| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-In |
| 6:00 pm | Dinner |
| 7:30 pm - 7:40 pm | Welcome, Bill Parks and & GRC Staff |
| 7:40 pm - 9:30 pm | EPITHELIAL REPAIR |
| Discussion Leader: Sabine Werner (Swiss Institute of Technology). |
| 7:40 pm - 8:15 pm | Barry Stripp (University of Pittsburgh)
Stem cells and cell lineage relationships in the adult conducting airway |
| 8:15 pm - 8:50 pm | Gregory Longmore (Washington University)
LIM proteins and cell migration |
| 8:50 pm - 9:25 pm | Liliane Michalik (Université de Lausanne)
Critical roles of the nuclear hormone receptor PPARß in wound healing |
| 9:30 pm | Welcoming Reception |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | MECHANICS OF CELL MIGRATION |
| Discussion Leader: Pierre Coulombe (Johns Hopkins University) |
| 9:00 am - 9:35 am | Charles Little (University of Kansas)
Forces that shape tissues during embryogenesis: dynamic computational analysis |
| 9:35 am - 10:10 am | Melody Swartz (Northwestern University)
Restoration of fluid balance and lymphangiogenesis in regenerated skin |
| 10:10 am - 10:30 am | John K. McGuire (Washington University)
Matrilysin (MMP-7) mediates E-cadherin shedding in injured lung epithelium |
| 10:30 am | Group Photo and Coffee Break |
| 11:00 am - 11:35 am | Rama Khokha (Ontario Cancer Institute)
Metalloproteinases and cell signaling during liver regeneration |
| 11:35 am - 11:55 am | Nancy Boudreau (University of California San Francisco)
Homeobox genes accelerate diabetic wound repair |
| 11:55 am - 12:30 pm | Pierre Coulombe (Johns Hopkins University)
Mechanical insight into the re-epithelialization of skin wounds |
| 12:30 pm | Lunch |
| 1:30 pm - 4:30 pm | Free Time |
| 4:30 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | ROLE OF INFLAMMATION ON REPAIR PROCESSES |
| Discussion Leader: Jay Heinecke (University of Washington) |
| Jay Heinecke (University of Washington) |
| 5:30 pm - 6:05 pm | Luisa DiPietro (Loyola University Chicago)
Chemokines, inflammation, and tissue repair |
| 6:05 pm - 6:40 pm | Pyong Woo Park (Baylor College of Medicine)
Functions of proteoglycans in inflammation |
| 6:40 pm - 7:00 pm | Linda Sandell (Washington University)
IL-1 and TNF stimulate a repair response in human osteoarthritic chondrocytes through induction of BMP-2 |
| 7:00 pm - 7:35 pm | Jay Heinecke (University of Washington)
Inactivation of metalloproteinases by activated phagocytes: An inflammatory pathway for making kinky proteins |
| 8:00 pm | Dinner |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | TISSUE REGENERATION |
| Discussion Leader: Paul Martin (University College London) |
| 9:00 am - 9:35 am | Jonathan M.W. Slack (University of Bath)
Regeneration of spinal cord and muscle in a vertebrate |
| 9:35 am - 10:10 am | Malcolm Maden (Kings College London)
Retinoids and lung development and regeneration |
| 10:10 am - 10:30 pm | Panagiotis A. Tsonis (University of Dayton)
Molecular mechanisms in the induction of lens regeneration |
| 10:30 am | Coffee Break |
| 11:00 am - 11:35 am | Jo Price (Royal Veterinary College)
Deer antlers as a model of mammalian regeneration |
| 11:35 am - 11:55 am | Marijana Miljkovic-Licina (University of Geneva)
Reactivation of developmental programs in hydra : Initiation of budding and regeneration rely on distinct molecular mechanisms |
| 11:55 am - 12:30 pm | Paul Martin (University College London)
Wound repair in embryos |
| 12:30 pm | Lunch |
| 1:30 pm - 4:30 pm | Free Time |
| 4:30 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | CYTOKINES: CELL SIGNALING IN REPAIR |
| Discussion Leader: Anita Roberts (National Institutes of Health) |
| 5:30 pm - 6:05 pm | Sabine Werner (Swiss Institute of Technology)
Cytoprotective signaling pathways in wounded skin |
| 6:05 pm - 6:40 pm | Shizuya Saika (Wakayama Medical University)
