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Tissue Repair and Regeneration (GRS)

Gordon Research Seminar

Regenerative Engineering: Developing Strategies to Restore Functional Tissues

May 27 - 28, 2023
Chairs and
Colby-Sawyer College
541 Main Street
New London, New Hampshire, United States
 Venue and Travel Information

Conference Description

The Tissue Repair and Regeneration GRS provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

This seminar will highlight the research advances in the growing field of regenerative engineering. This multidisciplinary field combines cell and developmental biology, biomaterials, and tissue engineering methods to understand the processes that underpin the repair and regeneration of tissues in response to injury and disease. In addition to scientific discussion, this meeting will provide trainees and early career investigators with an opportunity to expand their professional network in a highly interdisciplinary environment, receive tailored mentoring from established faculty, and learn strategies to accelerate their scientific career.

Related Meeting

This GRS will be held in conjunction with the "Tissue Repair and Regeneration" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Mechanoregulation of Regeneration
Discussion Leader:
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:20 pm
"Mechanoregulation of Cellular Hypoxia During Bone Repair"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Models and Mechanisms of Repair and Regeneration
Discussion Leader:
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 7:55 pm
"Senescent-Associated Extracellular Matrix Production and Delayed Wound Healing by Senescent Dermal Fibroblasts in a Biomimetic Injury Model"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:15 pm
"Myofibroblast Activation is Induced Through Intracellular Stress in a Calcium-Dependent Process Upon Acute Contact With Profibrotic Macrophages"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
"Modulation of Human Adipose Stem Cell Collagen Synthesis by Mechanosensing of Substrate Architecture Through the Piezo1 Ion Channel"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
"Differential Role of YAP During Wound Response and Tissue Expansion in Regeneration and Fibrosis"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
"Dissecting Vascular Reperfusion and Remodeling After Injury in Zebrafish"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Engineering Strategies for Regenerative Medicine
Discussion Leader:
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
"Digital Model of Tissue Repair Identifies an Early and Transient Decrease in Fiber Linking as Sufficient to Unlock Regeneration in Adult Mammals"
9:25 am - 9:30 am
Discussion
9:30 am - 9:45 am
"Targeting the Extracellular Matrix to Repair Hyperglycemia-Induced Glomerular Injury"
9:45 am - 9:50 am
Discussion
9:50 am - 10:05 am
"Circuit-to-Target Approach Defines an Autocrine Myofibroblast Loop That Drives Cardiac Fibrosis"
10:05 am - 10:10 am
Discussion
10:10 am - 10:25 am
"Engineered Self-Regulating Macrophages for Targeted Anti-Inflammatory Drug Delivery"
10:25 am - 10:30 am
Discussion
10:30 am - 10:45 am
"Mechanical Control of Exosome Formation by Mesenchymal Stromal Cells"
10:45 am - 10:50 am
Discussion
10:50 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Building a Diverse and Inclusive Research Environment
Discussion Leader:
1:30 pm - 1:35 pm
Introduction by Discussion Leader
1:35 pm - 2:30 pm
Panel Discussion
Strategies For Building a Diverse and Inclusive Research Environment
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes

Contributors

Washington University School of Medicine - Center of Regenerative Medicine
Washington University in St. Louis - Musculoskeletal Research Center
University of Washington - Institute for Stem Cell & Regenerative Medicine (ISCRM)
Center for Engineering MechanoBiology (CEMB)
University of California, San Francisco - UCSF Musculoskeletal Center

Conference Links

Conference History Tissue Repair and Regeneration
Additional Fee Info

Tissue Repair and Regeneration
June 1 - 6, 2025


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