Exploring Multimodal Perspectives on Tissue Microstructures

The Tissue Microstructure Imaging GRC focuses on advancing the frontiers of tissue, cellular and sub-cellular imaging. The fundamental objective of the meeting is to offer a unifying look at the tissue microstructure based on all available complementary vantage points, using magnetic resonance imaging, ultrasound, optical and electron microscopy, x-ray, photoacoustic and other modalities. The conference stimulates cross-pollination and validation of different imaging techniques, models and analysis tools. The same tissue, viewed through the prism of different imaging modalities, looks distinctly different, as each of them has its own unique scope of relevant tissue parameters and scales. The practical objectives are to compare different imaging methods from the point of providing accurate, robust and biologically relevant assessment of tissue microstructure and function, pathological and developmental changes, and response to treatment

The 2023 GRC Tissue Microstructure Imaging was the second edition and it already established a vibrant community of scientists open to communicating their methods to other imaging modalities. Our goal for 2025 is to build on this enthusiasm and uncover, explore and exploit complementarities and synergies, to help us validate and cross-validate our methods.To build interdisciplinary connections, the invited speakers will be specifically asked to address the physiological or pathological characteristics they target, the specificities of their modalities of choice and their unresolved issues requiring the contributions of other modalities. This meeting will help us borrow and adapt methodologies of image reconstruction, modeling and validation of tissue architecture and function, to make tissue microstructure imaging greater than the sum of its parts.