Regulation of epithelial-mesenchymal transition by extracellular matrix and growth factors in tissue repair |
| 6:40 pm - 6:55 pm | Richard Grose (Cancer Research UK)
FGF signaling in skin development and repair |
| 6:55 pm - 7:10 pm | David Warburton (University Southern California)
Sprouty, Shp2 tyrosine phosphatase and FRS2 supramolecular complex assembly finely modulates downstream FGF signaling in lung morphogenesis, repair and regeneration. |
| 7:10 pm - 7:35 pm | Peter Angel (German Cancer Research Center)
Function of AP-1 subunits in skin physiology and pathology |
| 8:00 pm | Dinner |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | SCARRING & FIBROSIS |
| Discussion Leader: Mark W.J. Ferguson (University of Manchester) |
| 9:00 am - 9:35 am | Paul Noble (Yale University)
Hyaluronan and CD44 in tissue injury and repair |
| 9:35 am - 10:10 am | Steven Weintraub (Washington University)
Regulation of the proliferative response to increased tissue tension |
| 10:10 am - 10:30 pm | Martin Kolb (Universtät Wüzburg)
TGF ? over-expression causes a resolving fibroproliferative response in rat lung |
| 10:30 am | Coffee Break |
| 11:00 am - 11:35 am | Michael Longaker (Stanford University)
Keratinocyte-fibroblast interactions in keloids |
| 11:35 am - 11:55 am | James Hagood (University of Alabama-Birmingham)
Thy-1 modulates lung fibroblast adhesive and migratory signaling |
| 11:55 am - 12:30 pm | Mark W. J. Ferguson (University of Manchester)
TGF isoforms and scarring: from lab to clinic |
| 12:30 pm | Lunch |
| 1:30 pm - 4:30 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | CONNECTIVE TISSUE REPAIR |
| Discussion Leader: Jack Gauldie (McMaster University) |
| 5:30 pm - 6:05 pm | Alain Mauviel (INSERM Hopital Saint-Louis)
Interfering with the TGFß/Smad pathway: Implications for ECM remodeling |
| 6:05 pm - 6:40 pm | Peter Friedl (Universtät Wüzburg)
Plasticity in tumor cell migration in extracellular matrix: cooperation of integrins and matrix proteases |
| 6:40 pm - 6:55 pm | Patricia Rousselle (BioSciences Lyon-Gerland)
Normal human keratinocytes bind to the 3LG4/5 domain of unprocessed laminin-5 through the receptor syndecan-1 |
| 6:55 pm - 7:10 pm | Antonio Musarò (University of Rome)
Localized expression of IGF-1 enhances the recruitment of circulating stem cells and improves muscle regeneration |
| 7:10 pm - 7:45 pm | Jack Gauldie (McMaster University)
Regulation of chronic fibrogenesis: beyond TGFß |
| 8:00 pm | Dinner |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | INTERVENTION: MAKING THINGS BETTER |
| Discussion Leader: Judith Abraham (Chiron Corporation) |
| 9:00 am - 9:35 am | Anis Sen Majumdar (Geron Corporation)
Telomerase, human embryonic stem cells, and regenerative medicine |
| 9:35 am - 10:10 am | Jeff Rubin (NIH)
KGF ameliorates chemoradiotherapy-associated oral mucositis: positive results in advanced clinical trials |
| 10:10 am - 10:30 pm | Jeffrey Davidson (Vanderbilt University)
Bone marrow derived cells express collagen during wound repair |
| 10:30 am | Coffee Break |
| 11:00 am - 11:35 am | Hynda Kleinman (National Institutes of Health)
Thymosin beta 4 promotes wound repair and hair follicle growth |
| 11:35 am - 11:55 am | Kazuo Kishi (Keio University)
The relationship between shh expression and fetal epidermal regeneration |
| 11:55 am - 12:30 pm | Andreas Goppelt (SWITCH BIOTEC)
Identification of novel injury-regulated genes and their application to cutaneous wound repair |
| 12:30 pm | Lunch |
| 1:30 pm - 5:30 pm | Free Time |
| 5:30 pm - 6:00 pm | Poster Session |
| 6:30 pm - 7:00 pm | BUSINESS MEETING:
Paul Martin and Judith Abraham |
| 6:30 pm - 7:30 pm | FEATURED SPEAKER |
| 7:00 pm - 8:00 pm | Jeff Hubbell (Swiss Institute of Technology)
Bioactive cell invasion matrices for morphogen presentation: examples in skin and bone repair |
| 8:00 pm | Dinner and Farewell Party |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
