SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Danger Signaling - Sensing the Presence of Damage |
| Discussion Leader: Michael J. Galko (University of Texas MD Anderson Cancer Center) |
7:40 pm - 7:45 pm | Welcome / Michael J. Galko (University of Texas MD Anderson Cancer Center) |
7:45 pm - 8:10 pm | Philip Niethammer (Sloan-Kettering)
"Signals that direct inflammation in wounded zebrafish" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Chuan-Yuan Li (University of Colorado School of Medicine)
"Promotion of wound healing/regeneration by apoptotic cells" |
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Carl Hauser (Beth-Israel Deaconess)
"Damage-associated molecular patterns and inflammation" |
9:20 pm - 9:30 pm | Discussion |
9:30 pm | Optional evening social and poster viewing |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Healing the Outside- Barrier Repair and Regeneration |
| Discussion Leader: Tanya Shaw (St. George's) |
9:00 am - 9:05 am | Session Introduction / Tanya Shaw (St. George's) |
9:05 am - 9:30 am | Andrew Chisholm (University of California, San Diego)
"Epidermal wound healing in C. elegans" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:05 am | Yutaka Matsubayashi (Bristol University) "Waves of healing: Analyses of collective cell mobilization during re-epithelialisation of wounds" |
10:05 am - 10:15 am | Discussion |
10:15 am | Coffee Break |
10:40 am - 11:05 am | Stephen Jane (Rotary Bone Marrow Research Laboratory)
"Grainyhead factors in mouse skin wound healing" |
11:05 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Fiona Watt (Cancer Research UK Cambridge)
"Wound healing and epithelial cancer in mice" |
11:45 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Andrea Page-McCaw (Vanderbilt University) "Drosophila matrix metalloproteases function together to heal wounds" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Building Better Organs: Tissue Engineering |
| Discussion Leader: Jeff Davidson (Vanderbilt University) |
7:30 pm - 7:35 pm | Session Introduction / Jeff Davidson (Vanderbilt University) |
7:35 pm - 8:00 pm | Jennifer West (Rice University)
"Engineering vascular scaffolds for repair" |
8:00 pm - 8:12 pm | Discussion |
8:12 pm - 8:37 pm | Ravi Bellamkonda (Georgia Technical University)
"Engineered scaffolds for nervous system repair" |
8:37 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Dennis Discher (University of Pennsylvania)
"Matrix elasticity as a trafficking and lineage cue for stem cells" |
9:15 pm - 9:30 pm | Discussion |
9:30 pm | Optional evening social and poster viewing |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Healing the Inside: Organ Repair and Regeneration |
| Discussion Leader: Enrique Amaya (University of Manchester) |
9:00 am - 9:05 am | Session Introduction / Enrique Amaya (University of Manchester) |
9:05 am - 9:30 am | Grace Pavlath (Emory University)
"Muscle regeneration in mice" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:05 am | Sirio Dupont (University of Padua) "Identification of a novel nuclear mediator for cell mechanical responses to ECM stiffness/cell geometry" |
10:05 am - 10:15 am | Discussion |
10:15 am | Coffee Break |
10:40 am - 11:05 am | Alvaro Sagasti (University of California at Los Angeles)
"Interplay between epidermis and sensory neurons during zebrafish regeneration" |
11:05 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Shahin Rafii (Cornell Weill Medical College)
"Mouse liver regeneration" |
11:45 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Shawn Burgess (NHGRI) "The Stat3/Socs3 pathway is a key regulator of hair cell regeneration in Zebrafish" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session II |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Cancer as a Disease of Misregulated Wound Healing |
| Discussion Leader: Yutaka Matsubayashi (University of Bristol) |
7:30 pm - 7:35 pm | Session Introduction / Yutaka Matsubayashi (University of Bristol) |
7:35 pm - 8:00 pm | Sabine Werner (ETH Zurich)
"Cancer/wound healing connections in mice" |
8:00 pm - 8:12 pm | Discussion |
8:12 pm - 8:37 pm | Alan Wells (University of Pittsburgh)
