| Sunday, June 24 |
| 2:00 p.m. - 11:00 p.m. | Arrival & Registration |
| 6:00 p.m. - 7:30 p.m. | Dinner |
| 7:30 p.m. - 9:45 p.m. | Theme: High Throughput at High Resolution |
| (Discussion Leader: Robert Glaeser) |
| 7:30 p.m. - 7:45 p.m. | WELCOME & CONFERENCE INTRODUCTION |
| 7:45 p.m. - 8:45 p.m. | Joachim Frank, (Albany, NY):
MULTIPLE CONFORMATIONAL STATES OF THE RIBOSOME |
| 8:45 p.m. - 9:45 p.m. | Yoshinori Fujiyoshi (Kyoto):
2-D CRYSTALS OF MEMBRANE PROTEINS |
| Monday, June 25 |
| 7:30 a.m. - 8:30 a.m. | Breakfast |
| 8:30 a.m. - 9:00 a.m. | Conference Photo |
| 9:00 a.m. - 12:20 p.m. | Theme: High Throughput with Single Particles |
| (Discussion Leader: Helen Saibil; London ) |
| 9:00 a.m. - 9:10 a.m. | INTRODUCTION AND OVERVIEW |
| 9:10 a.m. - 9:50 a.m. | Phoebe Stewart (UCLA)
ASYMMETRIC TO ICOSAHEDRAL SINGLE PARTICLES |
| 9:50 a.m. - 10:30 a.m. | Neil Ranson (London)
GLOBAL REARRANGEMENTS IN A GroEL-ATP COMPLEX |
| 10:30 a.m. - 11:00 a.m. | Coffee Break |
| 11:00 a.m. - 11:40 a.m. | Steven Ludtke (Baylor College of Medicine)
SEMIAUTOMATED SINGLE-PARTICLE ANALYSIS FOR FAST, ACCURATE STRUCTURES |
| 11:40 a.m. - 12:20 p.m. | Peter Frederik (Maastricht)
CONTROLLED AND CONSISTENT PREPARATION OF CRYO-EM SAMPLES |
| 12:20 p.m. - 1:30 p.m. | Lunch |
| 1:30 p.m. - 4:00 p.m. | Free of all Formal Activity |
| 4:30 p.m. - 6:00 p.m. | Poster Sessions |
| 6:00 p.m. - 7:30 p.m. | Dinner |
| 7:30 p.m. - 9:45 p.m. | Theme: High Throughput with 2-Dimensional Arrays |
| (Discussion Leader: Sriram Subramaniam; NIH ) |
| 7:30 p.m. - 7:45 p.m. | INTRODUCTION AND OVERVIEW |
| 7:45 p.m. - 8:25 p.m. | Eva Nogales (UC Berkeley)
THE REFINED STRUCTURE OF TUBULIN |
| 8:25 p.m. - 9:05 p.m. | Werner Kuhlbrandt (Frankfurt)
STRUCTURAL BIOLOGY OF MEMBRANE TRANSPORT |
| 9:05 p.m. - 9:45 p.m. | David Stokes (Skirball Inst., New York)
CONFORMATIONAL CHANGES IN THE Ca-ATPase TRANSPORT CYCLE |
| Tuesday, June 26 |
| 7:30 a.m. - 8:30 a.m. | Breakfast |
| 9:00 a.m. - 12:20 p.m. | Theme: Tomography |
| (Discussion Leader: Richard McIntosh; Boulder) |
| 9:00 a.m. - 9:20 a.m. | INTRODUCTION TO ELECTRON TOMOGRAPHY AND A PERSPECTIVE ON THE RECONSTRUCTION OF LARGE CELLULAR VOLUMES |
| 9:20 a.m. - 9:55 a.m. | Kenneth Taylor (Tallahassee)
INSIGHTS INTO THE MECHANISM OF MUSCLE CONTRACTION OBTAINED USING ELECTRON TOMOGRAPHY |
| 9:55 a.m. - 10:30 a.m. | Clair Baldock (Manchester)
FIBRILLIN MICROFIBRILS IN THE EXTRACELLULAR MATRIX |
| 10:30 a.m.-11:00 a.m. | Coffee Break |
| 11:00 a.m. - 11:35 a.m. | Bruce McEwen (Albany, NY)
LIMITATIONS TO WHAT CAN BE SEEN BY CRYO- AND PLASTIC SECTION ELECTRON TOMOGRAPHY
|
| 11:35 a.m. - 12:20 p.m. | Wolfgang Baumeister (Martinsried)
LOW-DOSE TOMOGRAPHY OF FROZEN-HYDRATED WHOLE CELLS AND ORGANELLES |
| 12:30 p.m. - 1:30 p.m. | Lunch |
| 1:30 p.m. - 4:00 p.m. | Free of all Formal Activity |
| 4:30 p.m. - 6:00 p.m. | Poster Sessions |
| 6:00 p.m. - 7:30 p.m. | Dinner |
| 7:30 p.m. - 9:45 p.m. | Platform Presentations of Selected Posters: Single Particles |
| (Discussion Leader: TBA) |
| Wednesday, June 27 |
| 7:30 a.m. - 8:30 a.m. | Breakfast |
| 9:00 a.m. - 12:20 p.m. | Theme: Automating Microscope Operation for High Throughput Data Acquisition |
| (Discussion Leader: Ronald Milligan; Scripps, San Diego) |
| 9:00 a.m. - 9:10 a.m. | INTRODUCTION AND OVERVIEW |
| 9:10 a.m. - 9:50 a.m. | Bridget Carragher, (Scripps, San Diego)
AUTOMATION FOR CRYO-TEM: FROM SPECIMEN GRID TO 3-D MAP |
| 9:50 a.m. - 10:30 a.m. | Peijun Zhang (NIH)
AUTOEM: AN AUTOMATED DATA COLLECTION SYSTEM FOR "SINGLE MOLECULE" ELECTRON MICROSCOPY |
| 10:30 a.m.-11:00 a.m. | Coffee Break |
| 11:00 a.m. - 11:40 a.m. | Paul Mooney (Gatan)
ADVANCING THE TECHNOLOGY OF DIRECT ELECTRONIC READOUT OF HIGH-RESOLUTION IMAGES |
| 11:40 a.m. - 12:20 p.m. | James Holton (UC Berkeley)
ELVES - AUTOMATED CONTROL OF CRYSTALLOGRAPHIC SOFTWARE: A PROTOTYPE FOR COMPARABLE TASKS IN ELECTRON MICROSCOPY
|
| 12:30 p.m. - 1:30 p.m. | Lunch |
| 1:30 p.m. - 4:00 p.m. | Free of all Formal Activity |
| 4:30 p.m. - 6:00 p.m. | Poster Sessions |
| 6:00 p.m. - 7:30 p.m. | Dinner |
| 7:15 p.m. - 7:30 p.m. | Business Meeting |
| 7:45 p.m. - 9:45 p.m. | Platform Presentations of Selected Posters: Ordered Arrays |
| (Discussion Leader: TBA) |
| Thursday, June 28 |
| 7:30 a.m. - 8:30 a.m. | Breakfast |
| 9:00 a.m. - 12:20 p.m. | Theme: High Throughput with Ordered Assemblies |
| (Discussion Leader: Keiichi Namba; Kyoto) |
| 9:00 a.m. - 9:10 a.m. | INTRODUCTION AND OVERVIEW |
| 9:10 a.m. - 9:50 a.m. | Huilin Li (Lawrence Berkeley National Lab)
TREATING MICROTUBULES AS A STRING OF SINGLE PARTICLES |
| 9:50 a.m. - 10:30 a.m. | Masahide Kikkawa (Tokyo)
ATOMIC MODEL OF MONOMERIC KINESIN MOTOR KIF1A |
| 10:30 a.m.-11:00 a.m. | Coffee Break |
| 11:00 a.m. - 11:40 a.m. | Koji Yonekura (Kyoto)
VISUALIZATION OF SECONDARY-STRUCTURE IN THE EM DENSITY OF BACTERIAL FLAGELLAE |
| 11:40 a.m. - 12:20 p.m. | Marin van Heel (London)
ATOMIC-RESOLUTION STRUCTURE OF A VIRUS PARTICLE |
| 12:30 p.m. - 1:30 p.m. | Lunch |
| 1:30 p.m. - 4:00 p.m. | Free of all Formal Activity |
| 4:30 p.m. - 6:00 p.m. | Poster Sessions |
| 6:00 p.m. - 7:30 p.m. | Dinner |
| 7:30 p.m. - 9:40 p.m. | Theme: Quantifying Hybrid-Interpretation of Density Maps |
| (Discussion Leader: Niels Volkmann; Burnham, San Diego) |
| 7:30 p.m. - 7:40 p.m. | INTRODUCTION AND OVERVIEW |
| 7:40 p.m. - 8:20 p.m. | Chris Gilmore (Glasgow)
DO WE NEED IMAGES? WORKING WITH DIFFRACTION DATA AND MAXIMUM ENTROPY |
| 8:20 p.m. - 9:00 p.m. | Alwyn Jones (Upsala)
ERRORS IN BUILDING MODELS. WHAT IS TO BE LEARNED FROM CRYSTALLOGRAPHY? |
| 9:00 p.m. - 9:40 p.m. | Jorge Navaza (Gif-sur-Yvette)
FITTING CRYSTAL STRUCTURES INTO EM RECONSTRUCTIONS: A SPACE-FREQUENCY APPROACH |
| Friday, June 29 |
| 7:30 a.m. - 8:30 a.m. | Breakfast |
