Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
3:15 pm - 3:25 pm
"Human Glutathione Transferases Catalyze the Inactivation of Nitrooleic Acid"
3:25 pm - 3:30 pm
Discussion
3:30 pm - 3:40 pm
"2H-Thiopyran-2-Thione Sulfine and its Analogues: Unique Compounds For Converting H2S to HSOH/H2S2"
3:40 pm - 3:45 pm
Discussion
3:45 pm - 3:55 pm
"Effect of p-Benzoquinone, a Cigarette Smoke-Derived Component, on the Architecture of Red Blood Cell Membrane"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Cellular Redox Signaling and Regulation
5:30 pm - 5:40 pm
"Precision Persulfide Generation Provides Insight into the Mitochondrial Sulfane Sulfur Pool"
5:40 pm - 5:45 pm
Discussion
5:45 pm - 5:55 pm
"Thiol Based Defense Mechanisms of Mycobacterium Tuberculosis Against Hypochlorous Acid"
5:55 pm - 6:00 pm
Discussion
6:00 pm - 6:10 pm
"Exploring Skeletal Muscle Cysteine Oxidation Shifts Immediately Post and in Recovery from Acute Exercise"
6:10 pm - 6:15 pm
Discussion
6:15 pm - 6:25 pm
"Active Site Cysteine Positioning in a Trypanosoma Brucei Dual-Function Peroxiredoxin Enables Adaptation to a Parasitic Life Style"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"A 2-Cys Peroxiredoxin Confers Redox Sensitivity on a p38-Related MAPK by Dual Independent Mechanisms"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
"Mediator Complex Subunit 16 (MED16): Its Physiological Role and Redox-dependent Regulations"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
"Novel Modification of Peroxiredoxin 3 After Mitochondrial Oxidative Stress"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"A New Role for Cu/Zn Superoxide Dismutase in Fe/S Biogenesis"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Tools to Monitor Thiol-Redox Modifications
9:00 am - 9:10 am
"Exploring Endogenous Modulators of Protein Persulfidation Using a Novel Quantitative Assay"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"Deciphering Subcellular Redox Dynamics in AML: Insights from Genetically Encoded Sensors and Live-Cell Imaging"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"An Approach to the Study of Single Cell Redox Dynamics by Using Cancer Patient-Derived Organoids (PDOs) and Compartment-Specific Genetically-Encoded Redox Biosensors"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"An Electrochemical Method to Switch, Monitor, and Control Mucus Thiol-Disulfide in a Gut Model System"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Understanding the Architecture of Human Redox-Relay Complexes"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"The Anticancer Compounds Auranofin, TRi-1 and TRi-2 have Distinct Cytotoxicity Profiles with Regards to Thioredoxin Reductase Inhibition"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Exploring the Implications of a Novel Silver-Ruthenium-Based Surface Coating on the Bacterial Redox Homeostasis"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
"Inter-Compartmental H2 O2 Fluxes and their Regulation by Scavengers, Transporters and Signaling Cascades Affect Cell Fitness"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Navigating Your Career Path: How to Make Science More Inclusive
1:30 pm - 2:30 pm
Panel Discussion
Navigating Your Scientific Career Path
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