"Tumors -- the wound that won't STOP healing" |
8:37 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Paul Martin (University of Bristol)
"Innate immune cell sensing of transformed cells in zebrafish" |
9:15 pm - 9:30 pm | Discussion |
9:30 pm | Optional evening social and poster viewing |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Regenerating Pattern Throughout the Animal Kingdom |
| Discussion Leader: Dunja Knapp (Max Planck Institute of Molecular Cell Biology and Genetics) |
9:00 am - 9:05 am | Session Introduction / Dunja Knapp (MPI-MCBG) |
9:05 am - 9:30 am | Brigitte Galliot (University of Geneva)
"Cell death as a driving force for regeneration" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:05 am | T. Harshani Peiris (University of California at Merced)
"TOR signaling distinguishes regenerative from homeostatic stem cells in planaria" |
10:05 am - 10:15 am | Discussion |
10:15 am | Coffee Break |
10:40 am - 11:05 am | Rachel Smith-Bolton (University of Illinois at Urbana-Champaign)
"A genetically tractable regeneration response in Drosophila larvae" |
11:05 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Karen Echeverri (Center for Regenerative Therapies Dresden - CRTD)
"MicroRNAs and Axolotl Regeneration" |
11:45 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Yuval Rinkevich (Stanford University School of Medicine) "Germ layer and lineage restriction of stem and progenitor cells during mouse digit tip regeneration" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session III |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Keeping the Bad Guys Out: Inflammation |
| Discussion Leader: Joe Leibovich (University of Medicine and Dentistry of New Jersey) |
7:30 pm - 7:35 pm | Session Introduction / Joe Leibovich (UMDNJ) |
7:35 pm - 8:00 pm | Will Wood (University of Bath)
"Macrophage migration and inflammation in Drosophila embryos" |
8:00 pm - 8:12 pm | Discussion |
8:12 pm - 8:37 pm | Sabine Eming (University of Cologne)
"Macrophages in skin repair" |
8:37 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Takeo Kubo (University of Tokyo)
"Immunosuppression reactivates Xenopus tail regeneration during the refractory period" |
9:15 pm - 9:30 pm | Discussion |
9:30 pm | Optional evening social and poster viewing |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
9:00 am - 12:30 pm | Helping Repair the Damage: Stem Cells and Regenerative Medicine |
| Discussion Leader: Luisa DiPietro (University of Illinois at Chicago) |
9:00 am - 9:05 am | Session Introduction / Luisa DiPietro (UIC) |
9:05 am - 9:30 am | Geoff Gurtner (Stanford University)
"Stem cells in tissue repair" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:05 am | Isaac Brownell (NCI) "Sonic Hedgehog and the perineural niche regulate hair follicle stem cells" |
10:05 am - 10:15 am | Discussion |
10:15 am | Coffee Break |
10:40 am - 11:05 am | Leena Bruckner-Tuderman (University of Freibourg)
"Stem cell therapeutics for skin diseases" |
11:05 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Michele De Luca (University of Modena)
"Limbal Stem Cells in Corneal Regeneration" |
11:45 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | David Becker (University College London) "Targeting abnormal Connexin-43 expression in venous leg ulcer clinical trials" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session IV |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Matrix and Fibrosis |
| Discussion Leader: Sabine Eming (University of Cologne) |
7:30 pm - 7:35 pm | Session Introduction / Sabine Eming (University of Cologne) |
7:35 pm - 8:00 pm | Daniel Tschumperlin (Harvard School of Public Health)
"Matrix stiffness as a regulator of fibrosis" |
8:00 pm - 8:12 pm | Discussion |
8:12 pm - 8:37 pm | Karl Kadler (University of Manchester)
"Understanding how tissue precursor cells synthesize and tension a collagen fibril-rich matrix" |
8:37 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Lester Lau (University of Illinois at Chicago)
"Fibrosis and wound healing" |
9:15 pm - 9:30 pm | Discussion |
9:30 pm | Optional evening social and poster viewing |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |