Technical Advances in 3DEM to Study Biological Structures Across Scales

The 2022 Gordon Research Conference on Three-Dimensional Electron Microscopy will continue its tradition of highlighting the latest technical developments, breakthroughs and future trends in 3DEM for studying biological structures across scales.

Single particle cryo-electron microscopy and cellular cryo-electron tomography have become powerful and widely used tools for studying the structure and function of biological complexes. Technological innovations in hardware, software, and sample preparation methods continue to push limits and open new possibilities, e.g. for visualizing protein complex dynamics, determining the structures of smaller and more flexible proteins, and using tomography to observe 3D structures, conformations and spatial relationships of molecules inside cells. In addition to presenting recent technical advances and innovative ways in which 3DEM is being applied, we will also discuss new and ongoing challenges in the field, such as, automation, data validation, data curation and targeted sample preparation for cells and tissues.

The meeting will provide a unique mixture of scientific oral and poster presentations, and ample opportunities to exchange ideas and discuss the challenges and opportunities in the 3DEM field among senior and junior scientists, mentors and trainees, established cryo-EM experts and new-comers, academics and industry researchers at social events and poster sessions. Following the tradition of 3DEM GRCs, the 2022 meeting encourages participants to present recent and unpublished scientific results, in both oral and poster presentations. Two evening sessions are dedicated to presentations selected from posters at the meeting. As in every year, due to limited attendance (<200 participants) and the over-subscribed nature of previous meetings, early registration is encouraged. In your application, please provide information, such as your research, poster title, and your advisor/PI (for junior members of our community).