Frontiers of Science

Find a Conference

Alert - GRC systems are offline for approximately one week. For more information, please click here.

Three Dimensional Electron Microscopy (GRS)

Gordon Research Seminar

Advances in 3DEM to Address Complex Biological Questions

June 10 - 11, 2023

Chairs

and

Grand Summit Hotel at Sunday River

97 Summit Road

Newry, Maine, United States

Venue and Travel Information

Conference Description

The Three Dimensional Electron Microscopy GRS provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

Since leaving its mark as a technique ensuing ‘resolution revolution’ in structural biology, cryo-EM is evolving every day. The boundaries are being pushed to obtain high-resolution structures of near-native macromolecular samples. Cryo-ET is swiftly developing alongside and providing answers to the biological questions by visualizing protein complexes, organelles, unique interactions in unprecedented details in the cellular context. This meeting will provide trainees a platform for sharing their research in the field, discussion on current challenges and possible solutions at various stages of the process, technical advances, peer-mentoring, and networking.

Related Meeting

This GRS will be held in conjunction with the "Three Dimensional Electron Microscopy" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm	Keynote Session: The Power of 3DEM in Cellular and Molecular Biology Discussion Leader:
3:45 pm - 3:50 pm	Introduction by Discussion Leader
3:50 pm - 4:05 pm	"Developing Technologies for Correlative Cryo-Imaging Pipelines"
4:05 pm - 4:10 pm	Discussion
4:10 pm - 4:25 pm	"Structural Mechanism of Heat-Induced Opening of a Temperature-Sensitive TRP Channel"
4:25 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Revolutionizing Biology Using 3DEM Discussion Leader:
7:30 pm - 7:40 pm	Introduction by Discussion Leader
7:40 pm - 7:50 pm	"Understanding Cidec-Mediated Neutral Lipid Transfer Between Lipid Droplets In situ and In vitro"
7:50 pm - 7:55 pm	Discussion
7:55 pm - 8:05 pm	"Elucidating Lipid Transport Systems in Bdellovibrio Bacteriovorus"
8:05 pm - 8:10 pm	Discussion
8:10 pm - 8:20 pm	"Structures of a-Synuclein Filaments from Human Brains with Lewy Pathology"
8:20 pm - 8:25 pm	Discussion
8:25 pm - 8:35 pm	"In situ Structural Organization of an Autophagy Cargo Receptor Studied with a Correlative Light and Electron Microscopy Pipeline"
8:35 pm - 8:40 pm	Discussion
8:40 pm - 8:50 pm	"Investigating the Architecture of Tau Aggregates In situ with Cryo-CLEM and Cryo-ET"
8:50 pm - 8:55 pm	Discussion
8:55 pm - 9:05 pm	"Structural Studies of A Dynamic Human Centrosomal Scaffold by Electron Microscopy"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:20 pm	"Integrating Structural and Dynamic Data within 3D Molecular Animations"
9:20 pm - 9:25 pm	Discussion
9:25 pm - 9:30 pm	General Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Novel Technical and Software Developments in 3DEM Discussion Leader:
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:20 am	"Lipid Nanotubules Enable Optimized Specimen Preparation and Processing For Cryo-EM"
9:20 am - 9:25 am	Discussion
9:25 am - 9:35 am	"Time-Resolved Cryo-EM of G Protein Activation by a GPCR"
9:35 am - 9:40 am	Discussion
9:40 am - 9:50 am	"FilamentID: An Integrated CryoEM Approach to Identify Metabolic Filament Assemblies"
9:50 am - 9:55 am	Discussion
9:55 am - 10:05 am	"Genetically Encoded Multimeric (GEM) Tags for Intracellular Protein Localization in Cellular Cryo-ET"
10:05 am - 10:10 am	Discussion
10:10 am - 10:20 am	"Cryo-Electron Microscopy with a Laser Phase Plate"
10:20 am - 10:25 am	Discussion
10:25 am - 10:35 am	"OccuPy: Heterogeneity- and Occupancy-Aware Cryo-EM Analysis Based on Spatial Filtering"
10:35 am - 10:40 am	Discussion
10:40 am - 10:50 am	"Hybrid Methods Combining MD Simulations & Cryo-EM"
10:50 am - 10:55 am	Discussion
10:55 am - 11:00 am	General Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Career Paths in 3DEM Discussion Leaders: and
1:30 pm - 1:40 pm	Introduction by Discussion Leader
1:40 pm - 2:30 pm	Panel Discussion Career Panel
2:30 pm - 3:00 pm	Evaluation Period Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm	Seminar Concludes

Contributors

Conference Links

Conference History Three Dimensional Electron Microscopy

Similar Conferences

Registration Fees Additional Fee Info

Similar Gordon Research Conferences and Seminars

Three Dimensional Electron Microscopy

June 15 - 20, 2025

Contact Us

MyGRC Account
Check your application status, complete your registration, update your poster, change your rooming preference, make a bus reservation, print an invitation letter, print a receipt (which includes verification that you are presenting a poster) or print an invoice by logging into your account.

GRC Venues
Everything you need to know, to plan your trip.

FAQs
Instant answers to common questions.

Tell us how we can help

Call us and leave a detailed message at: 401-783-4011

*This voicemail is only checked once daily. Due to high volume of requests during the conference season, responses may be delayed.

You have no notifications