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Three Dimensional Electron Microscopy (GRS)

Gordon Research Seminar

Visualizing Biological Complexity Across Scales in 3DEM

October 30 - 31, 2021
Chairs and
Waterville Valley
56 Packard's Road
Waterville Valley, New Hampshire, United States
 Venue and Travel Information

Conference Description

The Gordon Research Seminar on Three Dimensional Electron Microscopy is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The cryo-EM revolution is continuing to provide insight into ever larger and more complex biomolecular systems. This meeting will focus on new techniques and experiments that increase our understanding of the structure and function of biomolecules at multiple scales, putting detailed molecular structures into their cellular context. There will be plenty of opportunity for early-career scientists to present their work and make connections with other junior researchers to shape the future of the field.

Related Meeting

This GRS will be held in conjunction with the "Three Dimensional Electron Microscopy" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Structure among the Chaos: Using Cellular Tomography to Study Mitochondrial Behavior
Discussion Leader:
3:45 pm - 3:55 pm
Introduction by Discussion Leader
3:55 pm - 4:20 pm
"Structure Among the Chaos: Using Cellular Tomography to Study Mitochondrial Behavior"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Putting Structures in Context
Discussion Leader:
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 7:50 pm
"In Situ Architecture and Dynamics of Bacterial Cell Division Dictate Polar Shape"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:05 pm
"Quantitative Structural Analysis of Influenza Virus by Cryo-Electron Tomography and Convolutional Neural Networks"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"In Cellulo Cryo-CLEM Reveals the Antiviral Effect of IFITM3 by Arresting the Hemifusion State During Influenza A Virus Membrane Fusion"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:35 pm
"Exploring In Situ Viral Infection with Multi-Modal Cryogenic Correlative FLM-FIB/SEM for Vitrified Mammalian Cells"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"In Situ Cryo-Electron Tomography of the ER-Mitochondria Encounter Structure in Yeast"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:05 pm
"In Situ Structural Analysis of the Nuclear Pore Complex in Drosophila melanogaster Egg Chambers"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:20 pm
"Membrane Tension Regulates Nuclear Pore Diameter"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Understanding Structural Dynamics
Discussion Leader:
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:20 am
"Structure of the Human Mediator-Bound Transcription Preinitiation Complex"
9:20 am - 9:25 am
Discussion
9:25 am - 9:35 am
"Structure of the Human SAGA Coactivator Complex"
9:35 am - 9:40 am
Discussion
9:40 am - 9:50 am
"Broadly Neutralizing β-Coronavirus Antibodies that Protect Against SARS-CoV-2 Variants of Concern by Blocking the Fusion Machinery"
9:50 am - 9:55 am
Discussion
9:55 am - 10:05 am
"Emerging SARS-CoV-2 Variants: How Natural Mutations Impact the Structure, Conformation and Antigenicity of the Spike Protein"
10:05 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Ab Initio Helical Indexing in Real Space Without the Need for Fourier Layer Lines"
10:20 am - 10:25 am
Discussion
10:25 am - 10:35 am
"The Cellular Environment Shapes the Nuclear Pore Complex Architecture"
10:35 am - 10:40 am
Discussion
10:40 am - 10:50 am
"CSTET: A Window into the Cell"
10:50 am - 10:55 am
Discussion
10:55 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: How to Make the Most Out of Scientific Networking
Discussion Leader:
1:30 pm - 2:15 pm
Panel Discussion
How to Make the Most out of Scientific Networking
2:15 pm - 2:30 pm
Closing Remarks
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes

Contributors

CCP-EM - Collaborative Computational Project for Electron Cryo-Microscopy
Gordon and Betty Moore Foundation
JEOL, Ltd.
TVIPS - Tietz Video and Image Processing Systems GmbH
Structura Biotechnology Inc.
Gatan, Inc.

Conference Links

Conference History Three Dimensional Electron Microscopy
Additional Fee Info

Three Dimensional Electron Microscopy
June 15 - 20, 2025


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