The Gordon Conference on Thrombolysis will focus on all aspects of the cellular and molecular biology of plasminogen activation, the process by which the multi-functional serine protease, plasmin, is formed. The program will cover the structure and function of plasminogen activators; regulation of plasmin generation by cofactors, receptors, and inhibitors; and control of expression of fibrinolytic genes. Additional sessions will address newly described roles of fibrinolytic proteins in cell signaling events, blood vessel formation, and atherogenesis. Finally, the conference will explore the contributions of genetic animal models of human vascular disease, and the potential utility of emerging therapeutic modalities.
