Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Novel Factors in Thiol Biochemistry
3:15 pm - 3:25 pm
"Catalysis of the Reaction Between Nitroconjugated Linoleic acid and Glutathione by Human Glutathione Transferases"
3:25 pm - 3:30 pm
Discussion
3:30 pm - 3:40 pm
"Functional Asymmetry and Chemical Reactivity of CsoR Family Persulfide Sensors"
3:40 pm - 3:45 pm
Discussion
3:45 pm - 3:55 pm
"Activation of the Calcium/Calmodulin Dependent Kinase II (CaMKII) by Disulfide Formation"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Thiol-Redox Elements in Health and Disease
5:30 pm - 5:45 pm
"Cysteine depletion-induced ferroptosis in drug resistant glioblastoma"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
"Reprogramming of hydrogen sulfide metabolism can support targeted therapy resistance in melanoma"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
"S-Glutathionylation and S-Nitrosylation in Spinal Muscular Atrophy"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
"Redox Regulation of Tissue Regeneration and the Injury Response"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
"Thiol-peroxidase AhpC1 Confers Pseudomonas aeruginosa Pathogenicity Through Reduction of Oxidants Generated During Inflammation"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
"TGF-ß vs Nrf2; Redox Signalling in Liver Fibrosis"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Tools to Monitor Thiol-Redox Modifications
9:00 am - 9:15 am
"Revisiting SSP4: a Comprehensive Analysis into the Fluorescent Probe and its Applications in Biological Systems for the Detection of Sulfane Sulfurs"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"Critical Re-investigations of Alkylation Reactions in Relation to the Detection of Per- and Polysulfide Species"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
"The Role of Glutathione in the Periplasm of Escherichia coli"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
"How to Kill with Gold? Elucidating Auranofin's (AF) Mechanism of Action in Bacterial Cells"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
"Differential Receptor-Dependent Hydrogen Peroxide Signaling via Nox Isoforms in Vascular Endothelial Cells: Critical Roles for Rac1 and Modulation by Statins"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
"DPANzine – a Novel Fluorescent Reporter for Protein Carbonylation"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Navigating Your Scientific Career Path
1:30 pm - 2:30 pm
Panel Discussion
Navigating Your Scientific Career Path
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes