Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Structural Studies of Cryo-EM Telomerases
3:15 pm - 3:20 pm
Introduction by Discussion Leader
3:20 pm - 3:50 pm
"Visualisation of Human Telomerase Holoenzyme by Cryo-EM"
3:50 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Novel Sample and Grid Preparation Methods in Cryo-EM
Novel sample and grid preparation methods for cryo-EM
5:30 pm - 5:40 pm
"Using Streptavidin Affinity Grids to Visualize Difficult Biological Samples"
5:40 pm - 5:45 pm
Discussion
5:45 pm - 5:55 pm
"Use of the chamaleon for Cryo-EM Studies of Ribonucleotide Reductase"
5:55 pm - 6:00 pm
Discussion
6:00 pm - 6:10 pm
"Capturing Inhibited Assemblies of the Membrane Attack Complex"
6:10 pm - 6:15 pm
Discussion
6:15 pm - 6:25 pm
"Don't Purify in Vein! Structural Insights from Red Blood Cell Lysate"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"FIB-Milling for Single Particle Tomography"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
"Parallel Cryo-ET on in situ Lamellae"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
"A Clonable Selenium Nanoparticle (cSeNP)"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:30 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Emerging Tools for Studying Conformational Variability by Cryo-EM
Emerging tools for studying conformational landscapes by cryo-EM and their biological applications
9:00 am - 9:10 am
"Dissecting the Dynamic Conformational Landscape of Functional RNAs by Cryo-EM"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"Conformation and Dynamics of the AAA ATPase p97"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Using Volta Phase Plate to Study Heterogenous Human Translation Initiation Complexes"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Particles of Confederation - Reliably Expanding Particle Sets by Machine-Learning Consensus"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Zernikes3D: A Continuous Heterogeneity Tool for Cryo-EM Maps and Atomic Models"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"TomoFlow: A New Method for Analyzing Heterogeneous Subtomogram Datasets"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
"In-situ Analysis of SARS-CoV-2 Spike Proteins on Intact Virions"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
"Retrieving Biological Function from Time-Resolved Single-Particle Cryo-EM"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Scientific Publishing
1:30 pm - 1:35 pm
Introduction by Discussion Leader
1:35 pm - 1:55 pm
"Behind the Scenes: An Editor's Perspective on Publishing"
1:55 pm - 2:00 pm
Discussion
2:00 pm - 2:30 pm
Panel Discussion
Scientific Publishing
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes