
"Determining the Molecular Basis for Human Prx1 and Prx2 Differential Susceptibility to Hyperoxidation and Inactivation"
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9:15 am - 9:20 am | Discussion |
9:20 am - 9:35 am | Mickael Briens (Institut de Biologie Moleculaire)
"Role of the Selenoprotein N in Redox Signaling Networks"
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9:35 am - 9:40 am | Discussion |
9:40 am - 9:55 am | Jade Mims (Wake Forest School of Medicine)
"Integrated Model for Radiation Induced Redox Signaling in Head and Neck Squamous Cell Carcinoma"
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9:55 am - 10:00 am | Discussion |
10:00 am - 10:15 am | Edward Chouchani (University of Cambridge)
"S-Nitrosation of a Cysteine Switch on Mitochondrial Complex I Protects from Acute Ischemia/Reperfusion Damage and Post Myocardial Infarction Heart Failure"
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10:15 am - 10:20 am | Discussion |
10:20 am - 10:35 am | Ana Gomes Barata (German Cancer Research Center)
"H2O2 in Mitochondrial Function and Homeostasis"
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10:35 am - 10:40 am | Discussion |
10:30 am - 10:50 am | Marieke Visscher (Universitair Medisch Centrum)
"Redox Regulation of the Tumor Suppressor p16"
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10:50 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Developing Your Scientific Career |
| Discussion Leader: Inge Van Molle (VIB Structural Biology Research Center) |
1:30 pm - 1:35 pm | Panelist Introductions: Toren Finkel (National Institutes of Health), Michel Toledano (CEA, IBITECS, LSOC), and Elizabeth Veal (Newcastle University) |
1:35 pm - 2:30 pm | Open Mentor Panel Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |